論文

査読有り
2012年4月

Minimally Invasive Procedure for Accurate Diagnosis of Mucosa-associated Lymphoid Tissue Lymphoma of the Head and Neck

JAPANESE JOURNAL OF CLINICAL ONCOLOGY
  • Yorihisa Orita
  • ,
  • Yasuharu Sato
  • ,
  • Eisei Kondo
  • ,
  • Hisashi Ishihara
  • ,
  • Haruka Hirai
  • ,
  • Hiroyuki Hanakawa
  • ,
  • Tomoo Onoda
  • ,
  • Takuro Igawa
  • ,
  • Ryusuke Saito
  • ,
  • Kazunori Nishizaki
  • ,
  • Tadashi Yoshino

42
4
開始ページ
325
終了ページ
330
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1093/jjco/hys011
出版者・発行元
OXFORD UNIV PRESS

Sonography-guided cutting needle biopsy for the diagnosis of malignant lymphoma has recently come into wide use. However, surgery is sometimes unavoidable for the diagnosis of malignant lymphoma, particularly for low-grade malignant lymphoma such as extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, because cutting needle biopsy offers limited diagnostic accuracy for low-grade malignant lymphoma. Of course, unnecessary invasive procedures like open biopsy should be avoided wherever possible, given the cosmetic problems and burden on the patient. We tried to diagnose malignant lymphoma using the combination of cutting needle biopsy, flow cytometry and polymerase chain reaction to identify monoclonal rearrangement of immunoglobulin heavy chain genes. We have used this method in two cases in whom malignant lymphoma was suspected in the head and neck region, allowing diagnosis of mucosa-associated lymphoid tissue lymphoma in both cases. One case involved a 23-year-old woman with mucosa-associated lymphoid tissue lymphoma in the parotid glands, and the other involved a 77-year-old man with mucosa-associated lymphoid tissue lymphoma in the thyroid. The combination of cutting needle biopsy, flow cytometry and immunoglobulin heavy chain gene rearrangement testing might offer a useful alternative to open biopsy for the diagnosis of mucosa-associated lymphoid tissue lymphoma. We recommend this procedure, particularly for young women or patients with poor performance status in whom malignant lymphoma is suspected.

Web of Science ® 被引用回数 : 7

リンク情報
DOI
https://doi.org/10.1093/jjco/hys011
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000302308000013&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-84859224172&partnerID=MN8TOARS
URL
http://orcid.org/0000-0003-0995-9405

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