論文

査読有り
2006年6月

Calcineurin inhibitor-induced irreversible neuropathic pain after allogeneic hematopoietic stem cell transplantation

INTERNATIONAL JOURNAL OF HEMATOLOGY
  • N Fujii
  • ,
  • K Ikeda
  • ,
  • M Koyama
  • ,
  • K Aoyama
  • ,
  • T Masunari
  • ,
  • E Kondo
  • ,
  • T Matsuzaki
  • ,
  • S Mizobuchi
  • ,
  • A Hiraki
  • ,
  • T Teshima
  • ,
  • K Shinagawa
  • ,
  • F Ishimaru
  • ,
  • M Tanimoto

83
5
開始ページ
459
終了ページ
461
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1532/IJH97.05154
出版者・発行元
CARDEN JENNINGS PUBL CO LTD

The calcineurin inhibitors (Cls) cyclosporine A and tacrolimus are essential for graft-versus-host disease prophylaxis but are associated with adverse effects, including neurotoxicity We report a case of irreversible Cl-induced neuropathic pain following allogeneic hematopoietic stem cell transplantation. The patient developed dysesthesia, electric shock-like pain. and severe itching followed by intractable analgesic-resistant pain in the lower extremities. There were no abnormal radiographic findings, and there was no improvement with a reduction of Cl dosage or with administration of a calcium channel blocker. These clinical findings are similar to but inconsistent with Cl-induced musculoskeletal pain syndromes previously reported in organ transplantation.

Web of Science ® 被引用回数 : 27

リンク情報
DOI
https://doi.org/10.1532/IJH97.05154
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000238699600016&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-33751061489&partnerID=MN8TOARS
URL
http://orcid.org/0000-0003-0995-9405

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