論文

査読有り
2001年1月

Peripheral T/natural killer-cell lymphoma involving the female genital tract: A clinicopathologic study of 5 cases

INTERNATIONAL JOURNAL OF HEMATOLOGY
  • S Nakamura
  • ,
  • M Kato
  • ,
  • K Ichimura
  • ,
  • Y Yatabe
  • ,
  • Y Kagami
  • ,
  • R Suzuki
  • ,
  • H Taji
  • ,
  • E Kondo
  • ,
  • S Asakura
  • ,
  • M Kojima
  • ,
  • S Murakami
  • ,
  • K Yamao
  • ,
  • T Tsuzuki
  • ,
  • K Adachi
  • ,
  • A Miwa
  • ,
  • T Yoshida

73
1
開始ページ
108
終了ページ
114
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/BF02981911
出版者・発行元
CARDEN JENNINGS PUBL CO LTD

Malignant lymphoma of the female genital tract (FGT) is rare. In this study, 5 peripheral T/natural killer (NK)-cell lymphomas (PTCLs) involving the FGT are reported. They include 2 from the uterus and 1 each from ovary, uterus and ovary, and vagina, and were detected between 1996 and 2000. One of the 2 ovarian tumors was bilateral. In all cases, the FGT was the initial site of clinical presentation of disease. Age at presentation ranged from 21 to 52 years (median, 36 years). One case was stage I disease, 2 were stage II, and 2 were stage IV. All 5 tumors were positive for CD3 epsilon, and 3 harbored the Epstein-Barr virus, although the detailed immunophenotypic profiles varied. Three were diagnosed as nasal type T/NK-cell lymphoma, 1 as anaplastic large-cell lymphoma (anaplastic lymphoma kinase [ALK]-positive), and 1 as unspecified PTCL of cytotoxic phenotype, according to the forthcoming World Health Organization classification. Four of 5 patients received laparotomy and chemotherapy. Four patients tin stages II and IV) died of disease within 16 months of the initial diagnosis, whereas only 1 patient tin stage I) is alive without disease at 39 months of follow-up. Our experience in this series provided clinically relevant information on diagnosis, treatment, and outcome for extremely rare tumors of the FGT. (C) 2001 The Japanese Society of Hematology.

Web of Science ® 被引用回数 : 24

リンク情報
DOI
https://doi.org/10.1007/BF02981911
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000169400700016&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035235269&partnerID=MN8TOARS
URL
http://orcid.org/0000-0003-0995-9405

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