論文

査読有り
2018年5月1日

Risk and incidence of perioperative deep vein thrombosis in patients undergoing gastric cancer surgery

Surgery Today
  • Tomohiro Osaki
  • ,
  • Hiroaki Saito
  • ,
  • Yoji Fukumoto
  • ,
  • Yusuke Kono
  • ,
  • Yuki Murakami
  • ,
  • Yuji Shishido
  • ,
  • Hirohiko Kuroda
  • ,
  • Tomoyuki Matsunaga
  • ,
  • Kengo Sato
  • ,
  • Yasuaki Hirooka
  • ,
  • Yoshiyuki Fujiwara

48
5
開始ページ
525
終了ページ
533
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00595-017-1617-4
出版者・発行元
Springer Tokyo

Background and purpose: Venous thromboembolism (VTE) is a potentially fatal perioperative complication. Understanding the risk factors for deep vein thrombosis (DVT) and initiating appropriate prophylaxis is pivotal for reducing the risk of VTE. The purpose of this study was to clarify the perioperative risk factors for DVT in patients undergoing surgery for gastric cancer. Methods: We reviewed the findings of lower limb ultrasonography performed in 160 patients who underwent gastrectomy for gastric cancer. Results: The preoperative and postoperative incidence of DVT was 4.4% (7/160) and 7.2% (11/153), respectively. All postoperative DVTs were of the distal type, whereas preoperative DVTs were of the proximal (n = 3) and distal type (n = 4). None of the patients suffered symptomatic VTE. Multivariate analysis indicated that depth of invasion and D-dimer concentration were independent risk factors for preoperative DVT and that gender and performance status were risk factors for postoperative DVT. Receiver operating characteristic analysis revealed that the optimal cut-off D-dimer concentration was 1.4 μg/mL. Conclusions: The incidence of perioperative DVT was low for patients undergoing gastric cancer surgery. Therefore, the risk-stratified application of perioperative pharmacologic thromboprophylaxis is thought to be more appropriate than routine pharmacologic thromboprophylaxis for Japanese patients undergoing surgery for gastric cancer.

リンク情報
DOI
https://doi.org/10.1007/s00595-017-1617-4
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29234961
ID情報
  • DOI : 10.1007/s00595-017-1617-4
  • ISSN : 1436-2813
  • ISSN : 0941-1291
  • PubMed ID : 29234961
  • SCOPUS ID : 85037719763

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