論文

査読有り
2018年4月1日

Combined analysis of the preoperative and postoperative prognostic nutritional index offers a precise predictor of the prognosis of patients with gastric cancer

Surgery Today
  • Yuki Murakami
  • ,
  • Hiroaki Saito
  • ,
  • Yusuke Kono
  • ,
  • Yuji Shishido
  • ,
  • Hirohiko Kuroda
  • ,
  • Tomoyuki Matsunaga
  • ,
  • Yoji Fukumoto
  • ,
  • Tomohiro Osaki
  • ,
  • Keigo Ashida
  • ,
  • Yoshiyuki Fujiwara

48
4
開始ページ
395
終了ページ
403
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00595-017-1599-2
出版者・発行元
Springer Tokyo

Purpose: The prognostic nutritional index (PNI) is considered useful for predicting the prognosis of patients with gastric cancer (GC). This retrospective study investigated the relationship between both the pre- and postoperative PNI and the prognosis of GC patients. Methods: The subjects of this study were 254 patients who underwent curative surgery for histopathologically diagnosed GC. Results: Patients were divided according to their pre- and postoperative PNI as follows: preoperative PNI of ≥ 52 (pre-PNIHigh), preoperative PNI of &lt
 52 (pre-PNILow), postoperative PNI of ≥ 49 (post-PNIHigh), and postoperative PNI of &lt
 49 (pre-PNILow). Both pre- and postoperative PNI were significantly associated with GC prognosis. Patients were then divided as follows: group A, patients with pre-PNIHigh and post-PNIHigh
group B, patients with either pre-PNIHigh and post-PNILow or pre-PNILow and post-PNIHigh
and group C, patients with pre-PNILow and post-PNILow. The 5-year survival rates were 100.0, 83.0, and 67.1% for groups A, B, and C, respectively. Multivariate analysis indicated that the combination of pre- and postoperative PNI was an independent prognostic indicator. Conclusions: Combined analysis of the pre- and postoperative PNI offers accurate information about the prognosis of patients with GC.

リンク情報
DOI
https://doi.org/10.1007/s00595-017-1599-2
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29027629
ID情報
  • DOI : 10.1007/s00595-017-1599-2
  • ISSN : 1436-2813
  • ISSN : 0941-1291
  • PubMed ID : 29027629
  • SCOPUS ID : 85031413125

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