古堅彩子 (Ayako Furugen) - マイポータル

基本情報

所属: 慶應義塾大学薬学部准教授（有期）

学位: 博士 (薬科学)(2013年3月北海道大学)

研究者番号: 90767261
J-GLOBAL ID: 201501082207957889
researchmap会員ID: B000247106

研究分野

ライフサイエンス / 医療薬学 /

主要な経歴

2024年4月 - 現在

慶應義塾大学, 薬学部, 准教授（有期）

もっとみる

学歴

委員歴

2022年7月 - 現在

日本薬学会医療薬科学部会, 若手世話人
2023年6月 - 2024年3月

北海道薬剤師会, 学術・情報委員会委員

受賞

2023年

2024年度日本薬学会女性薬学研究者奨励賞

古堅彩子
2019年

2019年度日本薬学会北海道支部奨励賞 (医療系)

古堅彩子
2015年

平成27 年度 Postdoctoral Award, 日本医療薬学会

古堅彩子

論文

100

UPLC–MS/MS Method for Quantifying Non-stimulant ADHD Medications in Human Breast Milk and Plasma: Application in a Lactating Patient Receiving Atomoxetine

Ryoichi Aoyagi, Ayako Furugen, Ayako Nishimura, Takeshi Umazume, Shuhei Ishikawa, Katsuya Narumi, Keisuke Okamoto, Hinata Ueda, Masaki Kobayashi

Journal of Pharmaceutical and Biomedical Analysis 2026年5月査読有り責任著者
Guideline impact on antibiotic use for tooth extraction across facility types in Japan: An interrupted time series analysis using a health insurance claims database

Akira Yamagami, Ryuma Inasaka, Shungo Imai, Masami Tsuchiya, Satoko Hori, Ayako Furugen

Journal of Hospital Infection 2026年2月査読有り最終著者
Placental transfer of third-generation antiepileptic drugs: in vivo lacosamide case study and in vitro investigation of transporter inhibition by lacosamide and perampanel.

Ayami Ueda, Ayako Furugen, Ayako Nishimura, Takeshi Umazume, Ryoichi Aoyagi, Keisuke Okamoto, Katsuya Narumi, Hinata Ueda, Masaki Kobayashi

Journal of pharmaceutical health care and sciences 2026年1月24日査読有り責任著者
Evaluation of intestinal absorption of deoxyribonucleic acid components in salmon milt extract using in-situ and in vitro gastrointestinal absorption models.

Rin Taguchi, Katsuya Narumi, Hinata Ueda, Hiroshi Satoh, Takao Mori, Keisuke Okamoto, Ayako Furugen, Masaki Kobayashi

Bioscience, biotechnology, and biochemistry 2026年1月9日査読有り
授乳期における医薬品の使用実態調査消費者パネルによるインターネット調査

佐山杏子, 祝嶺美里, 山神彰, 堀里子, 古堅彩子

日本医薬品情報学会総会・学術大会講演要旨集 27回 115-115 2025年6月
Analysis of drug transporter expression in syncytiotrophoblast derived from human placental stem cells: Expression and function of efflux transporters.

Riko Sawada, Ayako Furugen, Ayami Ueda, Ayako Nishimura, Takeshi Umazume, Katsuya Narumi, Masaki Kobayashi

Placenta 165 23-32 2025年3月27日査読有り責任著者
Validity and Utility of a Risk Prediction Model for Wound Infection After Lower Third Molar Surgery

Akira Yamagami, Katsuya Narumi, Yoshitaka Saito, Ayako Furugen, Shungo Imai, Keisuke Okamoto, Yoshimasa Kitagawa, Yoichi Ohiro, Ryo Takagi, Yoh Takekuma …

Oral Diseases 2025年1月10日査読有り
Evaluation of the Effect of Aldehyde Oxidase Inhibitors on 6-Mercaptopurine Metabolism.

Hinata Ueda, Katsuya Narumi, Ayako Furugen, Keisuke Okamoto, Yoshitaka Saito, Masaki Kobayashi

Biological & pharmaceutical bulletin 48(5) 713-720 2025年査読有り
Safety Assessment of Medications during Pregnancy and Breastfeeding Based on Quantitative and Toxicological Analyses.

Ayako Furugen

Biological & pharmaceutical bulletin 48(4) 337-343 2025年査読有り招待有り筆頭著者責任著者
Validated UPLC-MS/MS method for quantification of melatonin receptor agonists and dual orexin receptor antagonists in human plasma and breast milk: Application to quantify suvorexant and lemborexant in clinical samples

Hina Ishikawa, Ayako Furugen, Ayako Nishimura, Takeshi Umazume, Shuhei Ishikawa, Ryoichi Aoyagi, Katsuya Narumi, Keisuke Okamoto, Yoh Takekuma, Mitsuru Sugawara …

Journal of Pharmaceutical and Biomedical Analysis 251 116432-116432 2024年12月査読有り責任著者
Effects of famotidine use during pregnancy: an observational cohort study.

Ayako Nishimura, Ayako Furugen, Masaki Kobayashi, Yoh Takekuma, Naho Yakuwa, Mikako Goto, Masahiro Hayashi, Atsuko Murashima, Mitsuru Sugawara

Journal of pharmaceutical health care and sciences 10(1) 70-70 2024年11月8日査読有り
Reply to Accurate Risk Prediction Model for Surgical Site Infection After Lower Third Molar Surgery.

Akira Yamagami, Katsuya Narumi, Yoshitaka Saito, Ayako Furugen, Shungo Imai, Yoshimasa Kitagawa, Yoichi Ohiro, Ryo Takagi, Yoh Takekuma, Mitsuru Sugawara …

Oral diseases 2024年11月3日
Alteration in folate carrier expression via histone deacetylase inhibition in BeWo human placental choriocarcinoma cells.

Yuki Miyazawa, Ayako Furugen, Ryoichi Aoyagi, Haruna Kosugi, Ayako Nishimura, Takeshi Umazume, Katsuya Narumi, Masaki Kobayashi

Toxicology in vitro : an international journal published in association with BIBRA 105934-105934 2024年9月3日査読有り責任著者
Contribution of aldehyde oxidase to methotrexate-induced hepatotoxicity: In Vitro and pharmacoepidemiological approaches.

Ayako Moriyama, Hinata Ueda, Katsuya Narumi, Shuho Asano, Ayako Furugen, Yoshitaka Saito, Masaki Kobayashi

Expert opinion on drug metabolism & toxicology 2024年5月6日査読有り
Monocarboxylate Transporters 1 and 2 Are Responsible for L-Lactate Uptake in Differentiated Human Neuroblastoma SH-SY5Y Cells

Tomoya Sakuma, Yuto Mukai, Atsushi Yamaguchi, Yudai Suganuma, Keisuke Okamoto, Ayako Furugen, Katsuya Narumi, Shuhei Ishikawa, Yoshitaka Saito, Masaki Kobayashi

Biological and Pharmaceutical Bulletin 47(4) 764-770 2024年4月4日査読有り
Breast milk concentrations of acetaminophen and diclofenac - unexpectedly high mammary transfer of the general-purpose drug acetaminophen.

Ryo Tamaki, Kiwamu Noshiro, Ayako Furugen, Ayako Nishimura, Hiroshi Asano, Hidemichi Watari, Masaki Kobayashi, Takeshi Umazume

BMC pregnancy and childbirth 24(1) 90-90 2024年1月29日査読有り
Association Between Multisystem Immune-related Adverse Events and Progression-free Survivals in PD-1/PD-L1 Inhibitor Monotherapy.

Atsushi Yamaguchi, Yoshitaka Saito, Keisuke Okamoto, Ayako Furugen, Katsuya Narumi, Yoh Takekuma, Jun Sakakibara-Konishi, Yasushi Shimizu, Ichiro Kinoshita, Mitsuru Sugawara …

In vivo (Athens, Greece) 38(6) 2886-2896 2024年査読有り
Salmon Milt Extract Suppresses Glucose Uptake by Downregulating SGLT1 and GLUT2 Expression in Caco-2 Cells.

Taichi Sato, Katsuya Narumi, Rin Taguchi, Komei Ishihara, Hiroshi Satoh, Takao Mori, Keisuke Okamoto, Ayako Furugen, Masaki Kobayashi

Biological & pharmaceutical bulletin 47(9) 1477-1483 2024年査読有り
Comparative study on the occurrence of adverse effects in the concomitant use of azathioprine and aldehyde oxidase inhibitors.

Hinata Ueda, Katsuya Narumi, Shuho Asano, Yoshitaka Saito, Ayako Furugen, Masaki Kobayashi

Expert opinion on drug safety 2023年12月14日査読有り
Use of lacosamide for focal epilepsy in a child with kidney failure undergoing peritoneal dialysis.

Yuki Ueda, Ayako Furugen, Masaki Kobayashi, Yasuyuki Sato, Yasuhiro Ueda, Asako Hayashi, Takeru Goto, Shuhei Kimura, Masashi Narugami, Sachiko Nakakubo …

Brain & development 2023年10月30日査読有り