古市達哉 (TATSUYA FURUICHI) - マイポータル

基本情報

所属: 岩手大学農学部共同獣医学科実験動物学研究室教授

学位: 博士（医学）(大阪大学)

J-GLOBAL ID: 201001085951643577
researchmap会員ID: 6000023002

外部リンク: http://news7a1.atm.iwate-u.ac.jp/cgi-bin/list/list.cgi?id=134

研究キーワード

研究分野

経歴

2012年 - 現在

岩手大学農学部共同獣医学科実験動物学研究室
2010年 - 2012年

東京慈恵会医科大学実験動物研究施設
2004年 - 2010年

理化学研究所脳科学総合研究センター／ゲノム医科学研究センター
2000年 - 2004年

大阪大学大学院医学系研究科分子病態内科学講座
1992年 - 2000年

中外製薬創薬開発研究所

学歴

2005年1月

博士 (医学）（大阪大学、論文博士）
1986年4月 - 1992年3月

北海道大学, 獣医学部

主要な委員歴

もっとみる

論文

Mice lacking nucleotide sugar transporter SLC35A3 exhibit lethal chondrodysplasia with vertebral anomalies and impaired glycosaminoglycan biosynthesis.

Soichiro Saito, Shuji Mizumoto, Tsukasa Yonekura, Rina Yamashita, Kenta Nakano, Tadashi Okubo, Shuhei Yamada, Tadashi Okamura, Tatsuya Furuichi

PloS one 18(4) e0284292 2023年
CANT1 deficiency in a mouse model of Desbuquois dysplasia impairs glycosaminoglycan synthesis and chondrocyte differentiation in growth plate cartilage.

Kazuki Kodama, Hiroaki Takahashi, Nobuyasu Oiji, Kenta Nakano, Tadashi Okamura, Kimie Niimi, Eiki Takahashi, Long Guo, Shiro Ikegawa, Tatsuya Furuichi

FEBS Open Bio 10(6) 1096-1103 2020年6月査読有り責任著者
Crim1C140S mutant mice reveal the importance of cysteine 140 in the internal region 1 of CRIM1 for its physiological functions.

Tatsuya Furuichi, Manami Tsukamoto, Masaki Saito, Yuriko Sato, Nobuyasu Oiji, Kazuhiro Yagami, Ryutaro Fukumura, Yoichi Gondo, Long Guo, Shiro Ikegawa, Yu Yamamori, Kentaro Tomii

Mammalian Genome : official journal of the International Mammalian Genome Society 30(11-12) 329-338 2019年12月査読有り筆頭著者責任著者
Disruption of the mouse Slc39a14 gene encoding zinc transporter ZIP14 is associated with decreased bone mass, likely caused by enhanced bone resorption.

Sun Sasaki, Manami Tsukamoto, Masaki Saito, Shintaro Hojyo, Toshiyuki Fukada, Masamichi Takami, Tatsuya Furuichi

FEBS Open Bio 8(4) 655-663 2018年4月査読有り責任著者
An ENU-induced p.C225S missense mutation in the mouse Tgfb1 gene does not cause Camurati-Engelmann disease-like skeletal phenotypes

Satoki Ichimura, Shun Sasaki, Takuya Murata, Ryutaro Fukumura, Yoichi Gondo, Shiro Ikegawa, Tatsuya Furuichi

EXPERIMENTAL ANIMALS 66(2) 137-144 2017年4月査読有り責任著者
Overexpression of BCLXL in Osteoblasts Inhibits Osteoblast Apoptosis and Increases Bone Volume and Strength

Takeshi Moriishi, Ryo Fukuyama, Toshihiro Miyazaki, Tatsuya Furuichi, Masako Ito, Toshihisa Komori

JOURNAL OF BONE AND MINERAL RESEARCH 31(7) 1366-1380 2016年7月査読有り
Endoplasmic reticulum stress-mediated apoptosis contributes to a skeletal dysplasia resembling platyspondylic lethal skeletal dysplasia, Torrance type, in a novel Col2a1 mutant mouse line

Makoto Kimura, Satoki Ichimura, Kuniaki Sasaki, Hiroshi Masuya, Tomohiro Suzuki, Shigeharu Wakana, Shiro Ikegawa, Tatsuya Furuichi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 468(1-2) 86-91 2015年12月査読有り責任著者
[Collagen abnormalities and endoplasmic reticulum stress in bone and cartilage].

Furuichi T, Nishimura G, Ikegawa S

Clinical Calcium 23(11) 1635-1640 2013年11月査読有り筆頭著者責任著者
Zinc signal: a new player in osteobiology

Toshiyuki Fukada, Shintaro Hojyo, Tatsuya Furuichi

JOURNAL OF BONE AND MINERAL METABOLISM 31(2) 129-135 2013年3月査読有り
SP7 Inhibits Osteoblast Differentiation at a Late Stage in Mice

Carolina A. Yoshida, Hisato Komori, Zenjiro Maruyama, Toshihiro Miyazaki, Keishi Kawasaki, Tatsuya Furuichi, Ryo Fukuyama, Masako Mori, Kei Yamana, Kouhei Nakamura, Wenguang Liu, Satoru Toyosawa, Takeshi Moriishi, Hiroshi Kawaguchi, Kenji Takada, Toshihisa Komori

PLOS ONE 7(3) E32364 2012年3月
Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis

Takeshi Moriishi, Zenjiro Maruyama, Ryo Fukuyama, Masako Ito, Toshihiro Miyazaki, Hideki Kitaura, Hidetake Ohnishi, Tatsuya Furuichi, Yosuke Kawai, Ritsuko Masuyama, Hisato Komori, Kenji Takada, Hiroshi Kawaguchi, Toshihisa Komori

PLOS ONE 6(11) e27487 2011年11月
ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type

Tatsuya Furuichi, Hiroshi Masuya, Tomohiko Murakami, Keiichiro Nishida, Gen Nishimura, Tomohiro Suzuki, Kazunori Imaizumi, Takashi Kudo, Kiyoshi Ohkawa, Shigeharu Wakana, Shiro Ikegawa

MAMMALIAN GENOME 22(5-6) 318-328 2011年6月筆頭著者責任著者
A founder mutation of CANT1 common in Korean and Japanese Desbuquois dysplasia

Jin Dai, Ok-Hwa Kim, Tae-Joon Cho, Noriko Miyake, Hae-Ryong Song, Tatsuki Karasugi, Satoru Sakazume, Masahide Ikema, Yoshito Matsui, Toshiro Nagai, Naomichi Matsumoto, Hirofumi Ohashi, Naoyuki Kamatani, Gen Nishimura, Tatsuya Furuichi, Atsushi Takahashi, Shiro Ikegawa

JOURNAL OF HUMAN GENETICS 56(5) 398-400 2011年5月
Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development

Yan Geng, Yingying Dong, Mingyan Yu, Long Zhang, Xiaohua Yan, Jingxia Sun, Long Qiao, Huixia Geng, Masahiro Nakajima, Tatsuya Furuichi, Shiro Ikegawa, Xiang Gao, Ye-Guang Chen, Dianhua Jiang, Wen Ning

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 108(17) 7058-7063 2011年4月
CANT1 mutation is also responsible for Desbuquois dysplasia, type 2 and Kim variant

Tatsuya Furuichi, Jin Dai, Tae-Joon Cho, Satoru Sakazume, Masahide Ikema, Yoshito Matsui, Gareth Baynam, Toshiro Nagai, Noriko Miyake, Naomichi Matsumoto, Hirofumi Ohashi, Sheila Unger, Andrea Superti-Furga, Ok-Hwa Kim, Gen Nishimura, Shiro Ikegawa

JOURNAL OF MEDICAL GENETICS 48(1) 32-37 2011年1月
SMOC1 Is Essential for Ocular and Limb Development in Humans and Mice

Ippei Okada, Haruka Hamanoue, Koji Terada, Takaya Tohma, Andre Megarbane, Eliane Chouery, Joelle Abou-Ghoch, Nadine Jalkh, Ozgur Cogulu, Ferda Ozkinay, Kyoji Horie, Junji Takeda, Tatsuya Furuichi, Shiro Ikegawa, Kiyomi Nishiyama, Satoko Miyatake, Akira Nishimura, Takeshi Mizuguchi, Norio Niikawa, Fumiki Hirahara, Tadashi Kaname, Koh-ichiro Yoshiura, Yoshinori Tsurusaki, Hiroshi Doi, Noriko Miyake, Takahisa Furukawa, Naomichi Matsumoto, Hirotomo Saitsu

AMERICAN JOURNAL OF HUMAN GENETICS 88(1) 30-41 2011年1月
Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development

Yumi Watanabe, Kosei Takeuchi, Susumu Higa Onaga, Michiko Sato, Mika Tsujita, Manabu Abe, Rie Natsume, Minqi Li, Tatsuya Furuichi, Mika Saeki, Tomomi Izumikawa, Ayumi Hasegawa, Minesuke Yokoyama, Shiro Ikegawa, Kenji Sakimura, Norio Amizuka, Hiroshi Kitagawa, Michihiro Igarashi

BIOCHEMICAL JOURNAL 432(1) 47-55 2010年11月
Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family

J. Dai, O-H Kim, T-J Cho, M. Schmidt-Rimpler, H. Tonoki, K. Takikawa, N. Haga, K. Miyoshi, H. Kitoh, W-J Yoo, I-H Choi, H-R Song, D-K Jin, H-T Kim, H. Kamasaki, P. Bianchi, G. Grigelioniene, S. Nampoothiri, M. Minagawa, S-i Miyagawa, T. Fukao, C. Marcelis, M. C. E. Jansweijer, R. C. M. Hennekam, F. Bedeschi, A. Mustonen, Q. Jiang, H. Ohashi, T. Furuichi, S. Unger, B. Zabel, E. Lausch, A. Superti-Furga, G. Nishimura, S. Ikegawa

JOURNAL OF MEDICAL GENETICS 47(10) 704-709 2010年10月
Loss-of-Function Mutations of CHST14 in a New Type of Ehlers-Danlos Syndrome

Noriko Miyake, Tomoki Kosho, Shuji Mizumoto, Tatsuya Furuichi, Atsushi Hatamochi, Yoji Nagashima, Eiichi Arai, Kazuo Takahashi, Rie Kawamura, Keiko Wakui, Jun Takahashi, Hiroyuki Kato, Hiroshi Yasui, Tadao Ishida, Hirofumi Ohashi, Gen Nishimura, Masaaki Shiina, Hirotomo Saitsu, Yoshinori Tsurusaki, Hiroshi Doi, Yoshimitsu Fukushima, Shiro Ikegawa, Shuhei Yamada, Kazuyuki Sugahara, Naomichi Matsumoto

HUMAN MUTATION 31(8) 966-974 2010年8月
A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

Yuta Kochi, Yukinori Okada, Akari Suzuki, Katsunori Ikari, Chikashi Terao, Atsushi Takahashi, Keiko Yamazaki, Naoya Hosono, Keiko Myouzen, Tatsuhiko Tsunoda, Naoyuki Kamatani, Tatsuya Furuichi, Shiro Ikegawa, Koichiro Ohmura, Tsuneyo Mimori, Fumihiko Matsuda, Takuji Iwamoto, Shigeki Momohara, Hisashi Yamanaka, Ryo Yamada, Michiaki Kubo, Yusuke Nakamura, Kazuhiko Yamamoto

NATURE GENETICS 42(6) 515-U63 2010年6月