論文

査読有り
1997年9月

Preparation of peptide thioesters using Fmoc-solid-phase peptide synthesis and its application to the construction of a template-assembled synthetic protein (TASP)

TETRAHEDRON LETTERS
  • S Futaki
  • ,
  • K Sogawa
  • ,
  • J Maruyama
  • ,
  • T Asahara
  • ,
  • M Niwa
  • ,
  • H Hojo

38
35
開始ページ
6237
終了ページ
6240
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/S0040-4039(97)01434-2
出版者・発行元
PERGAMON-ELSEVIER SCIENCE LTD

Preparation of peptide thioesters was conducted through peptide chain construction with Fmoc-solid-phase peptide synthesis on a 2-chlorotrityl resin followed by coupling with HS-(CH2)(2)-COOEt and deprotection with 95% aqueous CF3COOH. The peptide thioester corresponding to a transmembrane segment of he calcium channel (S4 in repeat IV) thus obtained was introduced onto a peptide template to give an artificial four-helix-bundle protein. (C) 1997 Elsevier Science Ltd.

リンク情報
DOI
https://doi.org/10.1016/S0040-4039(97)01434-2
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:A1997XT72400034&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/S0040-4039(97)01434-2
  • ISSN : 0040-4039
  • Web of Science ID : WOS:A1997XT72400034

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