Masahiro Ito

J-GLOBAL         Last updated: Apr 10, 2019 at 12:51
 
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Name
Masahiro Ito
Affiliation
Toyo University
Section
Faculty of Life Sciences
Research funding number
80297738
ORCID ID
orcid.org/0000-0002-4976-762X

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
Apr 2009
 - 
Today
Professor, Factory of Life Sciences, Toyo University
 
Apr 2001
 - 
Mar 2009
Associate professor, Factory of Life Sciences, Toyo University
 
Apr 1997
 - 
Mar 2001
Lecturer, Factory of Life Sciences, Toyo University
 
Apr 1994
 - 
Mar 1997
postdoctoral researcher, Department of Biochemistry, Mount Sinai School of Medicine
 

Committee Memberships

 
2015
 - 
Today
Applied and Environmental Microbiology  Editorial Board Member
 
Apr 2013
 - 
Today
Center for Academic Research Promotion  Deputy-Directors
 
Jan 2013
 - 
Today
Japanese Society for Extremophiles  General affairs secretary
 
Aug 2008
 - 
Jul 2010
Ministry of Education, Culture, Sports, Science and Technology (MEXT)  Program officer
 

Awards & Honors

 
Dec 2016
Elucidation ion selectivity and identification of ion transport subunits in the Mrp type antiporter, Young Scientist Poster Award (1st), The 1st international Conference on Applied Microbiology in Vietnam
Winner: Mitsue Matsui, Masahiro Ito
 
Nov 2015
A functional analysis of stator complex of flagellar motor from Bacillus trypoxylicola, Poster award, The 16th Annual Meeting of the Japanese society for Extremophiles
Winner: Riku Imazawa, Shun Naganawa, Masahiro Ito
 
Dec 2014
Elucidation of the differences in Na+ affinity in a neutral pH environment of the Na+-driven stator MotPS in alkaliphilic Bacillus pseudofirmus OF4 and Bacillus subtilis, Poster award, The 15th Annual Meeting of the Japanese society for Extremophiles
Winner: Yuka Takahashi, Yukina Noguchi, Masahiro Ito
 
Nov 2014
Identification for a factor affecting of stimulation of motility in Methylobacterium sp. 121, Poster award, The 15th Annual Meeting of the Japanese society for Extremophiles
Winner: Wakabayashi Yuu, Tetsu Shimizu, Akira Nakamura, Masahiro Ito
 
Sep 2014
The clarification of the differences between alkaliphilic and neutralophilic Bacillus influx control of Na+ near neutral pH in the Na+-driven flagellar motor stator MotPS, ISE Young Scientist Poster Award, International Congress on Extremophiles 2014
Winner: Yuka Taakahashi, Yukina Noguchi, Masahiro Ito
 
Mar 2013
Analytical results of microbiological diversity in the seismogenic zone (Japan trench) sediment at 3 months and 17 months after Tohoku Region Pacific Offshore Earthquake occurred, Young Scientist Poster Award, Blue Earth 2013 (JAMSTEC)
Winner: Sayumi Kinoshita, Masahiro Ito, et al.
 
Nov 2012
Elucidation of rotation mechanism of hybrid biomotor that can utilize two types of coupling ions, Poster award, The 2012 Annual Meeting of the Kanto Branch of the Japan Society for Bioscience, Biotechnology, and Agrochemistry
Winner: Yuka Takahashi, Masahiro Ito
 
Jun 2012
Research on Hybrid Bacterial Flagellar Motor, Inoue Enryo Prize, Toyo University
 
Nov 2011
A novel K+-stimulated flagellar motor from alkaliphilic Bacillus alcalophilus., Poster award, The 12th Annual Meeting of the Japanese society for Extremophiles
Winner: Motohiko Sano, Naoya Terahara, Masahiro Ito
 
Oct 2011
Identification of amino acid residues in the flagellar stator involved in the reduction of motility under the neutral environment of the alkalophilic Bacillus pseudofirmus OF4, Poster award, The 2011 Annual Meeting of the Kanto Branch of the Japan Society for Bioscience, Biotechnology, and Agrochemistry
Winner: Yukina Noguchi, Masahiro Ito
 
Mar 2011
Properties of Bacterial Flagellar Motor Powered by Hybrid Stators, JSPS Prize, the Japan Society for the Promotion of Science
 
Nov 2009
Identification and characterization of functional residues in a Multi-subunit type Na+/H+ antiporter Mrp complex from alkaliphilic Bacillus pseudofirmus OF4., Poster award, The 10th Annual Meeting of the Japanese society for Extremophiles
Winner: Masato Morino, Shinsuke Natsui, Tomohiro Ono, Talia H. Swartz, Terry A. Krulwich, Masahiro Ito
 
Oct 2009
Identification and analysis of amino acid residues important for the rotation mechanism of flagellar stator MotAB, MotPS of Bacillus subtilis, Poster award, The 10th Annual Meeting of the Japanese society for Extremophiles
Winner: Yuka Takahashi, Naoya Terahara, Sachiyo Koizumi, Masahiro Ito
 
Nov 2008
A conversion of the coupling ion specificity of stators in a Bacillus flagellar motor, Poster award, The 9th Annual Meeting of the Japanese society for Extremophiles
Winner: Naoya Terahara, Terry Ann Krulwich, Masahiro Ito
 
Jun 2008
A flagellarstator MotAB from alkaliphilic Bacillus clausii can utilize two types of ions as coupling ions, Outstanding performance award(Oral presentation), The 3rd Japan transporter research association
Winner: Naoya Terahara, Masahiro Ito
 
Nov 2007
Bacillus subtilis flagellar motor is a hybrid motor that can utilize two kinds of energy, Young Scientist Award (oral presentation), Kanto Branch meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry
Winner: Naoya Terahara,Masahiro Ito
 
Nov 2007
The visualization of the voltage-gated Na+ channel of Alkaliphilic Bacillus pseudofirmus OF4 by using fluorescent protein fusion., Poster award, The 8th Annual Meeting of the Japanese society for Extremophiles
Winner: Shun Fujinami, Masahiro Ito
 
Nov 2005
Young Scientist Award, the Japan Society for Extremophiles
 
Nov 2004
Poster award, The 5th Annual Meeting of the Japanese society for Extremophiles
Winner: Shun Fujinami, Masahiro Ito
 
Sep 2002
ISE Award, International Society for Extremophiles (ISE)
 

Published Papers

 
A Hydrophobic Small Protein, BpOF4_01690, Is Critical for Alkaliphily of Alkaliphilic Bacillus pseudofirmus OF4
Tetsuaki Takahashi, Terry Ann Krulwich, Masahiro Ito
Frontiers in Microbiology   9 1994   Aug 2018   [Refereed]
The Surface Layer Homology Domain-Containing Proteins of Alkaliphilic Bacillus pseudofirmus OF4 Play an Important Role in Alkaline Adaptation via Peptidoglycan Synthesis.
Masahiro Ito
Frontiers in Microbiology   9 810   May 2018   [Refereed]
Masahiro Ito, Masato Morino, Terry Ann Krulwich
Frontiers in Microbiology   8 2328   Nov 2017   [Refereed]
Ion Selectivity of the Flagellar Motors Derived from the Alkaliphilic Bacillus and Paenibacillus Species
Yuka Takahashi, Masahiro Ito
Methods in Molecular Biology   1593 297-303   Apr 2017   [Refereed][Invited]
Load-and polysaccharide-dependent activation of the Na+-type MotPS stator in the Bacillus subtilis flagellar motor.
Terahara, N., Noguchi, Y., Nakamura, S., Kamiike, N., Ito, M., Namba, K., Minamino, T.
Scientific Reports   7 e46081   Apr 2017   [Refereed]
Ito M, Takahashi Y
Extremophiles   21(1) 3-14   Jan 2017   [Refereed]
Morino M, Ogoda S, Krulwich TA, Ito M
Extremophiles   21(1) 51-64   Jan 2017   [Refereed]
Riku Imazawa, Yuka Takahashi, Motohiko Sano, Wataru Aoki, Masahiro Ito
Scientific Reports   6 e19773-g0000197042   Jan 2016   [Refereed]
The bacterial flagellar motor is a sophisticated nanomachine embedded in the cell envelope and powered by an electrochemical gradient of H+, Na+, or K+across the cytoplasmic membrane. Here we describe a new member of the bacterial flagellar stator...
Draft Genome Sequence of Methylobacterium sp. ME121, isolated from soil as a mixed single colony with Kaistia sp. 32K
Fujinami S, Takeda-Yano K, Onodera T, Satoh K, Shimizu T, Wakabayashi Y, Narumi I, Nakamura A, Ito M
Genome Announcements   3(5) e01005-15   Sep 2015   [Refereed]
Fujinami S, Oikawa Y, Araki T, Shinmura Y, Midorikawa R, Ishizaka H, Kato C, Horikoshi K, Ito M, and Tamegai H.
Genome Announcements   2(6) e01313-14   Dec 2014   [Refereed]
DeCaen PG, Takahashi Y, Krulwich TA, Ito M, Clapham DE.
eLife   3 e04387   Nov 2014   [Refereed]
Attie O, Jayaprakash A, Shah H, Paulsen IT, Morino M, Takahashi Y, Narumi I, Sachidanandam R, Satoh K, Ito M, and Krulwichc TA.
Genome Announcements   2(6) e01175-14   Nov 2014   [Refereed]
Takahashi Y., Koyama K., Ito M.
Journal of General and Applied Microbiology   60(4) 131-139   Oct 2014   [Refereed]
Fujinami S, Takeda-Yano K, Onodera T, Satoh K, Sano M, Takahashi Y, Narumi I, Ito M.
Genome Announcements   2(5) e00866-14   Sep 2014   [Refereed]
Fujinami S., Takeda K., Onodera T., Satoh S., Sano M., Narumi I., Ito M.
Genome Announcements   2(3) e00458-14   May 2014   [Refereed]
Yuka Takahashi, Masahiro Ito
Journal of Biochemistry   156(4) 211-220   Apr 2014   [Refereed]
Morino M, Suzuki T, Ito M, Krulwich TA
Journal of bacteriology   196 28-35   Jan 2014   [Refereed]
Fujinami S, Takeda K, Onodera T, Satoh K, Sano M, Narumi I, Ito M
Genome announcements   1    Dec 2013   [Refereed]
Morino M, Ito M
FEMS microbiology letters   335 26-30   Oct 2012   [Refereed]
Janto B, Ahmed A, Ito M, Liu J, Hicks DB, Pagni S, Fackelmayer OJ, Smith TA, Earl J, Elbourne LD, Hassan K, Paulsen IT, Kolstø AB, Tourasse NJ, Ehrlich GD, Boissy R, Ivey DM, Li G, Xue Y, Ma Y, Hu FZ, Krulwich TA
Environmental microbiology   13 3289-3309   Dec 2011   [Refereed]
Fujinami S, Sato T, Ito M
Extremophiles : life under extreme conditions   15 587-596   Sep 2011   [Refereed]
Fujinami S, Terahara N, Krulwich TA, Ito M
Future microbiology   4 1137-1149   Nov 2009   [Refereed]
Krulwich TA, Hicks DB, Ito M
Molecular microbiology   74 257-260   Oct 2009   [Refereed]
Fujisawa M, Wada Y, Tsuchiya T, Ito M
Archives of microbiology   191 649-657   Aug 2009   [Refereed]
Terahara N, Krulwich TA, Ito M
Proceedings of the National Academy of Sciences of the United States of America   105 14359-14364   Sep 2008   [Refereed]
Morino M, Natsui S, Swartz TH, Krulwich TA, Ito M
Journal of bacteriology   190 4162-4172   Jun 2008   [Refereed]
Fujinami S, Sato T, Trimmer JS, Spiller BW, Clapham DE, Krulwich TA, Kawagishi I, Ito M
Microbiology (Reading, England)   153 4027-4038   Dec 2007   [Refereed]
Fujisawa M, Ito M, Krulwich TA
Proceedings of the National Academy of Sciences of the United States of America   104 13289-13294   Aug 2007   [Refereed]
Swartz TH, Ito M, Ohira T, Natsui S, Hicks DB, Krulwich TA
Journal of bacteriology   189 3081-3090   Apr 2007   [Refereed]
Terahara N, Fujisawa M, Powers B, Henkin TM, Krulwich TA, Ito M
Journal of bacteriology   188 2701-2705   Apr 2006   [Refereed]
Liu J, Xue Y, Wang Q, Wei Y, Swartz TH, Hicks DB, Ito M, Ma Y, Krulwich TA
Journal of bacteriology   187 7589-7595   Nov 2005   [Refereed]
Swartz TH, Ikewada S, Ishikawa O, Ito M, Krulwich TA
Extremophiles : life under extreme conditions   9 345-354   Oct 2005   [Refereed]
Fujisawa M, Kusumoto A, Wada Y, Tsuchiya T, Ito M
Archives of microbiology   183 411-420   Sep 2005   [Refereed]
Ito M, Terahara N, Fujinami S, Krulwich TA
Journal of molecular biology   352 396-408   Sep 2005   [Refereed]
Ito M, Hicks DB, Henkin TM, Guffanti AA, Powers BD, Zvi L, Uematsu K, Krulwich TA
Molecular microbiology   53 1035-1049   Aug 2004   [Refereed]
Ito M, Xu H, Guffanti AA, Wei Y, Zvi L, Clapham DE, Krulwich TA
Proceedings of the National Academy of Sciences of the United States of America   101 10566-10571   Jul 2004   [Refereed]
Fujisawa M, Wada Y, Ito M
FEMS microbiology letters   231 211-217   Feb 2004   [Refereed]
Wei Y, Southworth TW, Kloster H, Ito M, Guffanti AA, Moir A, Krulwich TA
Journal of bacteriology   185 5133-5147   Sep 2003   [Refereed]
Ito M, Aono R
Bioscience, biotechnology, and biochemistry   66 218-220   Jan 2002   [Refereed]

Misc

 
Masahiro Ito
kagaku to seibutsu   55(4) 240-241   Mar 2017   [Refereed][Invited]
Yuka Takahashi, Masahiro Ito
Nihon nyusankin gakkai shi   25(3) 177-177   Nov 2014   [Refereed][Invited]
ITO Masahiro
Cryobiology and cryotechnology   57(1) 25-32   Apr 2011
Alkaliphiles, which are capable of growth in an extremely alkaline environment, serve as a model system to understand the physiological mechanisms allowing microbial growth under extreme environmental conditions. The internal pH of alkaliphiles is...
TERAHARA Naoya, ITO Masahiro
Bioscience & industry   66(7) 366-368   Jul 2008
FUJISAWA Makoto, ITO Masahiro
Bioscience & industry   66(6) 300-302   Jun 2008
ITOH Masahiro
Biophysics   46(1) 20-25   Jan 2006
In alkaliphilic Bacillus, Na^+-dependent pH homeostasis involves antiport activities as well as Na^+ re-entry routes. MotPS that are homologous to MotAB are required for the Na^+-dependent motility of alkaliphilic B. pseudofirmus OF4. Purified and...

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2005 - 2007    Investigator(s): Masahiro ITO
The bacterial ion channels are useful for the structural analysis of the eukaryotic ion channels. The elucidation of physiologic functions and effecter proteins of the bacterial ion channels is important in research of the ion channels. NavBP is t...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2009 - 2012    Investigator(s): Masahiro ITO
At first, we identified that the flagellar motor of B. subtilis was a hybrid motor and it rotated by using both ion motive forces, H+ and Na+, by a single molecular mechanism. Next, the critical charged amino acid residues between the second and t...