Masahiro Ito

J-GLOBAL         Last updated: Mar 23, 2017 at 01:21
Masahiro Ito
Toyo University
Faculty of Life Sciences
Research funding number

Research Interests


Research Areas


Academic & Professional Experience

Apr 2009
Professor, Factory of Life Sciences, Toyo University
Apr 2001
Mar 2009
Associate professor, Factory of Life Sciences, Toyo University
Apr 1997
Mar 2001
Lecturer, Factory of Life Sciences, Toyo University
Apr 1994
Mar 1997
postdoctoral researcher, Department of Biochemistry, Mount Sinai School of Medicine

Committee Memberships

Applied and Environmental Microbiology  Editorial Board Member
Apr 2013
Center for Academic Research Promotion  Deputy-Directors
Jan 2013
Japanese Society for Extremophiles  General affairs secretary
Aug 2008
Jul 2010
Ministry of Education, Culture, Sports, Science and Technology (MEXT)  Program officer

Awards & Honors

Jun 2012
Inoue Enryo Prize, Toyo University
Mar 2011
JSPS Prize, the Japan Society for the Promotion of Science
Nov 2005
Young Scientist Award, the Japan Society for Extremophiles
Sep 2002
ISE Award, International Society for Extremophiles (ISE)

Published Papers

Load-and polysaccharide-dependent activation of the Na+-type MotPS stator in the Bacillus subtilis flagellar motor.
Terahara, N., Noguchi, Y., Nakamura, S., Kamiike, N., Ito, M., Namba, K., Minamino, T.
Scientific Reports      Apr 2017   [Refereed]
Nonconventional cation-coupled flagellar motors derived from the alkaliphilic Bacillus and Paenibacillus species
Ito M, Takahashi Y
Extremophiles   21(1) 3-14   Jan 2017   [Refereed]
Differences in the phenotypic effects of mutations in homologous MrpA and MrpD subunits of the multi-subunit Mrp-type Na+/H+ antiporter
Morino M, Ogoda S, Krulwich TA, Ito M
Extremophiles   21(1) 51-64   Jan 2017   [Refereed]
Chapter 24, Ion Selectivity of the Flagellar Motors Derived from the Alkaliphilic Bacillus and Paenibacillus species, The Bacterial Flagellum: Methods and Protocols 
Takahashi Y, Ito M
Methods in Molecular Biology   -g0000197042   2017   [Refereed]
Riku Imazawa, Yuka Takahashi, Motohiko Sano, Wataru Aoki, Masahiro Ito
Scientific Reports   6 e19773-g0000197042   Jan 2016   [Refereed]
The bacterial flagellar motor is a sophisticated nanomachine embedded in the cell envelope and powered by an electrochemical gradient of H+, Na+, or K+across the cytoplasmic membrane. Here we describe a new member of the bacterial flagellar stator...


Masahiro Ito
kagaku to seibutsu   55(4) 240-241   Mar 2017   [Refereed][Invited]
Yuka Takahashi, Masahiro Ito
Nihon nyusankin gakkai shi   25(3) 177-177   Nov 2014   [Refereed][Invited]
ITO Masahiro
Cryobiology and cryotechnology   57(1) 25-32   Apr 2011
Alkaliphiles, which are capable of growth in an extremely alkaline environment, serve as a model system to understand the physiological mechanisms allowing microbial growth under extreme environmental conditions. The internal pH of alkaliphiles is...
TERAHARA Naoya, ITO Masahiro
Bioscience & industry   66(7) 366-368   Jul 2008
FUJISAWA Makoto, ITO Masahiro
Bioscience & industry   66(6) 300-302   Jun 2008
ITOH Masahiro
Biophysics   46(1) 20-25   Jan 2006
In alkaliphilic Bacillus, Na^+-dependent pH homeostasis involves antiport activities as well as Na^+ re-entry routes. MotPS that are homologous to MotAB are required for the Na^+-dependent motility of alkaliphilic B. pseudofirmus OF4. Purified and...

Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2005 - 2007    Investigator(s): Masahiro ITO
The bacterial ion channels are useful for the structural analysis of the eukaryotic ion channels. The elucidation of physiologic functions and effecter proteins of the bacterial ion channels is important in research of the ion channels. NavBP is t...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2009 - 2012    Investigator(s): Masahiro ITO
At first, we identified that the flagellar motor of B. subtilis was a hybrid motor and it rotated by using both ion motive forces, H+ and Na+, by a single molecular mechanism. Next, the critical charged amino acid residues between the second and t...