Toru Mizuki

Profile Information

Affiliation: Toyo University

Degree: 博士（工学）

Researcher number: 80408997
J-GLOBAL ID: 201301082909176546
researchmap Member ID: B000233206

External link: http://kaken.nii.ac.jp/d/r/80408997.ja.html

I have received my phD from Toyo University in 2004. I had researched on enzymes from Extremophiles that live in extreme environments such as high or low temperature, acidity or alkalinity, high pressure and so on. My current research interests include bio-nano fusion research such as increase enzyme activity using a rotational magnetic field and development of new materials using a rare sugar for application in biological field.

Research Areas

Papers

Biological Synthesis of Bioactive Gold Nanoparticles from Inonotus obliquus for Dual Chemo-Photothermal Effects against Human Brain Cancer Cells

Ibrohimjon Shukurov, Mohamed Sheikh Mohamed, Toru Mizuki, Vivekanandan Palaninathan, Tomofumi Ukai, Tatsuro Hanajiri, Toru Maekawa

International Journal of Molecular Sciences, 23(4) 2292-2292, Feb 18, 2022
Scaffold mediated delivery of dual miRNAs to transdifferentiate cardiac fibroblasts

Priyadharshni Muniyandi, Vivekanandan Palaninathan, Toru Mizuki, M. Sheikh Mohamed, Tatsuro Hanajiri, Toru Maekawa

Materials Science and Engineering: C, 128 112323-112323, Sep, 2021
Isolation and cultivation of a novel sulfate-reducing magnetotactic bacterium belonging to the genus Desulfovibrio

Hirokazu Shimoshige, Hideki Kobayashi, Shigeru Shimamura, Toru Mizuki, Akira Inoue, Toru Maekawa

PLOS ONE, 16(3) e0248313-e0248313, Mar 11, 2021
Poly(lactic-co-glycolic acid)/Polyethylenimine Nanocarriers for Direct Genetic Reprogramming of MicroRNA Targeting Cardiac Fibroblasts

Priyadharshni Muniyandi, Vivekanandan Palaninathan, Toru Mizuki, Toru Maekawa, Tatsuro Hanajiri, M. Sheikh Mohamed

ACS Applied Nano Materials, 3(3) 2491-2505, Mar 3, 2020 Peer-reviewed
Chlorotoxin modified morusin-PLGA nanoparticles for targeted glioblastoma therapy.

Srishti Agarwal, M Sheikh Mohamed, Toru Mizuki, Toru Maekawa, D Sakthi Kumar

Journal of materials chemistry. B, 7(39) 5896-5919, Oct 9, 2019 Peer-reviewed
Chemical synthesis and cytotoxicity of neo-glycolipids; rare sugar-glycerol-lipid compounds.

Keisuke Hirata, Takashi Uchida, Yoshikata Nakajima, Toru Maekawa, Toru Mizuki

Heliyon, 4(10) e00861, Oct, 2018
Detection and Analysis of Targeted Biological Cells by Electrophoretic Coulter Method.

Yoshikata Nakajima, Tomofumi Ukai, Toshiaki Shimizu, Kazuhei Ogata, Seiki Iwai, Naohiro Takahashi, Atsushi Aki, Toru Mizuki, Toru Maekawa, Tatsuro Hanajiri

Analytical chemistry, 89(22) 12450-12457, Nov 21, 2017 Peer-reviewed
Formation of core-shell nanoparticles composed of magnetite and samarium oxide in Magnetospirillum magneticum strain RSS-1

Shimoshige, H., Nakajima, Y., Kobayashi, H., Yanagisawa, K., Nagaoka, Y., Shimamura, S., Mizuki, T., Inoue, A., Maekawa, T.

PLoS ONE, 12(1) e0170932, 2017
Synthesis of nanoparticles composed of silver and silver chloride for a plasmonic photocatalyst using an extract from a weed Solidago altissima (goldenrod)

Vemu Anil Kumar, Takashi Uchida, Toru Mizuki, Yoshikata Nakajima, Yoshihiro Katsube, Tatsuro Hanajiri, Toru Maekawa

ADVANCES IN NATURAL SCIENCES-NANOSCIENCE AND NANOTECHNOLOGY, 7(1), Mar, 2016
Synthesis of nanoparticles composed of silver and silver chloride for a plasmonic photocatalyst using an extract from a weed Solidago altissima (goldenrod)

Kumar, V.A., Uchida, T., Mizuki, T., Nakajima, Y., Katsube, Y., Hanajiri, T., Maekawa, T.

Advances in Natural Sciences: Nanoscience and Nanotechnology, 7(1), 2016 Peer-reviewed
Efficient DNA ligation by selective heating of DNA ligase with a radio frequency alternating magnetic field

Suzuki, M., Hayashi, H., Mizuki, T., Maekawa, T., Morimoto, H.

Biochemistry and Biophysics Reports, 8 360-364, 2016
Strategist PLGA Nano-capsules to Deliver siRNA for Inhibition of Carcinoma and Neuroblastoma Cell Lines by Knockdown of MYC Proto-oncogene using CPPs and PNA

Archana Raichur, Yoshikata Nakajima, Yutaka Nagaoka, Kotaro Matsumoto, Toru Mizuki, Kazunori Kato, Toru Maekawa, D. Sakthi Kumar

NanoWorld Journal, 1(2) 32-45, Apr, 2015 Peer-reviewed
Extremophilic polysaccharide nanoparticles for cancer nanotherapy and evaluation of antioxidant properties

Raveendran, S., Palaninathan, V., Nagaoka, Y., Fukuda, T., Iwai, S., Higashi, T., Mizuki, T., Sakamoto, Y., Mohanan, P.V., Maekawa, T. …

International Journal of Biological Macromolecules, 76 310-9, 2015
Encouragement of enzyme reaction utilizing heat generation from ferromagnetic particles subjected to an AC magnetic field

Suzuki, M., Aki, A., Mizuki, T., Maekawa, T., Usami, R., Morimoto, H.

PLoS ONE, 10(5) e0127673, 2015
Effect of polyethylene glycol on the formation of magnetic nanoparticles synthesized by Magnetospirillum magnetotacticum MS-1

Shimoshige, H., Kobayashi, H., Mizuki, T., Nagaoka, Y., Inoue, A., Maekawa, T.

PLoS ONE, 10(5) e0127481, 2015
Acetosulfation of bacterial cellulose: An unexplored promising incipient candidate for highly transparent thin film

Palaninathan, V., Chauhan, N., Poulose, A.C., Raveendran, S., Mizuki, T., Hasumura, T., Fukuda, T., Morimoto, H., Yoshida, Y., Maekawa, T. …

Materials Express, 4(5) 415-421, 2014
Activity of Lipase and Chitinase Immobilized on Superparamagnetic Particles in a Rotational Magnetic Field

Mizuki, T., Sawai, M., Nagaoka, Y., Morimoto, H., Maekawa, T.

PLoS ONE, 8(6) e66528, 2013
Synthesis of Fe-C<inf>60</inf> complex by ion irradiation

Minezaki, H., Oshima, K., Uchida, T., Mizuki, T., Racz, R., Muramatsu, M., Asaji, T., Kitagawa, A., Kato, Y., Biri, S. …

Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 310 18-22, 2013
Intracellular trafficking of superparamagnetic iron oxide nanoparticles conjugated with TAT peptide: 3-dimensional electron tomography analysis

Nair, B.G., Fukuda, T., Mizuki, T., Hanajiri, T., Maekawa, T.

Biochemical and Biophysical Research Communications, 421(4) 763-7, 2012
Activity of an enzyme immobilized on superparamagnetic particles in a rotational magnetic field

Mizuki, T., Watanabe, N., Nagaoka, Y., Fukushima, T., Morimoto, H., Usami, R., Maekawa, T.

Biochemical and Biophysical Research Communications, 393(4) 779-82, 2010

Misc.

淡水域底泥中からの新規硫酸還元磁性細菌の分離・培養

下重裕一, 小林英城, 島村繁, 水木徹, 井上明, 前川透

日本農芸化学会大会講演要旨集(Web), 2019, 2019
Synthesis and analysis of rare sugar functionalized graphene oxide

Mizuki Toru, Hirata Keisuke, Nakajima Yoshikata, Uchida Takashi, Maekawa Toru

GLYCOBIOLOGY, 27(12) 1250-1251, Dec, 2017 Peer-reviewed
Synthesis of rare sugar conjugated glycolipids by combination of chemical reaction and enzymatic reaction

Keisuke Hirata, Takashi Uchida, Yoshikata Nakajima, Seiki Iwai, Toru Mizuki

GLYCOBIOLOGY, 26(12) 1464-1464, Dec, 2016
希少糖含有糖脂質の合成と解析

平田圭亮, 内田貴司, 内田貴司, 中島義賢, 中島義賢, 水木徹, 水木徹

日本糖質学会年会要旨集, 35th 157, Aug 1, 2016
希少糖を用いた酸化グラフェンの還元および機能性の付与

小堺悠可, 平田圭亮, 内田貴司, 内田貴司, 中島義賢, 中島義賢, 水木徹, 水木徹

日本農芸化学会大会講演要旨集(Web), 2016 3K009 (WEB ONLY), Mar 5, 2016
Magnetospirillum magneticum RSS‐1株におけるFe₃O₄‐Sm₂O₃コアシェルナノ粒子の形成

下重裕一, 中島義賢, 柳澤圭一, 小林英城, 水木徹, 島村繁, 井上明, 前川透

日本農芸化学会大会講演要旨集(Web), 2016 4J011 (WEB ONLY), Mar 5, 2016
希土類元素含有磁性粒子を形成する磁性細菌の探索

下重裕一, 水木徹, 中島義賢, 小林英城, 島村繁, 井上明, 前川透

日本農芸化学会大会講演要旨集(Web), 2015 2A41P20 (WEB ONLY), Mar 5, 2015
電気泳動コールター法における精度向上

清水俊彰, 水木徹, 鵜飼智文, 東利晃, 中島義賢, 花尻達郎

応用物理学会春季学術講演会講演予稿集(CD-ROM), 62nd ROMBUNNO.14A-D6-5, Feb 26, 2015
Report on the Project Studies : Project Study of RIIT : Purification and Characterization of Halophilic Enzymes

Toru MIZUKI, Ron USAMI

(33) 38-42, 2011
X-ray crystallographic and ultracentrifugal analyses of haloarchaeal nucleoside-diphosphate kinases

Koji Nagata, Akihiro Yamamura, Takefumi Ichimura, Jun Ohtsuka, Ken-ichi Miyazono, Tsukasa Makino, Masahiko Okai, Toru Mizuki, Masahiro Kamekura, Masaru Tanokura

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 64 C340-C341, 2008

Presentations

希少糖含有糖脂質の合成と解析

平田圭亮, 内田貴司, 内田貴司, 中島義賢, 中島義賢, 水木徹, 水木徹

日本糖質学会年会要旨集, Aug 1, 2016
Magnetospirillum magneticum RSS‐1株におけるFe₃O₄‐Sm₂O₃コアシェルナノ粒子の形成

下重裕一, 中島義賢, 柳澤圭一, 小林英城, 水木徹, 島村繁, 井上明, 前川透

日本農芸化学会大会講演要旨集(Web), Mar 5, 2016
希少糖を用いた酸化グラフェンの還元および機能性の付与

小堺悠可, 平田圭亮, 内田貴司, 内田貴司, 中島義賢, 中島義賢, 水木徹, 水木徹

日本農芸化学会大会講演要旨集(Web), Mar 5, 2016
回転磁場を用いた酵素・磁性粒子複合体の活性の促進

平田圭亮, 水木徹, 立原直人, 長岡豊, 森本久雄, 前川透

日本農芸化学会大会講演要旨集(Web), Mar 5, 2015
希土類元素含有磁性粒子を形成する磁性細菌の探索

下重裕一, 水木徹, 中島義賢, 小林英城, 島村繁, 井上明, 前川透

日本農芸化学会大会講演要旨集(Web), Mar 5, 2015
電気泳動コールター法における精度向上

清水俊彰, 水木徹, 鵜飼智文, 東利晃, 中島義賢, 花尻達郎

応用物理学会春季学術講演会講演予稿集(CD-ROM), Feb 26, 2015
強磁性粒子のヒステリシス損熱を利用した酵素の活性化

鈴木政史, 安喜敦士, 水木徹, 宇佐見論, 前川透, 森本久雄

化学工学会年会研究発表講演要旨集(CD-ROM), Feb 15, 2012
強磁性粒子を利用した酵素反応促進法の開発

鈴木政史, 安喜敦士, 長岡豊, 早崎泰弘, 水木徹, 宇佐美論, 前川透, 森本久雄

化学工学会年会研究発表講演要旨集(CD-ROM), Feb 22, 2011
強磁性粒子のヒステリシス損熱を利用した特定酵素反応の促進

鈴木政史, 安喜敦士, 水木徹, 宇佐美論, 前川透, 森本久雄

応用物理学関係連合講演会講演予稿集(CD-ROM), Mar 3, 2010
高度好塩菌由来ヌクレオシドニリン酸キナーゼ2種の異なる塩濃度依存性の解明

山村昭裕, 市村武文, 亀倉正博, 水木徹, 宇佐美論, 大塚淳, 宮園健一, 岡井公彦, 永田宏次, 田之倉優

生体分子科学討論会講演要旨集, Jun 19, 2009
高度好塩菌由来ヌクレオチド二リン酸キナーゼNDK‐q,NDK‐sの異なる塩濃度依存性の構造学的解明

山村昭裕, 市村武文, 亀倉正博, 水木徹, 宇佐美論, 牧野司, 大塚淳, 宮園健一, 岡井公彦, 永田宏次, 田之倉優

日本蛋白質科学会年会プログラム・要旨集, Apr 24, 2009
高度好塩性古細菌が生産する耐塩,耐有機溶媒性マンナン分解酵素の解析

嶋根康弘, 秦田勇二, 水木徹, 峯岸宏明, 大田ゆかり, 宇佐美論, 掘越弘毅

日本農芸化学会大会講演要旨集, Mar 5, 2009
高度好塩菌Haloarcula quadrata由来ヌクレオチド二リン酸キナーゼのX線結晶構造解析

山村昭裕, 市村武文, 亀倉正博, 水木徹, 宇佐美論, 牧野司, 大塚淳, 宮園健一, 岡井公彦, 永田宏次, 田之倉優

PFシンポジウム要旨集, 2009
Haloarchaea‘Haloarcula sinallensis’とHaloarcula quadrataのNucleoside Diphosphate Kinase結晶構造解析

市村武文, 山村昭裕, 亀倉正博, 水木徹, 宇佐美論, 大塚淳, 宮園健一, 岡井公彦, 永田宏次, 田之倉優

日本Archaea研究会講演会要旨集, 2008
熱耐性,低塩濃度耐性を有する好塩性Archaea

亀倉正博, 福島忠将, 峯岸宏明, 水木徹, 越後輝敦, 長岡修平, 宇佐美論

日本Archaea研究会講演会要旨集, 2008
非塩性土壌から分離した新規好アルカリ性中度好塩性細菌の分類学的研究

越後輝敦, 峯岸宏明, 水木徹, 長岡修平, 亀倉正博, 宇佐美論

極限環境微生物学会誌, Dec, 2007
市販天日塩を用いた新奇好塩性微生物の探索

長岡修平, 峯岸宏明, 水木徹, 越後輝敦, 西澤実奈子, 亀倉正博, 宇佐美論

極限環境微生物学会誌, Dec, 2007
市販天然塩から分離された好酸性好塩性古細菌

峯岸宏明, 水木徹, 越後輝敦, 長岡修平, 亀倉正博, 宇佐美論

極限環境微生物学会誌, Dec, 2007
rpoB遺伝子とそのアミノ酸配列による好塩性古細菌の系統関係

峯岸宏明, 亀倉正博, 伊藤隆, 水木徹, 越後輝敦, 宇佐美論

極限環境微生物学会誌, Dec, 2007
rpoB遺伝子による好塩性古細菌の系統解析

峯岸宏明, 亀倉正博, 伊藤隆, 水木徹, 越後輝敦, 宇佐美論

極限環境微生物学会誌, Dec, 2007

Teaching Experience

Research Projects

細胞分析デバイスよる細胞外シグナルの計測およびその細胞の未来予測

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

中島義賢, 酒井政道, 水木徹
Development for detection of biological reactions by electrical signals to turn lab-on-a-chip into electronic devices

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Nakajima Yoshikata
Development of new nanomaterials for application to cancer treatment and medical inspection devices

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Mizuki Toru
Utilization of new materials to make practical use of electrophoresis Coulter method (ECM) as medical inspection equipment

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Hanajiri Tatsuro
Development of bio-nano analytical devices on Si-On-Quartz (SOQ) substrates

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Nakajima Yoshikata, MIZUKI Toru, UKAI Tomofumi, HANAJIRI Tatsuro
What should we do for fabrication of silicon nano structures using soft lithography techniques ?

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

HANAJIRI TATSURO, MAEKAWA Toru, NAKAJIMA Yoshikata, MIZUKI Toru, HIGASHI Toshiaki
What should we do to integrate total systems of cell sorters into one chip?

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2009 - 2011

HANAJIRI Tatsuro, YOSHIMORO Tomomi, MIZUKI Toru, KASHIWAGI Kunihiro