2013年11月
[Regulation of intracellular signal pathways via sensor proteins by oxidative stress].
Clinical calcium
- 巻
- 23
- 号
- 11
- 開始ページ
- 1613
- 終了ページ
- 9
- 記述言語
- 日本語
- 掲載種別
- 研究論文(学術雑誌)
It has been known that reactive oxygen species (ROS) control the enzymatic and transcriptional activity of proteins via direct modification of cysteine residues. Hence, oxidation of cysteine thiol could be a vital modulator of signal transduction pathways. These findings indicate that some proteins serve as the sensor proteins highly sensitive to ROS. In this review, I show the relationship between intracellular ROS sensor and the regulation of protein function via oxidation.
- リンク情報
- ID情報
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- PubMed ID : 24162601