2020年12月
Analysis of a plasmid encoding botulinum neurotoxin type G gene in Clostridium argentinense
Anaerobe
- 巻
- 66
- 号
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.anaerobe.2020.102281
Clostridium argentinense produces botulinum neurotoxin type G (BoNT/G). We sequenced and analyzed the plasmid harboring the bont/G gene, designated pCAG, in C. argentinense strain 2740. The pCAG consisted of 140,070 bp containing the bont/G gene cluster. Although this gene cluster showed high similarities in its DNA sequence and ORF arrangement to those of other bont gene clusters, the other regions of the plasmid did not. A phylogenetic study suggested that pCAG had a unique evolutionary history compared with other clostridial bont-harboring plasmids. This suggests that pCAG is possibly a novel type of plasmid expressing the bont/G gene in C. argentinense.
- リンク情報
- ID情報
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- DOI : 10.1016/j.anaerobe.2020.102281
- ISSN : 1075-9964
- eISSN : 1095-8274
- PubMed ID : 33059044
- SCOPUS ID : 85093969147