王錚 (ZHENG WANG) - マイポータル

基本情報

所属: 武田薬品工業株式会社

研究者番号: 90794313
J-GLOBAL ID: 202001016509342512
researchmap会員ID: R000012549

研究分野

学歴

2003年9月 - 2008年6月

北京協和医学院报, 清華大学医学部
1999年9月 - 2003年6月

南京大学

受賞

2019年8月

桜舞賞・研究奨励賞, 遺伝性骨疾患の新しい原因遺伝子の同定, 理化学研究所

論文

Heterozygous mutations in the straitjacket region of the latency-associated peptide domain of TGFB2 cause Camurati–Engelmann disease type II

Zheng Wang, Mitsuhiro Kometani, Leonid Zeitlin, Yael Wilnai, Akira Kinoshita, Koh-ichiro Yoshiura, Hiroko Ninomiya, Takeshi Imamura, Long Guo, Jingyi Xue …

Journal of Human Genetics 2024年7月16日査読有り
Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans.

Long Guo, Smrithi Salian, Jing-Yi Xue, Nicola Rath, Justine Rousseau, Hyunyun Kim, Sophie Ehresmann, Shahida Moosa, Norio Nakagawa, Hiroshi Kuroda …

American journal of human genetics 110(7) 1068-1085 2023年7月6日
De novo heterozygous variants in KIF5B cause kyphomelic dysplasia.

Toshiyuki Itai, Zheng Wang, Gen Nishimura, Hirofumi Ohashi, Long Guo, Yasuhiro Wakano, Takahiro Sugiura, Hiromi Hayakawa, Mayumi Okada, Takashi Saisu …

Clinical genetics 102(1) 3-11 2022年3月27日
Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling

Long Guo, Aritoshi Iida, Gandham SriLakshmi Bhavani, Kalpana Gowrishankar, Zheng Wang, Jing-yi Xue, Juan Wang, Noriko Miyake, Naomichi Matsumoto, Takanori Hasegawa …

Nature Communications 12(1) 2046-2046 2021年12月
SLC4A2 Deficiency Causes a New Type of Osteopetrosis.

Jing-Yi Xue, Giedre Grigelioniene, Zheng Wang, Gen Nishimura, Aritoshi Iida, Naomichi Matsumoto, Emma Tham, Noriko Miyake, Shiro Ikegawa, Long Guo

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 37(2) 226-235 2021年10月20日
Expanding the phenotypic spectrum of TNFRSF11A-associated dysosteosclerosis: a case with intracranial extramedullary hematopoiesis

Jing-Yi Xue, Pelin O. Simsek-Kiper, Gulen Eda Utine, Li Yan, Zheng Wang, Ekim Z. Taskiran, Beren Karaosmanoglu, Gozde Imren, Rahsan Gocmen, Gen Nishimura …

Journal of Human Genetics 66(6) 607-611 2021年6月
The third case of TNFRSF11A-associated dysosteosclerosis with a mutation producing elongating proteins

Jing-Yi Xue, Zheng Wang, Sarah F. Smithson, Christine P. Burren, Naomichi Matsumoto, Gen Nishimura, Shiro Ikegawa, Long Guo

Journal of Human Genetics 66(4) 371-377 2021年4月
Differentiation of Hypertrophic Chondrocytes from Human iPSCs for the In Vitro Modeling of Chondrodysplasias

Yann Pretemer, Shunsuke Kawai, Sanae Nagata, Megumi Nishio, Makoto Watanabe, Sakura Tamaki, Cantas Alev, Yoshihiro Yamanaka, Jing-Yi Xue, Zheng Wang …

Stem Cell Reports 16(3) 610-625 2021年3月
Regulatory Role of the RNA N6-Methyladenosine Modification in Immunoregulatory Cells and Immune-Related Bone Homeostasis Associated With Rheumatoid Arthritis

Danping Fan, Ya Xia, Cheng Lu, Qinbin Ye, Xiaoyu Xi, Qiong Wang, Zheng Wang, Chengyuan Wang, Cheng Xiao

Frontiers in Cell and Developmental Biology 8 2021年1月21日
Identification of novel FBN1 variations implicated in congenital scoliosis

Mao Lin, Sen Zhao, Gang Liu, Yingzhao Huang, Chenxi Yu, Yanxue Zhao, Lianlei Wang, Yuanqiang Zhang, Zihui Yan, Shengru Wang …

Journal of Human Genetics 65(3) 221-230 2020年3月
TNFRSF11A ‐Associated Dysosteosclerosis: A Report of the Second Case and Characterization of the Phenotypic Spectrum

Jing‐yi Xue, Zheng Wang, Satoshi Shinagawa, Hirofumi Ohashi, Nao Otomo, Nursel H Elcioglu, Tomoki Nakashima, Gen Nishimura, Shiro Ikegawa, Long Guo

Journal of Bone and Mineral Research 34(10) 1873-1879 2019年10月
Bi-allelic CSF1R Mutations Cause Skeletal Dysplasia of Dysosteosclerosis-Pyle Disease Spectrum and Degenerative Encephalopathy with Brain Malformation

Long Guo, Débora Romeo Bertola, Asako Takanohashi, Asuka Saito, Yuko Segawa, Takanori Yokota, Satoru Ishibashi, Yoichiro Nishida, Guilherme Lopes Yamamoto, José Francisco da Silva Franco …

The American Journal of Human Genetics 104(5) 925-935 2019年5月
Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia

Hae Ryung Chang, Sung Yoon Cho, Jae Hoon Lee, Eunkyung Lee, Jieun Seo, Hye Ran Lee, Denise P. Cavalcanti, Outi Mäkitie, Helena Valta, Katta M. Girisha …

The American Journal of Human Genetics 104(3) 439-453 2019年3月
Clinical characteristics and spectrum of NF1 mutations in 12 unrelated Chinese families with neurofibromatosis type 1

Bin Mao, Siyu Chen, Xin Chen, Xiumei Yu, Xiaojia Zhai, Tao Yang, Lulu Li, Zheng Wang, Xiuli Zhao, Xue Zhang

BMC Medical Genetics 19(1) 2018年12月
Further expansion of the mutational spectrum of spondylo-meta-epiphyseal dysplasia with abnormal calcification

Gizem Ürel-Demir, Pelin Ozlem Simsek-Kiper, Özlem Akgün-Doğan, Rahşan Göçmen, Zheng Wang, Naomichi Matsumoto, Noriko Miyake, Gülen Eda Utine, Gen Nishimura, Shiro Ikegawa …

Journal of Human Genetics 63(9) 1003-1007 2018年9月
Dysosteosclerosis is also caused by TNFRSF11A mutation

Long Guo, Nursel H. Elcioglu, Ozge K. Karalar, Mert O. Topkar, Zheng Wang, Yuma Sakamoto, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa

Journal of Human Genetics 63(6) 769-774 2018年6月
Novel KIAA0753 mutations extend the phenotype of skeletal ciliopathies

A. Hammarsjö, Z. Wang, R. Vaz, F. Taylan, M. Sedghi, K. M. Girisha, D. Chitayat, K. Neethukrishna, P. Shannon, R. Godoy …

Scientific Reports 7(1) 2017年12月筆頭著者
Novel and recurrent COL11A1 and COL2A1 mutations in the Marshall–Stickler syndrome spectrum

Long Guo, Nursel H Elcioglu, Zheng Wang, Yasemin K Demirkol, Pinar Isguven, Naomichi Matsumoto, Gen Nishimura, Noriko Miyake, Shiro Ikegawa

Human Genome Variation 4(1) 17040-17040 2017年12月
Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia

Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura …

Journal of Human Genetics 62(8) 797-801 2017年8月
Axial spondylometaphyseal dysplasia is also caused by NEK1 mutations

Zheng Wang, Eva Horemuzova, Aritoshi Iida, Long Guo, Ying Liu, Naomichi Matsumoto, Gen Nishimura, Ann Nordgren, Noriko Miyake, Emma Tham …

Journal of Human Genetics 62(4) 503-506 2017年4月筆頭著者