佐伯宣久 (Norihisa Saeki) - マイポータル

基本情報

所属: 沖縄県立看護大学・大学院人体構造機能学教授

学位: 博士（医学）(琉球大学)

J-GLOBAL ID: 201901021434340996
researchmap会員ID: B000366045

経歴、学歴、研究業績などの詳細は沖縄県立看護大学ホームページの教員情報をご覧ください（https://www.okinawa-nurs.ac.jp/daigaku/kyouin/detail/?user=norihisa-saeki）

研究キーワード

研究分野

経歴

2016年 - 現在

沖縄県立看護大学・大学院, 教授
2010年 - 2015年

国立がん研究センター研究所, 遺伝医学研究分野, 主任研究員
2005年 - 2009年

国立がんセンター研究所, 研究員

学歴

- 2000年

琉球大学大学院, 医学研究科形, 態機能系専攻
- 1992年

琉球大学, 医学部, 医学科

論文

Indirect Down-regulation of Tumor-suppressive let-7 Family MicroRNAs by LMO1 in Neuroblastoma.

Saeki N, Saito A, Sugaya Y, Amemiya M, Sasaki H

Cancer genomics & proteomics 15(5) 413-420 2018年9月査読有り
Chromatin immunoprecipitation and DNA sequencing identified a LIMS1/ILK pathway regulated by LMO1 in neuroblastoma

Norihisa Saeki, Akira Saito, Yuki Sugaya, Mitsuhiro Amemiya, Hiroe Ono, Rie Komatsuzaki, Kazuyoshi Yanagihara, Hiroki Sasaki

Cancer Genomics and Proteomics 15(3) 165-174 2018年5月1日査読有り
Prostate stem cell antigen is expressed in normal and malignant human brain tissues

Hiroe Ono, Hiromi Sakamoto, Teruhiko Yoshida, Norihisa Saeki

Oncology Letters 15(3) 3081-3084 2018年3月1日査読有り
rs2294008T, a risk allele for gastric and gallbladder cancers, suppresses the PSCA promoter by recruiting the transcription factor YY1

Norihisa Saeki, Hiroe Ono, Kazuyoshi Yanagihara, Kazuhiko Aoyagi, Hiroki Sasaki, Hiromi Sakamoto, Teruhiko Yoshida

GENES TO CELLS 20(5) 382-391 2015年5月査読有り
Down-regulation of Immune-related Genes by PSCA in Gallbladder Cancer Cells Implanted into Mice

Norihisa Saeki, Hiroe Ono, Hiromi Sakamoto, Teruhiko Yoshida

ANTICANCER RESEARCH 35(5) 2619-2625 2015年5月査読有り
A GSDMB enhancer-driven HSV thymidine kinase-expressing vector for controlling occult peritoneal dissemination of gastric cancer cells

Norihisa Saeki, Rie Komatsuzaki, Fumiko Chiwaki, Kazuyoshi Yanagihara, Hiroki Sasaki

BMC CANCER 15 439 2015年5月査読有り
Mucin 1 Gene (MUC1) and Gastric-Cancer Susceptibility

Norihisa Saeki, Hiromi Sakamoto, Teruhiko Yoshida

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15(5) 7958-7973 2014年5月査読有り
Genetic factors related to gastric cancer susceptibility identified using a genome-wide association study

Norihisa Saeki, Hiroe Ono, Hiromi Sakamoto, Teruhiko Yoshida

CANCER SCIENCE 104(1) 1-8 2013年1月査読有り
Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells

Hiroe Ono, Dai Chihara, Fumiko Chiwaki, Kazuyoshi Yanagihara, Hiroki Sasaki, Hiromi Sakamoto, Hideo Tanaka, Teruhiko Yoshida, Norihisa Saeki, Keitaro Matsuo

Journal of Carcinogenesis 12 4 2013年1月1日査読有り
Prostate stem cell antigen gene is expressed in islets of pancreas.

Ono H, Yanagihara K, Sakamoto H, Yoshida T, Saeki N

Anatomy & cell biology 45(3) 149-154 2012年9月査読有り
Polycomb and DNA methyltransferase complexes participate in global and focal epigenetic alterations in cancer cells

Norihisa Saeki, Hiroki Sasaki

EPIGENOMICS 4(2) 133-134 2012年4月査読有り
Focal DNA methylation of ten cancer-associated genes in gastric cancer.

Saeki N, Sasaki H

Epigenomics 4(2) 134 2012年4月査読有り
Prostate Stem Cell Antigen, a Presumable Organ-Dependent Tumor Suppressor Gene, is Down-Regulated in Gallbladder Carcinogenesis

Hiroe Ono, Nobuyoshi Hiraoka, Yeon-Su Lee, Sang Myung Woo, Woo Jin Lee, Il Ju Choi, Akira Saito, Kazuyoshi Yanagihara, Yae Kanai, Sumiko Ohnami …

GENES CHROMOSOMES & CANCER 51(1) 30-41 2012年1月査読有り
A Functional Single Nucleotide Polymorphism in Mucin 1, at Chromosome 1q22, Determines Susceptibility to Diffuse-Type Gastric Cancer

Norihisa Saeki, Akira Saito, Il Ju Choi, Keitaro Matsuo, Sumiko Ohnami, Hirohiko Totsuka, Suenori Chiku, Aya Kuchiba, Yeon-Su Lee, Kyong-Ah Yoon …

GASTROENTEROLOGY 140(3) 892-902 2011年3月査読有り
Integrative genomics identifies LMO1 as a neuroblastoma oncogene

Kai Wang, Sharon J. Diskin, Haitao Zhang, Edward F. Attiyeh, Cynthia Winter, Cuiping Hou, Robert W. Schnepp, Maura Diamond, Kristopher Bosse, Patrick A. Mayes …

NATURE 469(7329) 216-220 2011年1月査読有り
Prostate Stem Cell Antigen: A Jekyll and Hyde Molecule?

Norihisa Saeki, Jian Gu, Teruhiko Yoshida, Xifeng Wu

CLINICAL CANCER RESEARCH 16(14) 3533-3538 2010年7月査読有り
Genome-wide germline analyses on cancer susceptibility and GeMDBJ database: Gastric cancer as an example

Teruhiko Yoshida, Hiroe Ono, Aya Kuchiba, Norihisa Saeki, Hiromi Sakamoto

Cancer Science 101(7) 1582-1589 2010年7月査読有り
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer

Xifeng Wu, Yuanqing Ye, Lambertus A. Kiemeney, Patrick Sulem, Thorunn Rafnar, Giuseppe Matullo, Daniela Seminara, Teruhiko Yoshida, Norihisa Saeki, Angeline S. Andrew …

NATURE GENETICS 41(9) 991-U54 2009年9月査読有り
[Genome-wide association study of gastric cancer and GeMDBJ database].

Saeki N, Sakamoto H, Yoshida T

Nihon rinsho. Japanese journal of clinical medicine 67(6) 1227-1232 2009年6月査読有り
Distinctive Expression and Function of Four GSDM Family Genes (GSDMA-D) in Normal and Malignant Upper Gastrointestinal Epithelium

Norihisa Saeki, Takebumi Usui, Kazuhiko Aoyagi, Dal Ho Kim, Megumi Sato, Tomoko Mabuchi, Kazuyoshi Yanagihara, Kenji Ogawa, Hiromi Sakamoto, Teruhiko Yoshida …

GENES CHROMOSOMES & CANCER 48(3) 261-271 2009年3月査読有り

もっとみる

書籍等出版物

Prostate stem cell antigen and pancreatic cancer. In: Endocrine disease.

Saeki N, Ono H

iConcept Press Ltd 2014年
Gasdermin Superfamily: a novel gene family functioning in epithelial cells. In: Endothelium and Epithelium: composition, functions and pathology

Saeki N, Sasaki H

Nova Science Publishers, Inc. 2012年