2011年4月
Characteristic alteration in the second derivative of photoplethysmogram in children
PEDIATRICS INTERNATIONAL
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- 巻
- 53
- 号
- 2
- 開始ページ
- 154
- 終了ページ
- 158
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1111/j.1442-200X.2010.03235.x
- 出版者・発行元
- WILEY-BLACKWELL
Background:
The second derivative of the photoplethysmogram (SDPTG) has been verified as a useful method for analyzing pulse wave form in adults; however, there have been few studies on the SDPTG in children.
Methods:
We examined age-related alteration of SDPTG (study 1) and the SDPTG response to a vasodilator (study 2). The subjects in study 1 were 36 healthy children aged 0.9-16.0 years. The subjects in study 2 were 13 children aged 5.4-18.9 years with a history of Kawasaki disease. Subjects received an i.v. infusion of 0.568 mg/kg dipyridamole. We assessed the SDPTG by d/a ratio, b/a ratio and aging index (AGI).
Results:
The d/a ratio increased with advance of age (r = 0.636, P < 0.001), and the b/a ratio and AGI decreased with advance of age (r = -0.343, P < 0.05 and r = -0.678, P < 0.001, respectively). The d/a ratio and AGI were correlated with height (r = 0.523, P < 0.01 and r = -0.623, P < 0.001, respectively), but the b/a ratio was not significantly correlated with height. In study 2, the d/a ratio increased significantly (P < 0.05), but the b/a ratio and AGI did not alter.
Conclusions:
The SDPTG indices in children show characteristic alterations with advance of age and react to a vasodilator.
The second derivative of the photoplethysmogram (SDPTG) has been verified as a useful method for analyzing pulse wave form in adults; however, there have been few studies on the SDPTG in children.
Methods:
We examined age-related alteration of SDPTG (study 1) and the SDPTG response to a vasodilator (study 2). The subjects in study 1 were 36 healthy children aged 0.9-16.0 years. The subjects in study 2 were 13 children aged 5.4-18.9 years with a history of Kawasaki disease. Subjects received an i.v. infusion of 0.568 mg/kg dipyridamole. We assessed the SDPTG by d/a ratio, b/a ratio and aging index (AGI).
Results:
The d/a ratio increased with advance of age (r = 0.636, P < 0.001), and the b/a ratio and AGI decreased with advance of age (r = -0.343, P < 0.05 and r = -0.678, P < 0.001, respectively). The d/a ratio and AGI were correlated with height (r = 0.523, P < 0.01 and r = -0.623, P < 0.001, respectively), but the b/a ratio was not significantly correlated with height. In study 2, the d/a ratio increased significantly (P < 0.05), but the b/a ratio and AGI did not alter.
Conclusions:
The SDPTG indices in children show characteristic alterations with advance of age and react to a vasodilator.
- リンク情報
- ID情報
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- DOI : 10.1111/j.1442-200X.2010.03235.x
- ISSN : 1328-8067
- PubMed ID : 20738802
- Web of Science ID : WOS:000289683100004