安保博仁 (Hirohito Abo) - マイポータル

基本情報

所属: ジョージア州立大学

研究者番号: 80868050
ORCID iD: https://orcid.org/0000-0002-3066-8584
J-GLOBAL ID: 202201017872607804
researchmap会員ID: R000032689

論文

Wheat fiber mitigates colitis via non-SCFA microbial metabolite-trained intestinal macrophages

Seong-eun G. Kim, Rachael Ott, Alexis Bretin, Hirohito Abo, Yanling Wang, Yadong Wang, Shawn Winer, Daniel A. Winer, Lavanya Reddivari, Stacey L. Heaver …

Science Advances 12(13) 2026年3月27日査読有り
Antibody therapeutics with high affinity for FcγRs exacerbate anaphylaxis via FcγR-mediated capture by tumor-associated myeloid cells

Ruiheng Tang, Aibai Aizemaiti, Yuta Tamemoto, Riho Kume, Kazuto Yasuda, Kenta Sato, Hirohito Abo, Kazuto Tsuji, Kyohei Higashi, Masato Kiyoshi …

Journal for ImmunoTherapy of Cancer 14(3) e013316-e013316 2026年3月4日査読有り
Segmented filamentous bacteria reprogramming of alveolar macrophages limits postinfluenza bacterial pneumonia

Vu L. Ngo, Carolin M. Lieber, Hirohito Abo, Michal Kuczma, Jun Zou, Richard K. Plemper, Andrew T. Gewirtz

Science Immunology 11(115) 2026年1月2日査読有り
Wheat fiber-induced peripheral regulatory T-cells suppress development of colitis

Seong-eun G. Kim, Hirohito Abo, Yanling Wang, Shawn Winer, Daniel A. Winer, Michael Pellizzon, Vu L. Ngo, Andrew T. Gewirtz

Mucosal Immunology 2025年12月査読有り
Flagellin in the human gut microbiome is a diet-adjustable adjuvant for vaccination

Kelsey E. Huus, Yi Han Tan, Hirohito Abo, Ronald Keller, Ezgi Atay, Dai Long Vu, Silke Dauser, Alina Prokipchuk, Alexander V. Tyakht, Nicholas Youngblut …

2025年2月24日
Reprogramming of alveolar macrophages by intestinal segmented filamentous bacteria protects mice from lethal bacterial pneumoniae following influenza infection

Vu L. Ngo, Carolin M. Lieber, Hirohito Abo, Michal Kuczma, Richard K. Plemper, Andrew T. Gewirtz

2025年1月26日
Wheat Fiber Suppresses Development of Colitis via Microbiota-Mediated Fermentation-Independent Metabolites that Reprogram Intestinal Macrophages

Seong-eun G. Kim, Rachael Ott, Alexis Bretin, Hirohito Abo, Yanling Wang, Yadong Wang, Shawn Winer, Daniel A. Winer, Levanya Reddivari, Stacey Heaver …

2025年
Sialyl Lewis X Defines an Activated and Functional Regulatory T Cell Subpopulation in Mice.

Kanae Ohishi, Asaki Ishikura, Shogo Nishida, Hirohito Abo, Hiroko Nakatsukasa, Hiroto Kawashima

Journal of immunology (Baltimore, Md. : 1950) 2024年4月19日査読有り
Prevention of experimental autoimmune encephalomyelitis by targeting 6-sulfo sialyl Lewis X glycans involved in lymphocyte homing

Qianqian Liu, Wei Xiong, Sachiyo Obara, Hirohito Abo, Hiroko Nakatsukasa, Hiroto Kawashima

International Immunology 2024年2月22日査読有り
Editorial: Impact of gut ecosystem in health and diseases: microbiome, mucosal barrier and cytokine milieu

Akihito Harusato, Hirohito Abo, Yoshito Itoh, Timothy L. Denning

Frontiers in Microbiology 14 2024年1月5日査読有り
Protocol for acquiring samples to assess the impact of microplastics on immune microenvironments in the mouse intestine

Akihito Harusato, Wooseok Seo, Hirohito Abo, Yoshitaka Nakanishi, Hiroyoshi Nishikawa, Yoshito Itoh

STAR Protocols 4(4) 102648-102648 2023年12月査読有り
Dual function of angiogenin-4 inducing intestinal stem cells and apoptosis

Hirohito Abo, Mst. Farzana Sultana, Hiroto Kawashima

Frontiers in Cell and Developmental Biology 11 2023年11月2日査読有り筆頭著者責任著者
Significance of Sulfated Glycans on Mucins in the Gut

Hirohito Abo, Hiroto Kawashima

Trends in Glycoscience and Glycotechnology 35(207) E73-E77 2023年9月25日査読有り筆頭著者
N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota

Hirohito Abo, Aoi Muraki, Akihito Harusato, Tetsuya Imura, Maki Suzuki, Kohta Takahashi, Timothy L. Denning, Hiroto Kawashima

JCI Insight 2023年7月18日査読有り筆頭著者責任著者
Therapeutic Effects of an Anti-Sialyl Lewis x Antibody in a Murine Model of Acute Lung Injury

Wenxin Liu, Wei Xiong, Wei Liu, Zihong Wei, Hirohito Abo, Hiroto Kawashima

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 2023年4月13日査読有り
Impact of particulate microplastics generated from polyethylene terephthalate on gut pathology and immune microenvironments

Akihito Harusato, Wooseok Seo, Hirohito Abo, Yoshitaka Nakanishi, Hiroyoshi Nishikawa, Yoshito Itoh

iScience 26(4) 106474-106474 2023年4月査読有り
Tumor-associated neutrophils and macrophages exacerbate antidrug IgG-mediated anaphylactic reaction against an immune checkpoint inhibitor

Takahiro Arai, Tomomi Kokubo, Ruiheng Tang, Hirohito Abo, Ayu Terui, Jotaro Hirakawa, Hidetaka Akita, Hiroto Kawashima, Akihiro Hisaka, Hiroto Hatakeyama

Journal for ImmunoTherapy of Cancer 10(12) e005657-e005657 2022年12月査読有り
Human and mouse angiogenins: Emerging insights and potential opportunities

Mst. Farzana Sultana, Hirohito Abo, Hiroto Kawashima

Frontiers in Microbiology 13 2022年11月17日査読有り責任著者
Identification of Crucial Amino Acid Residues for Antimicrobial Activity of Angiogenin 4 and Its Modulation of Gut Microbiota in Mice.

Mst Farzana Sultana, Maki Suzuki, Fumiya Yamasaki, Wataru Kubota, Kohta Takahashi, Hirohito Abo, Hiroto Kawashima

Frontiers in microbiology 13 900948-900948 2022年査読有り
Disaccharide-tag for highly sensitive identification of O-GlcNAc-modified proteins in mammalian cells.

Hirohito Abo, Masahiko Kume, Federico Pecori, Taichi Miura, Naoki Matsumoto, Shoko Nishihara, Kazuo Yamamoto

PloS one 17(5) e0267804 2022年査読有り筆頭著者

もっとみる

共同研究・競争的資金等の研究課題

ムチン糖鎖硫酸化修飾と腸内細菌を基軸とした代謝関連疾患の基盤的研究

日本学術振興会科学研究費助成事業若手研究 2023年4月 - 2024年3月

安保博仁
炎症性腸疾患の病態形成におけるムチン糖鎖硫酸化の意義

日本学術振興会科学研究費助成事業若手研究 2020年4月 - 2023年3月

安保博仁
糖鎖を標的とする新規多発性硬化症治療抗体の開発に向けた基盤研究

日本学術振興会科学研究費助成事業基盤研究(B) 2020年4月 - 2023年3月

川島博人, 小林基弘, 安保博仁

安保博仁

基本情報

論文

共同研究・競争的資金等の研究課題

メニュー

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