論文

査読有り
2015年3月

[CD20-positive plasma cell myeloma with lymphoplasmacytoid appearance mimicking low-grade B-cell lymphoma].

[Rinsho ketsueki] The Japanese journal of clinical hematology
  • Shojiro Haji
  • ,
  • Yasunobu Abe
  • ,
  • Mariko Tsuda
  • ,
  • Kosuke Toyoda
  • ,
  • Ilseung Choi
  • ,
  • Youko Suehiro
  • ,
  • Motoaki Shiratsuchi
  • ,
  • Junichi Kiyasu
  • ,
  • Naokuni Uike

56
3
開始ページ
335
終了ページ
8
記述言語
日本語
掲載種別
研究論文(学術雑誌)
DOI
10.11406/rinketsu.56.335

CD 20 positive myeloma with small lymphoplasmacytoid morphology is difficult to differentiate from mature B-cell lymphoma. A 71-year-old male was referred to our hospital because of osteolytic vertebral fractures and anemia. Urine was positive for Bence Jones protein, κ type. Bone marrow consisted of approximately 30% small lymphoplasmacytoid cells with scant cytoplasm, and these cells were positive for CD20, CD23 and CD138. FISH analysis revealed t(11;14)(CCND1/IGH). Myeloma with t(11;14) is closely associated with small lymphoplasmacytoid appearance and CD20 and CD23 expressions. The patient was diagnosed as having myeloma based on clinical and cytogenetic findings, and achieved VGPR (very good partial response) after treatment with lenalidomide.

リンク情報
DOI
https://doi.org/10.11406/rinketsu.56.335
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25876789
ID情報
  • DOI : 10.11406/rinketsu.56.335
  • PubMed ID : 25876789

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