Hiroshi Akashi

J-GLOBAL         Last updated: Jan 4, 2019 at 13:54
 
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Name
Hiroshi Akashi
URL
http://www.nig.ac.jp/labs/EvoGen/
Affiliation
National Institute of Genetics
Section
Department of Population Genetics
Job title
Professor of Evolutionary Genetics
Degree
PhD(University of Chicago, USA), BA(Harvard University, USA)

Research Areas

 
 

Academic & Professional Experience

 
Jan 2009
 - 
Today
Professor of Evolutionary Genetics, Department of Population Genetics, National Institute of Genetics
 
Jul 2006
 - 
Dec 2008
Associate Professor, Department of Biology, Penn State University
 
Aug 2000
 - 
Jun 2006
Assistant Professor, Department of Biology, Penn State University
 
Aug 1998
 - 
Jul 2000
Assistant Professor, Department of Ecology and Evolutionary Biology, University of Kansas
 
Sep 1996
 - 
Aug 1998
Visiting Scholar, Section of Evolution and Ecology, University of California, Davis
 

Education

 
Jan 1996
 - 
Jan 1991
MS/PhD, Ecology and Evolution, University of Chicago
 
Aug 1985
 - 
Jan 1990
Biology, Harvard College
 

Committee Memberships

 
Jan 2004
 - 
Today
Faculty of 1000 Biology  Contributing Faculty Member for
 
 
 - 
Today
BMC Genomics  Associate Editor for
 

Awards & Honors

 
Jun 1998
Young Investigator Award, American Society of Naturalists
 
Sep 1996
Young Investigator Award in Molecular Studies of Evolution, Alfred P. Sloan Foundation
 
Jan 1996
Departmental Award for Outstanding Performance in the General Field of Ecology and Evolution, University of Chicago
 
Jan 1990
magna cum laude with highest honors in the Department of Biology, Harvard College
 

Published Papers

 
Matsumoto T, John A, Baeza-Centurion P, Li B, Akashi H
Molecular biology and evolution   33(6) 1580-1589   Jun 2016   [Refereed]
Matsumoto T, Akashi H, Yang Z
Genetics   200(3) 873-890   Jul 2015   [Refereed]
Mallik S, Akashi H, Kundu S
Nucleic acids research   43(11) 5352-5363   Jun 2015   [Refereed]
Akashi H, Osada N, Ohta T
Genetics   192 15-31   Sep 2012   [Refereed]
Osada N, Akashi H
Molecular biology and evolution   29 337-346   Jan 2012   [Refereed]
Raiford DW, Heizer EM Jr, Miller RV, Akashi H, Raymer ML, Krane DE
Journal of molecular evolution   67 621-630   Dec 2008   [Refereed]
Drosophila 12 Genomes Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B, Aguade M, Akashi H, Anderson WW, Aquadro CF, Ardell DH, Arguello R, Artieri CG, Barbash DA, Barker D, Barsanti P, Batterham P, Batzoglou S, Begun D, Bhutkar A, Blanco E, Bosak SA, Bradley RK, Brand AD, Brent MR, Brooks AN, Brown RH, Butlin RK, Caggese C, Calvi BR, Bernardo de Carvalho A, Caspi A, Castrezana S, Celniker SE, Chang JL, Chapple C, Chatterji S, Chinwalla A, Civetta A, Clifton SW, Comeron JM, Costello JC, Coyne JA, Daub J, David RG, Delcher AL, Delehaunty K, Do CB, Ebling H, Edwards K, Eickbush T, Evans JD, Filipski A, Findeiss S, Freyhult E, Fulton L, Fulton R, Garcia AC, Gardiner A, Garfield DA, Garvin BE, Gibson G, Gilbert D, Gnerre S, Godfrey J, Good R, Gotea V, Gravely B, Greenberg AJ, Griffiths-Jones S, Gross S, Guigo R, Gustafson EA, Haerty W, Hahn MW, Halligan DL, Halpern AL, Halter GM, Han MV, Heger A, Hillier L, Hinrichs AS, Holmes I, Hoskins RA, Hubisz MJ, Hultmark D, Huntley MA, Jaffe DB, Jagadeeshan S, Jeck WR, Johnson J, Jones CD, Jordan WC, Karpen GH, Kataoka E, Keightley PD, Kheradpour P, Kirkness EF, Koerich LB, Kristiansen K, Kudrna D, Kulathinal RJ, Kumar S, Kwok R, Lander E, Langley CH, Lapoint R, Lazzaro BP, Lee SJ, Levesque L, Li R, Lin CF, Lin MF, Lindblad-Toh K, Llopart A, Long M, Low L, Lozovsky E, Lu J, Luo M, Machado CA, Makalowski W, Marzo M, Matsuda M, Matzkin L, McAllister B, McBride CS, McKernan B, McKernan K, Mendez-Lago M, Minx P, Mollenhauer MU, Montooth K, Mount SM, Mu X, Myers E, Negre B, Newfeld S, Nielsen R, Noor MA, O'Grady P, Pachter L, Papaceit M, Parisi MJ, Parisi M, Parts L, Pedersen JS, Pesole G, Phillippy AM, Ponting CP, Pop M, Porcelli D, Powell JR, Prohaska S, Pruitt K, Puig M, Quesneville H, Ram KR, Rand D, Rasmussen MD, Reed LK, Reenan R, Reily A, Remington KA, Rieger TT, Ritchie MG, Robin C, Rogers YH, Rohde C, Rozas J, Rubenfield MJ, Ruiz A, Russo S, Salzberg SL, Sanchez-Gracia A, Saranga DJ, Sato H, Schaeffer SW, Schatz MC, Schlenke T, Schwartz R, Segarra C, Singh RS, Sirot L, Sirota M, Sisneros NB, Smith CD, Smith TF, Spieth J, Stage DE, Stark A, Stephan W, Strausberg RL, Strempel S, Sturgill D, Sutton G, Sutton GG, Tao W, Teichmann S, Tobari YN, Tomimura Y, Tsolas JM, Valente VL, Venter E, Venter JC, Vicario S, Vieira FG, Vilella AJ, Villasante A, Walenz B, Wang J, Wasserman M, Watts T, Wilson D, Wilson RK, Wing RA, Wolfner MF, Wong A, Wong GK, Wu CI, Wu G, Yamamoto D, Yang HP, Yang SP, Yorke JA, Yoshida K, Zdobnov E, Zhang P, Zhang Y, Zimin AV, Baldwin J, Abdouelleil A, Abdulkadir J, Abebe A, Abera B, Abreu J, Acer SC, Aftuck L, Alexander A, An P, Anderson E, Anderson S, Arachi H, Azer M, Bachantsang P, Barry A, Bayul T, Berlin A, Bessette D, Bloom T, Blye J, Boguslavskiy L, Bonnet C, Boukhgalter B, Bourzgui I, Brown A, Cahill P, Channer S, Cheshatsang Y, Chuda L, Citroen M, Collymore A, Cooke P, Costello M, D'Aco K, Daza R, De Haan G, DeGray S, DeMaso C, Dhargay N, Dooley K, Dooley E, Doricent M, Dorje P, Dorjee K, Dupes A, Elong R, Falk J, Farina A, Faro S, Ferguson D, Fisher S, Foley CD, Franke A, Friedrich D, Gadbois L, Gearin G, Gearin CR, Giannoukos G, Goode T, Graham J, Grandbois E, Grewal S, Gyaltsen K, Hafez N, Hagos B, Hall J, Henson C, Hollinger A, Honan T, Huard MD, Hughes L, Hurhula B, Husby ME, Kamat A, Kanga B, Kashin S, Khazanovich D, Kisner P, Lance K, Lara M, Lee W, Lennon N, Letendre F, LeVine R, Lipovsky A, Liu X, Liu J, Liu S, Lokyitsang T, Lokyitsang Y, Lubonja R, Lui A, MacDonald P, Magnisalis V, Maru K, Matthews C, McCusker W, McDonough S, Mehta T, Meldrim J, Meneus L, Mihai O, Mihalev A, Mihova T, Mittelman R, Mlenga V, Montmayeur A, Mulrain L, Navidi A, Naylor J, Negash T, Nguyen T, Nguyen N, Nicol R, Norbu C, Norbu N, Novod N, O'Neill B, Osman S, Markiewicz E, Oyono OL, Patti C, Phunkhang P, Pierre F, Priest M, Raghuraman S, Rege F, Reyes R, Rise C, Rogov P, Ross K, Ryan E, Settipalli S, Shea T, Sherpa N, Shi L, Shih D, Sparrow T, Spaulding J, Stalker J, Stange-Thomann N, Stavropoulos S, Stone C, Strader C, Tesfaye S, Thomson T, Thoulutsang Y, Thoulutsang D, Topham K, Topping I, Tsamla T, Vassiliev H, Vo A, Wangchuk T, Wangdi T, Weiand M, Wilkinson J, Wilson A, Yadav S, Young G, Yu Q, Zembek L, Zhong D, Zimmer A, Zwirko Z, Jaffe DB, Alvarez P, Brockman W, Butler J, Chin C, Gnerre S, Grabherr M, Kleber M, Mauceli E, MacCallum I
Nature   450 203-218   Nov 2007   [Refereed]
Ko WY, Piao S, Akashi H
Genetics   174 349-362   Sep 2006   [Refereed]
Akashi H, Ko WY, Piao S, John A, Goel P, Lin CF, Vitins AP
Genetics   172 1711-1726   Mar 2006   [Refereed]
Ko WY, David RM, Akashi H
Journal of molecular evolution   57 562-573   Nov 2003   [Refereed]
Translational selection and yeast proteome evolution.
Akashi H
Genetics   164 1291-1303   Aug 2003   [Refereed]
Akashi H, Gojobori T
Proceedings of the National Academy of Sciences of the United States of America   99 3695-3700   Mar 2002   [Refereed]
Akashi H
Current opinion in genetics & development   11 660-666   Dec 2001   [Refereed]
Inferring the fitness effects of DNA mutations from polymorphism and divergence data: statistical power to detect directional selection under stationarity and free recombination.
Akashi H
Genetics   151 221-238   Jan 1999   [Refereed]
Akashi H, Eyre-Walker A
Current opinion in genetics & development   8 688-693   Dec 1998   [Refereed]
Mutation pressure, natural selection, and the evolution of base composition in Drosophila.
Akashi H, Kliman RM, Eyre-Walker A
Genetica   102-103 49-60   1998   [Refereed]
Akashi H
Gene   205 269-278   Dec 1997   [Refereed]
Distinguishing the effects of mutational biases and natural selection on DNA sequence variation.
Akashi H
Genetics   147 1989-1991   Dec 1997   [Refereed]
Natural selection and the frequency distributions of "silent" DNA polymorphism in Drosophila.
Akashi H, Schaeffer SW
Genetics   146 295-307   May 1997   [Refereed]
Molecular evolution between Drosophila melanogaster and D. simulans: reduced codon bias, faster rates of amino acid substitution, and larger proteins in D. melanogaster.
Akashi H
Genetics   144 1297-1307   Nov 1996   [Refereed]
Dorit RL, Akashi H, Gilbert W
Science (New York, N.Y.)   272 1361-1362   May 1996   [Refereed]
Dorit RL, Akashi H, Gilbert W
Science (New York, N.Y.)   268 1183-1185   May 1995   [Refereed]
Inferring weak selection from patterns of polymorphism and divergence at "silent" sites in Drosophila DNA.
Akashi H
Genetics   139 1067-1076   Feb 1995   [Refereed]
Synonymous codon usage in Drosophila melanogaster: natural selection and translational accuracy.
Akashi H
Genetics   136 927-935   Mar 1994   [Refereed]

Books etc

 
Urban Resilience A Transformative Approach Y. Yamagata & H. Maruyama (Eds.), Chapter 10 Disease Outbreaks: Critical Biological Factors
Kent Kawashima, Tomotaka Matsumoto and Hiroshi Akashi (Part:Joint Work, Chapter 10 Disease Outbreaks: Critical Biological Factors)
Springer   Oct 2016   
Encyclopedia of Evolutionary Biology 1st Edition
Editor-in-Chiefs: Richard Kliman, Section Editor for "Molecular and Genome Evolution", Hiroshi Akashi (Part:Joint Editor)
Academic Press   May 2016   ISBN:012800049X

Conference Activities & Talks

 
Population genomics of weak selection and lineage specific evolution in Drosophila
Hiroshi Akashi
International Symposium on Evolutionary Genomics and Bioinformatics, National Taiwan University, Taiwan   22 Oct 2018   
A new approach to estimate site frequency spectrum: application to infer evolutionary forces on base composition in Drosophila genomes [Invited]
Tomotaka Matsumoto, Hiroshi Akashi
Symposium on Evolutionary Genetics and Omics, Mishima, Japan   14 Jul 2018   
Approximate method for inferring site frequency spectra of polymorphism in recombining regions
Tomotaka Matsumoto, Hiroshi Akashi
Society for Molecular Biology and Evolution (SMBE) 2018, Yokohama, Japan   9 Jul 2018   
’Hitchhiking’ and adaptive protein evolution: Why do fast-evolving proteins show reduced codon usage bias in Drosophila
Hiroshi Akashi
International Symposium of Evolution of Genes and Genomes, Chengdu, China   23 Apr 2018   
’Hitchhiking’ and adaptive protein evolution: Why do fast-evolving proteins show reduced codon usage bias in Drosophila [Invited]
Hiroshi Akashi
The 1st AsiaEvo Conference, Shenzhen, China   19 Apr 2018   

Research Grants & Projects

 
Translational selection and Drosophila genome evolution
US National Science Foundation: 
Project Year: Jun 2003 - May 2008    Investigator(s): Hiroshi Akashi
Natural Selection
Alfred P. Sloan Foundation: Young Investigator Award in Molecular Studies of Evolution
Project Year: Sep 1996 - Aug 1998    Investigator(s): Hiroshi Akashi