明石裕 (Hiroshi Akashi) - マイポータル - researchmap

基本情報

所属: 国立遺伝学研究所

学位: PhD(University of Chicago, USA)
BA(Harvard University, USA)

J-GLOBAL ID: 201201005898606037
researchmap会員ID: B000222005

外部リンク: http://www.nig.ac.jp/labs/EvoGen/

研究キーワード

4

研究分野

1

ライフサイエンス / 進化生物学 / genome adaptation and evolution

経歴

6

2009年1月 - 現在

国立遺伝学研究所
2006年7月 - 2008年12月

Penn State University, Department of Biology, Associate Professor
2000年8月 - 2006年6月

Penn State University, Department of Biology, Assistant Professor
1998年8月 - 2000年7月

University of Kansas, Department of Ecology and Evolutionary Biology, Assistant Professor
1996年9月 - 1998年8月

University of California, Davis, Section of Evolution and Ecology, Visiting Scholar
1996年2月 - 1996年8月

University of California, Davis, Center for Population Biology, Postdoctoral Fellow

学歴

2

1985年8月 - 1990年1月

Harvard College, Biology
University of Chicago, Ecology and Evolution, MS/PhD

委員歴

4

2020年1月 - 現在

Genes & Genetic Systems, Editorial Board
2018年2月 - 現在

PCI Evolutionary Biology, Recommender
2010年7月 - 現在

BMC Genomics, Associate Editor
2004年1月 - 現在

Faculty of 1000 Biology, Contributing Faculty Member for

受賞

4

1998年6月

Young Investigator Award, American Society of Naturalists

Hiroshi Akashi
1996年9月

Young Investigator Award in Molecular Studies of Evolution, Alfred P. Sloan Foundation

Hiroshi Akashi
1996年1月

Departmental Award for Outstanding Performance in the General Field of Ecology and Evolution, University of Chicago

Hiroshi Akashi
1990年1月

magna cum laude with highest honors in the Department of Biology, Harvard College

Hiroshi Akashi

論文

28

Distinguishing among evolutionary forces acting on Genome-Wide base composition: Computer simulation analysis of approximate methods for inferring site frequency spectra of derived mutations

Tomotaka Matsumoto, Hiroshi Akashi

G3: Genes, Genomes, Genetics 8(5) 1755-1769 2018年5月1日査読有り
Codon Usage Selection Can Bias Estimation of the Fraction of Adaptive Amino Acid Fixations

Tomotaka Matsumoto, Anoop John, Pablo Baeza-Centurion, Boyang Li, Hiroshi Akashi

MOLECULAR BIOLOGY AND EVOLUTION 33(6) 1580-1589 2016年6月査読有り
Evaluation of Ancestral Sequence Reconstruction Methods to Infer Nonstationary Patterns of Nucleotide Substitution

Tomotaka Matsumoto, Hiroshi Akashi, Ziheng Yang

GENETICS 200(3) 873-+ 2015年7月査読有り
Assembly constraints drive co-evolution among ribosomal constituents

Saurav Mallik, Hiroshi Akashi, Sudip Kundu

NUCLEIC ACIDS RESEARCH 43(11) 5352-5363 2015年6月査読有り
Weak Selection and Protein Evolution

Hiroshi Akashi, Naoki Osada, Tomoko Ohta

GENETICS 192(1) 15-U43 2012年9月査読有り
Mitochondrial-Nuclear Interactions and Accelerated Compensatory Evolution: Evidence from the Primate Cytochrome c Oxidase Complex

Naoki Osada, Hiroshi Akashi

MOLECULAR BIOLOGY AND EVOLUTION 29(1) 337-346 2012年1月査読有り
Do Amino Acid Biosynthetic Costs Constrain Protein Evolution in Saccharomyces cerevisiae?

Douglas W. Raiford, Esley M. Heizer, Robert V. Miller, Hiroshi Akashi, Michael L. Raymer, Dan E. Krane

JOURNAL OF MOLECULAR EVOLUTION 67(6) 621-630 2008年12月査読有り
Evolution of genes and genomes on the Drosophila phylogeny

Andrew G. Clark, Michael B. Eisen, Douglas R. Smith, Casey M. Bergman, Brian Oliver, Therese A. Markow, Thomas C. Kaufman, Manolis Kellis, William Gelbart, Venky N. Iyer …

NATURE 450(7167) 203-218 2007年11月査読有り
Ancestral Inference and the Study of Codon Bias Evolution: Implications for Molecular Evolutionary Analyses of the Drosophila melanogaster Subgroup

Hiroshi Akashi, Piyush Goel, Anoop John

PLOS ONE 2(10) e1065 2007年10月査読有り
Strong regional heterogeneity in base composition evolution on the Drosophila X chromosome

Wen-Ya Ko, Shengfu Piao, Hiroshi Akashi

GENETICS 174(1) 349-362 2006年9月査読有り
Molecular evolution in the Drosophila melanogaster species subgroup: Frequent parameter fluctuations on the timescale of molecular divergence

H Akashi, WY Ko, SF Piao, A John, P Goel, CF Lin, AP Vitins

GENETICS 172(3) 1711-1726 2006年3月査読有り
Molecular phylogeny of the Drosophila melanogaster species subgroup

WY Ko, RM David, H Akashi

JOURNAL OF MOLECULAR EVOLUTION 57(5) 562-573 2003年11月査読有り
Translational selection and yeast proteome evolution

H Akashi

GENETICS 164(4) 1291-1303 2003年8月査読有り
Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis

H Akashi, T Gojobori

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(6) 3695-3700 2002年3月査読有り
Gene expression and molecular evolution

H Akashi

CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6) 660-666 2001年12月査読有り
A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes

K Iida, H Akashi

GENE 261(1) 93-105 2000年12月査読有り
Within- and between-species DNA sequence variation and the 'footprint' of natural selection

H Akashi

GENE 238(1) 39-51 1999年9月査読有り
Inferring the fitness effects of DNA mutations from polymorphism and divergence data: Statistical power to detect directional selection under stationarity and free recombination

H Akashi

GENETICS 151(1) 221-238 1999年1月査読有り
Translational selection and molecular evolution

H Akashi, A Eyre-Walker

CURRENT OPINION IN GENETICS & DEVELOPMENT 8(6) 688-693 1998年12月査読有り
Mutation pressure, natural selection, and the evolution of base composition in Drosophila

H Akashi, RM Kliman, A Eyre-Walker

GENETICA 102-3 49-60 1998年査読有り

もっとみる

書籍等出版物

2

Urban Resilience A Transformative Approach Y. Yamagata & H. Maruyama (Eds.), Chapter 10 Disease Outbreaks: Critical Biological Factors

(担当:共著, 範囲:Chapter 10 Disease Outbreaks: Critical Biological Factors)

Springer 2016年10月
Encyclopedia of Evolutionary Biology 1st Edition

(担当:共編者(共編著者))

Academic Press 2016年5月 (ISBN: 012800049X)

講演・口頭発表等

14

Population genomics of weak selection and lineage specific evolution in Drosophila

明石裕

International Symposium on Evolutionary Genomics and Bioinformatics, National Taiwan University, Taiwan 2018年10月22日
A new approach to estimate site frequency spectrum: application to infer evolutionary forces on base composition in Drosophila genomes

Symposium on Evolutionary Genetics and Omics, Mishima, Japan 2018年7月14日招待有り
Approximate method for inferring site frequency spectra of polymorphism in recombining regions

Society for Molecular Biology and Evolution (SMBE) 2018, Yokohama, Japan 2018年7月9日
’Hitchhiking’ and adaptive protein evolution: Why do fast-evolving proteins show reduced codon usage bias in Drosophila

明石裕

International Symposium of Evolution of Genes and Genomes, Chengdu, China 2018年4月23日
’Hitchhiking’ and adaptive protein evolution: Why do fast-evolving proteins show reduced codon usage bias in Drosophila

明石裕

The 1st AsiaEvo Conference, Shenzhen, China 2018年4月19日招待有り
Codon usage selection biases estimates of the fraction of adaptive amino acid substitutions

Genome Evolution at Mishima 2017年11月29日
集団内多型を用いた祖先ゲノム配列の推定

89th Meeting of the Genetics Society of Japan 2017年9月14日
集団内多型を用いた祖先ゲノム配列の推定

89th Meeting of the Genetics Society of Japan 2017年9月13日
Inferring the prevalence of adaptive evolution: Biases from codon usage selection

明石裕

Genome Evolution at Mishima 2017年3月28日招待有り
The global population genetics of Dengue viruses revealed through temporal and spatial mapping of viral genetic variation

International Meeting on Emerging Diseases and Surveillance 2016年11月4日
Testing natural selection in Drosophila intron evolution

The 88th Annual Meeting of the Genetics Society of Japan 2016年9月7日
Transcription and within-gene base composition heterogeneity in D. melanogaster

The 88th Annual Meeting of the Genetics Society of Japan 2016年9月7日
Inferring the prevalence of adaptive evolution from polymorphism/divergence data: Biases from codon usage selection

Germany & Japan Workshop on Evolutionary Genomics 2016年3月22日招待有り
Simulating Pathogen Emergence and Molecular Evolution using Individual-based Network Models

Evolutionary Systems Biology: From Model Organisms to Human Disease 2016年3月2日

共同研究・競争的資金等の研究課題

2

Translational selection and Drosophila genome evolution

US National Science Foundation 2003年6月 - 2008年5月

Hiroshi Akashi
Natural Selection

Alfred P. Sloan Foundation Young Investigator Award in Molecular Studies of Evolution 1996年9月 - 1998年8月

Hiroshi Akashi