2019年
Sex differences in congenital heart disease in Down syndrome: study data from medical records and questionnaires in a region of Japan.
BMJ paediatrics open
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- 巻
- 3
- 号
- 1
- 開始ページ
- e000414
- 終了ページ
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1136/bmjpo-2018-000414
Reports indicate lower Down syndrome (DS) survival among females than among males in Australia, contrasting with female longevity in the general population. Using data on 1310 people with DS (626 females and 684 males) in Japan from five hospitals' medical records and questionnaires completed by parents of people with DS, we investigated sex differences in congenital heart disease (CHD), which may be related to mortality. The CHD rate was significantly higher for females (354, 57%) than for males (338, 49%; p=0.010). Significantly more females (199, 32%) than males (175, 26%) underwent surgery for CHD (p=0.018).
- リンク情報
- ID情報
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- DOI : 10.1136/bmjpo-2018-000414
- PubMed ID : 31321317
- PubMed Central 記事ID : PMC6598551