2016年11月
A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan
Experimental Animals
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- 開始ページ
- 345
- 終了ページ
- 351
- DOI
- 10.1538/expanim.16-0022
- 出版者・発行元
- 公益社団法人 日本実験動物学会
Animal models of thrombocytopenia are indispensable for evaluating the in vivo efficacy of hemostatic agents, cryopreserved platelets, and artificial platelets, but no large animal models are available. In this study, we generated a swine model of acute thrombocytopenia with prolonged bleeding times by administering the chemotherapeutic drug busulfan. First, we tested multiple doses of busulfan (4
- リンク情報
- ID情報
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- DOI : 10.1538/expanim.16-0022
- ISSN : 1341-1357
- CiNii Articles ID : 130005158860
- PubMed ID : 27333841