論文

査読有り
2018年1月

Absence of adventitial vasa vasorum formation at the coronary segment with myocardial bridge - An optical coherence tomography study

INTERNATIONAL JOURNAL OF CARDIOLOGY
  • Kensuke Nishimiya
  • ,
  • Yasuharu Matsumoto
  • ,
  • Hongxin Wang
  • ,
  • Zhonglie Piao
  • ,
  • Kazuma Ohyama
  • ,
  • Hironori Uzuka
  • ,
  • Kiyotaka Hao
  • ,
  • Ryuji Tsuburaya
  • ,
  • Jun Takahashi
  • ,
  • Kenta Ito
  • ,
  • Hiroaki Shimokawa

250
開始ページ
275
終了ページ
277
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ijcard.2017.09.211
出版者・発行元
ELSEVIER IRELAND LTD

Background: Myocardial bridge (MB) is a myocardial bundle through which coronary segment tunnels and could compress coronary arteries causing myocardial ischemia. However, the characteristic structural findings of MB remain to be fully elucidated. Recently, we demonstrated that optical coherence tomography (OCT) enables us to visualize adventitial vasa vasorum (VV) formation in humans. In this study, we examined adventitial VV formation at the coronary segment with MB in humans using OCT.
Methods: We examined 15 consecutive patients with suspected angina pectoris and MB in the left anterior descending (LAD) coronary arteries but no angiographic coronary stenosis. MB was detected on coronary angiography as a segment with milking effect. We performed intracoronary OCT imaging along the entire LAD. Morphometric analysis was performed at MB and proximal/distal segments at every 1 mm.
Results: OCT examination showed the absence of adventitial VV formation at MB in the LAD, while VV was clearly noted at both the proximal and distal reference segments. Adventitial VV area was significantly less at MB compared with the proximal or distal references.
Conclusions: These results with OCT imaging indicate that coronary segments with MB lack adventitial VV formation in humans, suggesting that MB could influence morphological and functional changes of the coronary artery. (C) 2017 Published by Elsevier Ireland Ltd.

Web of Science ® 被引用回数 : 8

リンク情報
DOI
https://doi.org/10.1016/j.ijcard.2017.09.211
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28993001
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000415822100055&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.ijcard.2017.09.211
  • ISSN : 0167-5273
  • eISSN : 1874-1754
  • PubMed ID : 28993001
  • Web of Science ID : WOS:000415822100055

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