原田卓 (Harada Suguru) - マイポータル

基本情報

所属: 奈良県立医科大学血栓止血医薬生物学共同研究講座招聘助教
: 中外製薬株式会社研究員

学位: 博士（工学）(東京農工大学大学院)

研究者番号: 60836013
J-GLOBAL ID: 201801008049758277
researchmap会員ID: B000310179

論文

Cisplatin Augments Antitumor T-Cell Responses Leading to a Potent Therapeutic Effect in Combination With PD-L1 Blockade.

Wakita D, Iwai T, Harada S, Suzuki M, Yamamoto K, Sugimoto M

Anticancer research 39(4) 1749-1760 2019年4月査読有り
Continuous administration of bevacizumab plus capecitabine, even after acquired resistance to bevacizumab, restored anti-angiogenic and antitumor effect in a human colorectal cancer xenograft model

Toshiki Iwai, Masamichi Sugimoto, Suguru Harada, Keigo Yorozu, Mitsue Kurasawa, Kaname Yamamoto

ONCOLOGY REPORTS 36(2) 626-632 2016年8月査読有り
Superior antitumor activity of trastuzumab combined with capecitabine plus oxaliplatin in a human epidermal growth factor receptor 2-positive human gastric cancer xenograft model.

Harada S, Yanagisawa M, Kaneko S, Yorozu K, Yamamoto K, Moriya Y, Harada N

Molecular and clinical oncology 3(5) 987-994 2015年9月査読有り
Eldecalcitol replaces endogenous calcitriol but does not fully compensate for its action in vivo

Hitoshi Saito, Suguru Harada

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 144 189-196 2014年10月査読有り
A series of nonsecosteroidal vitamin D receptor agonists for osteoporosis therapy

Hirotaka Kashiwagi, Yoshiyuki Ono, Masateru Ohta, Susumu Itoh, Fumihiko Ichikawa, Suguru Harada, Satoshi Takeda, Nobuo Sekiguchi, Masaki Ishigai, Tadakatsu Takahashi

Bioorganic and Medicinal Chemistry 21(7) 1823-1833 2013年4月1日査読有り
Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment

Atsushi Arai, Toshihide Mizoguchi, Suguru Harada, Yasuhiro Kobayashi, Yuko Nakamichi, Hisataka Yasuda, Josef M. Penninger, Kazuhiro Yamada, Nobuyuki Udagawa, Naoyuki Takahashi

JOURNAL OF CELL SCIENCE 125(12) 2910-2917 2012年6月査読有り
Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone

Suguru Harada, Toshihide Mizoguchi, Yasuhiro Kobayashi, Yuko Nakamichi, Satoshi Takeda, Sadaoki Sakai, Fumiaki Takahashi, Hitoshi Saito, Hisataka Yasuda, Nobuyuki Udagawa …

JOURNAL OF BONE AND MINERAL RESEARCH 27(2) 461-473 2012年2月査読有り
Lineage-Committed Osteoclast Precursors Circulate in Blood and Settle Down Into Bone

Akinori Muto, Toshihide Mizoguchi, Nobuyuki Udagawa, Susumu Ito, Ichiro Kawahara, Yoshimitsu Abiko, Atsushi Arai, Suguru Harada, Yasuhiro Kobayashi, Yuko Nakamichi …

JOURNAL OF BONE AND MINERAL RESEARCH 26(12) 2978-2990 2011年12月査読有り
[Frontiers in vitamin D; basic research and clinical application. Inhibitory effects of eldecalcitol, an active vitamin D derivative, on bone resorption in vivo].

Harada S, Mizoguchi T, Takahashi N

Clinical calcium 21(11) 91-98 2011年11月査読有り
Novel nonsecosteroidal vitamin D-3 carboxylic acid analogs for osteoporosis, and SAR analysis

Hirotaka Kashiwagi, Yoshiyuki Ono, Kazuki Shimizu, Tsuyoshi Haneishi, Susumu Ito, Shigeyuki Iijima, Takamitsu Kobayashi, Fumihiko Ichikawa, Suguru Harada, Hideki Sato …

BIOORGANIC & MEDICINAL CHEMISTRY 19(16) 4721-4729 2011年8月査読有り
[Control of bone resorption by RANKL-RANK system].

Harada S, Takahashi N

Clinical calcium 21(8) 1121-1130 2011年8月査読有り
Nobiletin, a polymethoxy flavonoid, suppresses bone resorption by inhibiting NFκB-dependent prostaglandin E synthesis in osteoblasts and prevents bone loss due to estrogen deficiency.

Harada S, Tominari T, Matsumoto C, Hirata M, Takita M, Inada M, Miyaura C

Journal of pharmacological sciences 115(1) 89-93 2011年1月査読有り
Eldecalcitol is less effective in suppressing parathyroid hormone compared to calcitriol in vivo

Suguru Harada, Satoshi Takeda, Akiko Uno, Fumiaki Takahashi, Hitoshi Saito

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 121(1-2) 281-283 2010年7月査読有り