論文

査読有り 国際誌
2018年3月1日

Quantification of the kV X-ray imaging dose during real-time tumor tracking and from three- and four-dimensional cone-beam computed tomography in lung cancer patients using a Monte Carlo simulation.

Journal of radiation research
  • Mitsuhiro Nakamura
  • ,
  • Yoshitomo Ishihara
  • ,
  • Yukinori Matsuo
  • ,
  • Yusuke Iizuka
  • ,
  • Nami Ueki
  • ,
  • Hiraku Iramina
  • ,
  • Hideaki Hirashima
  • ,
  • Takashi Mizowaki

59
2
開始ページ
173
終了ページ
181
記述言語
英語
掲載種別
DOI
10.1093/jrr/rrx098

Knowledge of the imaging doses delivered to patients and accurate dosimetry of the radiation to organs from various imaging procedures is becoming increasingly important for clinicians. The purposes of this study were to calculate imaging doses delivered to the organs of lung cancer patients during real-time tumor tracking (RTTT) with three-dimensional (3D), and four-dimensional (4D) cone-beam computed tomography (CBCT), using Monte Carlo techniques to simulate kV X-ray dose distributions delivered using the Vero4DRT. Imaging doses from RTTT, 3D-CBCT and 4D-CBCT were calculated with the planning CT images for nine lung cancer patients who underwent stereotactic body radiotherapy (SBRT) with RTTT. With RTTT, imaging doses from correlation modeling and from monitoring of imaging during beam delivery were calculated. With CBCT, doses from 3D-CBCT and 4D-CBCT were also simulated. The doses covering 2-cc volumes (D2cc) in correlation modeling were up to 9.3 cGy for soft tissues and 48.4 cGy for bone. The values from correlation modeling and monitoring were up to 11.0 cGy for soft tissues and 59.8 cGy for bone. Imaging doses in correlation modeling were larger with RTTT. On a single 4D-CBCT, the skin and bone D2cc values were in the ranges of 7.4-10.5 cGy and 33.5-58.1 cGy, respectively. The D2cc from 4D-CBCT was approximately double that from 3D-CBCT. Clinicians should Figure that the imaging dose increases the cumulative doses to organs.

リンク情報
DOI
https://doi.org/10.1093/jrr/rrx098
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29385514
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950977
ID情報
  • DOI : 10.1093/jrr/rrx098
  • PubMed ID : 29385514
  • PubMed Central 記事ID : PMC5950977

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