2016年7月
Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia
PSYCHIATRY INVESTIGATION
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- 巻
- 13
- 号
- 4
- 開始ページ
- 413
- 終了ページ
- 419
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.4306/pi.2016.13.4.413
- 出版者・発行元
- KOREAN NEUROPSYCHIATRIC ASSOC
Objective Medication adherence is important in the treatment of schizophrenia, and critical periods during treatment may be associated with relapse. However, the relationship between adherence and duration of outpatient treatment (DOT) remains unclear. The authors aimed to clarify the relationship between adherence and DOT at a psychiatric hospital in Japan.
Methods For outpatients with schizophrenia who regularly visit Shin-Abuyama hospital, the authors conducted a single questionnaire survey (five questions covering gender, age, DOT, medication shortages, and residual medication) over one month period. Participants were divided into two groups whether DOT were from more than one year to within five years or not. Mantel-Haenszel analysis and logistic regression analysis were performed on the data regarding the medication adherence.
Results Effective answers were received for 328 patients. The residual medication rate was significantly higher among those receiving outpatient treatment from more than one year to within five years than five years than those receiving outpatient treatment for more than five years or less than one year (p=0.016).
Conclusion This survey suggests that there are critical periods during which patients are most prone to poor adherence. Because poor adherence increases the risk of relapse, specific measures must be taken to improve adherence during these periods.
Methods For outpatients with schizophrenia who regularly visit Shin-Abuyama hospital, the authors conducted a single questionnaire survey (five questions covering gender, age, DOT, medication shortages, and residual medication) over one month period. Participants were divided into two groups whether DOT were from more than one year to within five years or not. Mantel-Haenszel analysis and logistic regression analysis were performed on the data regarding the medication adherence.
Results Effective answers were received for 328 patients. The residual medication rate was significantly higher among those receiving outpatient treatment from more than one year to within five years than five years than those receiving outpatient treatment for more than five years or less than one year (p=0.016).
Conclusion This survey suggests that there are critical periods during which patients are most prone to poor adherence. Because poor adherence increases the risk of relapse, specific measures must be taken to improve adherence during these periods.
- リンク情報
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- DOI
- https://doi.org/10.4306/pi.2016.13.4.413
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201702211348841420
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/27482242
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000380733300006&DestApp=WOS_CPL
- ID情報
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- DOI : 10.4306/pi.2016.13.4.413
- ISSN : 1738-3684
- eISSN : 1976-3026
- J-Global ID : 201702211348841420
- PubMed ID : 27482242
- Web of Science ID : WOS:000380733300006