Hidehito Saito-Takatsuji

Profile Information

Affiliation: School of Medicine, Kanazawa Medical University

Degree: Ph.D in Medicine
修士(医学)

J-GLOBAL ID: 201801016723006351
researchmap Member ID: B000346553

Research Areas

Life sciences / Medical biochemistry /

Awards

Jul, 2017

Generation of Induced Pluripotent Stem Cells from Human Melanoma Tumor-infiltrating Lymphocytes.
Jul, 2017

金沢医科大学医学会「論文表彰」, Generation of Induced Pluripotent Stem Cells from Human Melanoma Tumor-infiltrating Lymphocytes., 金沢医科大学医学会

高辻英仁

Papers

EPAC2 acts as a negative regulator in Matrigel-driven tubulogenesis of human microvascular endothelial cells.

Takayuki Ikeda, Yoshino Yoshitake, Yasuo Yoshitomi, Hidehito Saito-Takatsuji, Yasuhito Ishigaki, Hideto Yonekura

Scientific reports, 11(1) 19453-19453, Sep 30, 2021
Protective Effects of Collagen Tripeptides in Human Aortic Endothelial Cells by Restoring ROS-Induced Transcriptional Repression.

Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Yasuhito Ishigaki, Shoko Yamamoto, Noriaki Numata, Yasuo Sakai, Masayoshi Takeuchi, Naohisa Tomosugi, Shogo Katsuda, Hideto Yonekura …

Nutrients, 13(7), Jun 29, 2021
Emerging Role of AP-1 Transcription Factor JunB in Angiogenesis and Vascular Development

Yasuo Yoshitomi, Takayuki Ikeda, Hidehito Saito-Takatsuji, Hideto Yonekura

International Journal of Molecular Sciences, 22(6) 2804-2804, Mar 10, 2021
Role of Arginine Methylation in Alternative Polyadenylation of VEGFR-1 (Flt-1) pre-mRNA

Takayuki Ikeda, Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Hideto Yonekura

International Journal of Molecular Sciences, 21(18) 6460, Sep, 2020 Peer-reviewed
CX3CR1-CD8+ T cells are critical in antitumor efficacy but functionally suppressed in the tumor microenvironment

(Takayoshi Yamauchi), Toshifumi Hoki, Takaaki Oba, Hidehito Saito, Kristopher Attwood, Michael S Sabel, Alfred E Chang, Kunle Odunsi, Fumito Ito

JCI insight, 5(8) e133920, Apr, 2020 Peer-reviewed
Ultraviolet B-induced Otx2 expression in lens epithelial cells promotes epithelial-mesenchymal transition

Yoshitomi Y, Osada H, Satake H, Kojima M, Saito-Takatsuji H, Ikeda T, Yoshitake Y, Ishigaki Y, Kubo E, Sasaki H, Yonekura H

Biology Open, 8(2) bio035691, Feb, 2019 Peer-reviewed
JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin

Yasuo Yoshitomi, Takayuki Ikeda, Hidehito Saito, Yoshino Yoshitake, Yasuhito Ishigaki, Toshihisa Hatta, Nobuo Kato, Hideto Yonekura

Journal of Cell Science, 130(5) 916-926, 2017 Peer-reviewed
Generation of induced pluripotent stem cells from human melanoma tumor-infiltrating lymphocytes

H.Saito, K.Iwabuchi, N.Fusaki, F. Ito

Journal of Visualized Experiments, 117 e54375-e54375, Nov, 2016 Peer-reviewed
Adoptive transfer of CD8+ T cells generated from induced pluripotent stem cells triggers regressions of large tumors along with immunological memory

H.Saito, K.Okita, AE.Chang, F.Ito

Cancer Research, 76(12) 3473-3483, Jun, 2016 Peer-reviewed
Reprogramming of melanoma tumor-infiltrating lymphocytes to induced pluripotent stem cells.

H.Saito, K.Okita, N.Fusaki, MS.Sabel, AE.Chang, F.Ito

Stem Cells International, 2016 8394960-**, Jan, 2016 Peer-reviewed
Regulation of soluble Flt-1(VEGFR-1) production by hnRNP D and protein arginine methylation

T.Ikeda, Y.Yoshitomi, H.Saito, T.Shimasaki, H.Yamaya, T.Kobata, Y.Ishigaki, N.Tomosugi, Y.Yoshitake, H.Yonekura

Molecular and Cellular Biochemistry, 413(1-2) 155-164, 2016 Peer-reviewed
Regulation of soluble Flt-1(VEGFR-1) production by hnRNP D and protein arginine methylation

T.Ikeda, Y.Yoshitomi, H.Saito, T.Shimasaki, H.Yamaya, T.Kobata, Y.Ishigaki, N.Tomosugi, Y.Yoshitake, H.Yonekura

Molecular and Cellular Biochemistry, 413(1-2) 155-164, 2016 Peer-reviewed
cAMP ameliorates inflammation by modulation of macrophage receptor for advanced glycation end-products.

(S.Motoyoshi), Y.Yamamoto, S.Munesue, H.Igawa, A.Harashima,H.Saito, D.Han, T.Watanabe, H.Sato, H.Yamamoto

Biochemical Journal, 463(1) 75-82, Oct, 2014 Peer-reviewed
Sivelestat sodium hydrate inhibits neutrophil migration to the vessel wall and suppresses hepatic ischemia-reperfusion injury.

(S.Sakai), H.Tajima, T.Miyashita, S.Nakanuma, I.Makino, H.Hayashi, H.Nakagawara, H.Kitagawa, S.Fushida, T.Fujimura, H.Saito, S.Munesue, Y.Yamamoto, T.Ohta

Digestive Diseases and Sciences, 59(4) 787-794, Apr, 2014 Peer-reviewed
Low-molecular weight fractions of japanese soy sauce act as a rage antagonist via inhibition of rage trafficking to lipid rafts.

(S.Munesue), Y.Yamamoto, R.Urushihara, K.Inomata, H.Saito, S.Motoyoshi, T.Watanabe, H.Yonekura, H.Yamamoto

Food & Function, 4(12) 1835-1842, Dec, 2013 Peer-reviewed
Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic beta-cell failure in type 2 diabetes.

(D.Han), Y.Yamamoto, S.Munesue, S.Motoyoshi, H.Saito, MT.Win, T.Watanabe, K.Tsuneyama, H.Yamamoto

Genes to Cells, 18(4) 302-314, Apr, 2013 Peer-reviewed
Diabetes alters subsets of endothelial progenitor cells that reside in blood, bone marrow, and spleen.

H.Saito, Y.Yamamoto, H.Yamamoto

American Journal of Physiology - Cell Physiology, 302(6) C892-C901, May, 2012 Peer-reviewed
Regulation of rage for attenuating progression of diabetic vascular complications.

(MT.Win), Y.Yamamoto, S.Munesue, H.Saito, D.Han, S.Motoyoshi, T.Kamal, T.Ohara, T.Watanabe, H.Yamamoto.

Journal of Diabetes Research, 2012 8-8, Jan, 2012 Peer-reviewed
Septic shock is associated with receptor for advanced glycation end products ligation of lps.

(Y.Yamamoto), A.Harashima, H.Saito, K.Tsuneyama, S.Munesue, S.Motoyoshi, D.Han, T.Watanabe, M.Asano, S.Takasawa, H.Okamoto, S.Shimura, T.Karasawa, H.Yonekura, H.Yamamoto

Journal of Immunology, 186(5) 3248-3257, Mar, 2011
Rage in diabetic nephropathy.

(H.Yamamoto), T.Watanabe, Y.Yamamoto, H.Yonekura, S.Munesue, A.Harashima, K.Ooe, S.Hossain, H.Saito, N.Murakami

Current Molecular Medicine, 7(8) 752-757, Dec, 2007 Peer-reviewed

Presentations

うつモデルマウスの脳海馬で発現変動する遺伝子の探索と役割の解明

高辻英仁, 吉冨泰央, 池田崇之, 山本亮, 加藤伸郎, 米倉秀人

第39回分子病理研究会, Jul 8, 2022
Ultraviolet B-induced Otx2 in lens epithelial cells inhibits lens fiber gene expression and promotes epithelial-mesenchymal transition

Yasuo Yoshitomi, Hiromi Osada, Takayuki Ikeda, Hidehito Takatsuji, Hiroshi Sasaki, Hideto Yonekura

The 42nd Annual Meeting of the Molecular Biology Society of Japan, Dec 6, 2019
Role of Rheb interacting proteins in mTORC1 signaling pathway

Takayuki Ikeda,Yasuo Yoshitomi,Hidehito Saito-Takatsuji,Ken Inoki,Hideto Yonekura

The 92nd annual meeeting of the japanese biochemical society, Sep 18, 2019
UVB照射により水晶体上皮細胞に誘導されるOtx2は上皮間葉転換(EMT)を誘導して水晶体上皮細胞の水晶体繊維への分化を抑制する

Nov 30, 2018
UV照射により水晶体上皮細胞で誘導されるOtx2の機能解析

Sep 24, 2018
UV照射により水晶体上皮細胞で誘導されるOtx2の機能解析

吉冨泰央, 長田ひろみ, 佐竹悠, 高辻英仁, 池田崇之, 石山尚史, 石垣靖人, 久保江理, 佐々木洋, 米倉秀人

第57回日本白内障学会総会, 第44回水晶体研究会, Jul 20, 2018
JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin

Y.Yoshitomi, H.Takatsuji, T.Ikeda, H.Satake, N.Ishiyama, H.Yonekura

The 90st Annual Meeting of the Japanese Biochemical Society, Dec 6, 2017

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