基本情報

所属
京都府立医科大学 眼科学教室 病院助教

研究者番号
40982707
J-GLOBAL ID
202301013127810748
researchmap会員ID
R000057760

Dr. Deguchi graduated from Kyoto Prefectural University of Medicine in 2013. He joined the Department of Ophthalmology at the same university in 2015. In 2016, he began working as a medical staff member at Baptist Eye Institute, followed by a position at Machida Hospital starting in October 2017. In 2019, he enrolled in the graduate school of medical research at Kyoto Prefectural University of Medicine and completed his studies in 2023. As of April 2023, he serves as an Assistant Professor in the Department of Ophthalmology at Kyoto Prefectural University of Medicine. Throughout his career, Dr. Deguchi has consistently focused on research related to the cornea and uveitis among other ophthalmic conditions. In 2015, he compiled data on the postoperative outcomes of trabeculotomy, a glaucoma surgery, spanning the past 20 years. While working at Baptist Eye Clinic from 2016, he was engaged in the perioperative management of numerous corneal transplants and the diagnosis of corneal diseases. He also contributed to reports on cases diagnosed with intraocular lymphoma using retinal biopsy, as well as a case where steroid pulse therapy was notably effective in treating autoimmune retinopathy. Furthermore, he reported on studies comparing antibiotic resistance in ocular surface infections to that from 10 years prior. Since entering graduate school in 2019, he has been involved in basic and clinical research aimed at the clinical application of human-cultured corneal endothelial anterior chamber injection therapy. In 2020, he reported four cases of chemical injuries treated with cultivated allogenic corneal limbal epithelial transplantation and subsequent penetrating keratoplasty. He also reported a strong correlation between the quality of cultured corneal endothelial cells and the expression of ion transporters. In 2021, he discovered the presence of primary cilia in the corneal endothelial cells extracted from patients during corneal transplantation. In 2022, he reported on the correlation between the positivity rate of conjunctival and nasal cultures for methicillin-resistant Staphylococcus aureus. Additionally, he noted the significant role of intracellular pH in maintaining mitochondrial function in human-cultured corneal endothelium, for which he was awarded the 20th Japanese Corneal Society Research Award. His current research focuses primarily on elucidating the relationship between uveitis and immunosenescence / the role of cellular senescence in refractory ocular surface diseases.


経歴

  6

論文

  14

MISC

  13