Jan 8, 2018
Available, Bed-sided, Comprehensive (ABC) score to a diagnosis of Methicillin-resistant Staphylococcus aureus infection: A derivation and validation study
BMC Infectious Diseases
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- Volume
- 18
- Number
- 1
- First page
- 19
- Last page
- 19
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1186/s12879-017-2919-2
- Publisher
- BioMed Central Ltd.
Background: Methicillin-resistant Staphylococcus aureus (MRSA) infections continue to be a leading problem in health care facilities worldwide. Methods: This single-center retrospective cohort study consisted of a derivation phase and a validation phase. The derivation phase included all patients admitted to Osaka University Hospital between May 2010 and April 2011. We proposed a provisional available, bed-sided, comprehensive (ABC) score, and evaluated its accuracy using the clinical diagnosis as a reference. We subsequently revised ABC scores based on k coefficient scores of each variable this revision was validated by applying it to another patient population. Results: A total of 172 patients and 154 cases were enrolled in the derivation and validation studies, respectively. The revised ABC score consisted of four simple variables: type of clinical specimen (1 to 3 points), Gram-staining result (1 point), presence of local inflammation (2 points), and a systemic inflammatory response (2 points). A revised score of ≥5 points was sensitive (93.8%) and specific (90.6%), and the area under the receiver-operating curve was 0.969 (95% CI
0.957-1). Conclusions: We developed a simple and comprehensive scoring system for diagnosis of nosocomial MRSA infections
this system is applicable in a wide variety of situations.
0.957-1). Conclusions: We developed a simple and comprehensive scoring system for diagnosis of nosocomial MRSA infections
this system is applicable in a wide variety of situations.
- Link information
- ID information
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- DOI : 10.1186/s12879-017-2919-2
- ISSN : 1471-2334
- Pubmed ID : 29310586
- Pubmed Central ID : PMC5759200
- SCOPUS ID : 85040359388