Oct, 2015
Cytomegalovirus as an Insidious Pathogen Causing Duodenitis
ACTA MEDICA OKAYAMA
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- Volume
- 69
- Number
- 5
- First page
- 319
- Last page
- 323
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.18926/AMO/53679
- Publisher
- OKAYAMA UNIV MED SCHOOL
A 60-year-old woman with rheumatoid arthritis treated with methotrexate for a decade complained of slight epigastric discomfort. A positive cytomegalovirus (CMV) antigenemia test indicated the probability of CMV-related gastrointestinal infection, for which esophagogastroduodenoscopy was performed. Endoscopic findings showed a non-specific duodenal mucosal lesion; however, pathological investigation revealed evidence of CMV duodenitis. There is scarce information on the clinical and pathological features of CMV-related duodenitis, likely due to its low prevalence. CMV infection in the upper gastrointestinal tract should be considered as a differential diagnosis in high-risk individuals, particularly those with symptoms relating to the digestive system. Biopsy examinations are preferable for the definitive diagnosis of CMV gastrointestinal infection, even without specific endoscopic features.
- Link information
- ID information
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- DOI : 10.18926/AMO/53679
- ISSN : 0386-300X
- Pubmed ID : 26490030
- Web of Science ID : WOS:000365519600009