Papers

International journal
Aug, 2021

High-Dose Corticosteroids for a Pregnant Woman Critically Ill With Coronavirus Disease 2019.

Cureus
  • Koichiro Yamamoto
  • ,
  • Hideharu Hagiya
  • ,
  • Jota Maki
  • ,
  • Shuji Okahara
  • ,
  • Kou Hasegawa
  • ,
  • Fumio Otsuka

Volume
13
Number
8
First page
e17398
Last page
Language
English
Publishing type
DOI
10.7759/cureus.17398

Pregnancy was reported to be a risk factor for coronavirus disease 2019 (COVID-19), with an increased risk for premature birth. Corticosteroids and remdesivir are used for patients with COVID-19; however, there is no established treatment for these patients. In particular, the effective management of pregnant, critically ill patients with COVID-19 remains unknown. We describe a 34-year-old, critically ill woman at 30 weeks of gestation with COVID-19, who was successfully treated with remdesivir and combined high-dose betamethasone (12 mg/day for two days) and methylprednisolone (125 mg/day for three days) followed by steroid tapering. During treatment, fetal biophysical profile scores on obstetric ultrasound were normal; her pregnancy course progressed well. Since high-dose corticosteroids improve fetal lung maturation and as well as cytokine storm due to COVID-19, this case provides an insight into the management of pregnant COVID-19 patients.

Link information
DOI
https://doi.org/10.7759/cureus.17398
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34584807
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457894
ID information
  • DOI : 10.7759/cureus.17398
  • Pubmed ID : 34584807
  • Pubmed Central ID : PMC8457894

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