論文

2023年5月25日

Relationship between Abnormal Placenta and Obstetric Outcomes: A Meta-Analysis

Biomedicines
  • Shinya Matsuzaki
  • Yutaka Ueda
  • Satoko Matsuzaki
  • Hitomi Sakaguchi
  • Mamoru Kakuda
  • Misooja Lee
  • Yuki Takemoto
  • Harue Hayashida
  • Michihide Maeda
  • Reisa Kakubari
  • Tsuyoshi Hisa
  • Seiji Mabuchi
  • Shoji Kamiura
  • 全て表示

11
6
開始ページ
1522
終了ページ
1522
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.3390/biomedicines11061522
出版者・発行元
MDPI AG

The placenta has several crucial physiological functions that help maintain a normal pregnancy. Although approximately 2–4% of pregnancies are complicated by abnormal placentas, obstetric outcomes remain understudied. This study aimed to determine the outcomes and prevalence of patients with abnormal placentas by conducting a systematic review of 48 studies published between 1974 and 2022. The cumulative prevalence of circumvallate placenta, succenturiate placenta, multilobed placenta, and placenta membranacea were 1.2%, 1.0%, 0.2%, and 0.004%, respectively. Pregnancies with a circumvallate placenta were associated with an increased rate of emergent cesarean delivery, preterm birth (PTB), and placental abruption compared to those without a circumvallate placenta. The succenturiate lobe of the placenta was associated with a higher rate of emergent cesarean delivery, whereas comparative results were observed in terms of PTB, placental abruption, and placenta previa in comparison to those without a succenturiate lobe of the placenta. A comparator study that examined the outcomes of multilobed placentas found that this data is usually unavailable. Patient-level analysis (n = 15) showed high-rates of abortion (40%), placenta accreta spectrum (40%), and a low term delivery rate (13.3%) in women with placenta membranacea. Although the current evidence is insufficient to draw a robust conclusion, abnormal placentas should be recognized as a high-risk factor for adverse outcomes during pregnancy.

リンク情報
DOI
https://doi.org/10.3390/biomedicines11061522
URL
https://www.mdpi.com/2227-9059/11/6/1522/pdf
ID情報
  • DOI : 10.3390/biomedicines11061522
  • eISSN : 2227-9059

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