平田真樹 (Maki Hirata) - マイポータル

基本情報

所属: 徳島大学大学院社会産業理工学研究部生物資源産業学域講師

J-GLOBAL ID: 202001012288852752
researchmap会員ID: R000013745

研究分野

ライフサイエンス / 動物生命科学 /

論文

GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system.

Fuminori Tanihara, Maki Hirata, Zhao Namula, Manita Wittayarat, Lanh Thi Kim Do, Qingyi Lin, Koki Takebayashi, Hiromasa Hara, Megumi Nagahara, Takeshige Otoi

Molecular biology reports 2023年4月26日
DEVELOPMENT AND GENOME MUTATION OF BOVINE ZYGOTES VITRIFIED BEFORE AND AFTER GENOME EDITING VIA ELECTROPORATION

Thanh Van Nguyen, Lanh Thi Kim Do, Zhao Namula, Qingyi Lin, Nanaka Torigoe, Megumi Nagahara, Maki Hirata, Fuminori Tanihara, Takeshige Otoi

Cryo-Letters 44(2) 118-122 2023年3月
Efficiency of genetic modification in gene-knockout sperm-derived zygotes followed by electroporation of guide RNA targeting the same gene.

Koki Takebayashi, Manita Wittayarat, Qingyi Lin, Nanaka Torigoe, Bin Liu, Maki Hirata, Megumi Nagahara, Fuminori Tanihara, Takeshige Otoi

Animal science journal = Nihon chikusan Gakkaiho 94(1) e13842 2023年査読有り
GEEP Method: An Optimized Electroporation-Mediated Gene Editing Approach for Establishment of Knockout Pig Lines.

Fuminori Tanihara, Maki Hirata, Takeshige Otoi

Methods in molecular biology (Clifton, N.J.) 2637 293-300 2023年招待有り
Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN.

Fuminori Tanihara, Maki Hirata, Zhao Namula, Lanh Thi Kim Do, Naoaki Yoshimura, Qingyi Lin, Koki Takebayashi, Tetsushi Sakuma, Takashi Yamamoto, Takeshige Otoi

Frontiers in cell and developmental biology 11 884340 2023年査読有り
GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system

Fuminori Tanihara, Maki Hirata, Zhao Namula, Manita Wittayarat, Lanh Thi Kim Do, Qingyi Lin, Koki Takebayashi, Hiromasa Hara, Megumi Nagahara, Takeshige Otoi

Molecular Biology Reports 2023年
Gene editing in porcine embryos using a combination of electroporation and transfection methods.

Koki Takebayashi, Manita Wittayarat, Qingyi Lin, Maki Hirata, Naoaki Yoshimura, Nanaka Torigoe, Megumi Nagahara, Lanh Thi Kim Do, Fuminori Tanihara, Takeshige Otoi

Reproduction in domestic animals = Zuchthygiene 57(10) 1136-1142 2022年10月
Multiple gene editing in porcine embryos using a combination of microinjection, electroporation, and transfection methods.

Quynh Anh Le, Manita Wittayarat, Zhao Namula, Qingyi Lin, Koki Takebayashi, Maki Hirata, Fuminori Tanihara, Lanh Thi Kim Do, Takeshige Otoi

Veterinary world 15(9) 2210-2216 2022年9月査読有り
Disruption of cell proliferation and apoptosis balance in the testes of crossbred cattle‐yaks affects spermatogenic cell fate and sterility

Megumi Shimazaki, Manita Wittayarat, Rentsenkhand Sambuu, Asami Sugita, Masaki Kawaguchi, Maki Hirata, Fuminori Tanihara, Mitsuhiro Takagi, Masayasu Taniguchi, Takeshige Otoi …

Reproduction in Domestic Animals 2022年6月6日
Effects of the timing of electroporation during in vitro maturation on triple gene editing in porcine embryos using CRISPR/Cas9 system.

Zhao Namula, Manita Wittayarat, Lanh Thi Kim Do, Thanh Van Nguyen, Qingyi Lin, Koki Takebayashi, Maki Hirata, Fuminori Tanihara, Takeshige Otoi

Veterinary and animal science 16 100241-100241 2022年6月
Viability and developmental potential of porcine blastocysts preserved for short term in a chemically defined medium at ambient temperature.

Qingyi Lin, Quynh Anh Le, Koki Takebayashi, Maki Hirata, Fuminori Tanihara, Chommanart Thongkittidilok, Osamu Sawamoto, Takeshi Kikuchi, Takeshige Otoi

Reproduction in domestic animals = Zuchthygiene 57(5) 556-563 2022年5月
Aberrant levels of DNA methylation and H3K9 acetylation in the testicular cells of crossbred cattle-yak showing infertility.

Praopilas Phakdeedindan, Manita Wittayarat, Theerawat Tharasanit, Mongkol Techakumphu, Megumi Shimazaki, Rentsenkhand Sambuu, Maki Hirata, Fuminori Tanihara, Masayasu Taniguchi, Takeshige Otoi …

Reproduction in domestic animals = Zuchthygiene 57(3) 304-313 2022年3月
Effects of individual or in-combination antioxidant supplementation during in vitro maturation culture on the developmental competence and quality of porcine embryos.

Chommanart Thongkittidilok, Quynh Anh Le, Qingyi Lin, Koki Takebayashi, Thi Kim Lanh Do, Zhao Namula, Maki Hirata, Fuminori Tanihara, Takeshige Otoi

Reproduction in domestic animals = Zuchthygiene 57(3) 314-320 2022年3月
Triple gene editing in porcine embryos using electroporation alone or in combination with microinjection.

Zhao Namula, Quynh Anh Le, Manita Wittayarat, Qingyi Lin, Koki Takebayashi, Maki Hirata, Lanh Thi Kim Do, Fuminori Tanihara, Takeshige Otoi

Veterinary world 15(2) 496-501 2022年2月
Zona pellucida treatment before CRISPR/Cas9-mediated genome editing of porcine zygotes.

Zhao Namula, Maki Hirata, Quynh Anh Le, Qingyi Lin, Koki Takebayashi, Naoaki Yoshimura, Fuminori Tanihara, Chommanart Thongkittidilok, Takeshige Otoi

Veterinary medicine and science 8(1) 164-169 2022年1月
Short-term preservation of porcine zygotes at ambient temperature using a chemically defined medium.

Qingyi Lin, Quynh Anh Le, Koki Takebayashi, Maki Hirata, Fuminori Tanihara, Osamu Sawamoto, Takeshi Kikuchi, Takeshige Otoi

Animal science journal = Nihon chikusan Gakkaiho 93(1) e13711 2022年1月
Generation of mutant pigs by lipofection-mediated genome editing in embryos.

Maki Hirata, Manita Wittayarat, Zhao Namula, Quynh Anh Le, Qingyi Lin, Koki Takebayashi, Chommanart Thongkittidilok, Taro Mito, Sayuri Tomonari, Fuminori Tanihara …

Scientific reports 11(1) 23806-23806 2021年12月13日
Development and characterization of Gal KO porcine bone marrow-derived mesenchymal stem cells.

Takeshi Kikuchi, Masuhiro Nishimura, Maki Hirata, Fuminori Tanihara, Natsuki Komori, Makoto Tanaka, Osamu Sawamoto, Takeshige Otoi, Shinichi Matsumoto

Xenotransplantation 28(6) e12717 2021年11月
Timing and duration of lipofection-mediated CRISPR/Cas9 delivery into porcine zygotes affect gene-editing events.

Qingyi Lin, Quynh Anh Le, Koki Takebayashi, Chommanart Thongkittidilok, Manita Wittayarat, Maki Hirata, Fuminori Tanihara, Takeshige Otoi

BMC research notes 14(1) 389-389 2021年10月9日
Current status of the application of gene editing in pigs.

Fuminori Tanihara, Maki Hirata, Takeshige Otoi

The Journal of reproduction and development 67(3) 177-187 2021年6月21日

もっとみる

共同研究・競争的資金等の研究課題

簡易なゲノム編集操作によるウイルス感染抵抗性動物の作出

日本学術振興会科学研究費助成事業基盤研究(B) 2022年4月 - 2025年3月

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気道・肺の障害・修復と再生におけるp53の役割～p53遺伝子改変ブタを用いた研究

日本学術振興会科学研究費助成事業基盤研究(C) 2018年4月 - 2023年3月

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ゲノム編集技術を用いた免疫不全マイクロミニブタの創出

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2018年4月 - 2021年3月

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日本学術振興会科学研究費助成事業特別研究員奨励費特別研究員奨励費 2003年 - 2005年

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