論文

査読有り 国際誌
2016年5月

A magnetic resonance imaging-based classification system for indication of trans-sphenoidal hypophysectomy in canine pituitary-dependent hypercortisolism.

The Journal of small animal practice
  • A Sato
  • ,
  • T Teshima
  • ,
  • H Ishino
  • ,
  • Y Harada
  • ,
  • T Yogo
  • ,
  • N Kanno
  • ,
  • D Hasegawa
  • ,
  • Y Hara

57
5
開始ページ
240
終了ページ
6
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/jsap.12474

OBJECTIVES: The objectives of this study were to establish a magnetic resonance imaging-based classification system for canine hyperadrenocorticism according to pituitary gland extension, determine indications for trans-sphenoidal hypophysectomy, and clarify the prognosis for each disease grade. METHODS: A 5-point classification system (Grades 1 to 5) was developed based on tumour extension in dorsal and cranio-caudal directions. Cases were then classified as Type A: no arterial circle of Willis or cavernous sinus involvement and Type B: cases in which these blood vessels were involved. RESULTS: Medical records and magnetic resonance imaging data of 37 cases with hyperadrenocorticism were reviewed. Thirty-three cases underwent surgery; 4 Grade 5 cases did not have appropriate indications for surgery, and other therapies were used. Complete resection was achieved for 3, 3, 22 and 1 Grade 1A, 2A, 3A and 3B cases, respectively. Resection was incomplete in 1, 1 and 2 Grade 3A, 3B and 4B cases, respectively. Remission was achieved in 29 cases. Recurrence occurred in 4 cases, all of which were classified as Grade 3. CLINICAL SIGNIFICANCE: Dogs with Type A, Grade 1 to 3 hyperadrenocorticism had a good prognosis following trans-sphenoidal hypophysectomy. Grade 3B, 4 and 5 cases may not be suitable for this surgery.

リンク情報
DOI
https://doi.org/10.1111/jsap.12474
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27101315
ID情報
  • DOI : 10.1111/jsap.12474
  • PubMed ID : 27101315

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