2017年
One-step micromolding of complex 3D microchambers for single-cell analysis
Lab on a Chip
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- 巻
- 17
- 号
- 4
- 開始ページ
- 647
- 終了ページ
- 652
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c6lc01313a
- 出版者・発行元
- Royal Society of Chemistry
Herein we examined the extent of replicability of the PDMS microchamber device transferred from the master mold with complex 3D structures fabricated via micro stereolithography. Due to the elastomeric properties of PDMS, the reversely tapered micromold, with the diameter ratio of ∼5 from the largest to the narrowest part, was precisely transferred without breaking. We obtained the mathematical model to estimate the stress exerted on the mold during the demolding process. Finally, we tested the applicability of this unusual microchamber for single-cell trapping and an enzyme assay.
- リンク情報
- ID情報
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- DOI : 10.1039/c6lc01313a
- ISSN : 1473-0189
- ISSN : 1473-0197
- SCOPUS ID : 85013104232