2015年8月
Oligodendrocyte generation during mouse development
GLIA
- ,
- 巻
- 63
- 号
- 8
- 開始ページ
- 1350
- 終了ページ
- 1356
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1002/glia.22863
- 出版者・発行元
- WILEY
Oligodendrocytes (OLs) are glial cells, which generate myelin in the central nervous system. Their interesting developmental features attract many neurobiologists eager to study cell differentiation, gene expression regulation, or dynamic morphogenesis. Their primary role in protecting the axons has major impacts in the medical research field: in multiple sclerosis, a demyelinating disease in which remyelination is blocked. Oligodendrogenesis is involved in higher brain function including motor skill learning and cognitive function. Here, we review advances in the research on OL development and highlight areas where questions remain to be answered in both developmental biology and neurobiology related aspects. GLIA 2015;63:1350-1356
- リンク情報
- ID情報
-
- DOI : 10.1002/glia.22863
- ISSN : 0894-1491
- eISSN : 1098-1136
- PubMed ID : 26013243
- Web of Science ID : WOS:000356385000007