2011年6月
Evolution Structural and functional diversity of cadherin at the adherens junction
JOURNAL OF CELL BIOLOGY
- ,
- 巻
- 193
- 号
- 7
- 開始ページ
- 1137
- 終了ページ
- 1146
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1083/jcb.201008173
- 出版者・発行元
- ROCKEFELLER UNIV PRESS
Adhesion between cells is essential to the evolution of multicellularity. Indeed, morphogenesis in animals requires firm but flexible intercellular adhesions that are mediated by subcellular structures like the adherens junction (AJ). A key component of AJs is classical cadherins, a group of transmembrane proteins that maintain dynamic cell-cell associations in many animal species. An evolutionary reconstruction of cadherin structure and function provides a comprehensive framework with which to appreciate the diversity of morphogenetic mechanisms in animals.
- リンク情報
- ID情報
-
- DOI : 10.1083/jcb.201008173
- ISSN : 0021-9525
- PubMed ID : 21708975
- Web of Science ID : WOS:000292135400003