論文

査読有り 国際誌
2019年6月21日

Emerging Role of Coronary Computed Tomography Angiography in Lipid-Lowering Therapy: a Bridge to Image-Guided Personalized Medicine.

Current cardiology reports
  • Toru Miyoshi
  • Kazuhiro Osawa
  • Keishi Ichikawa
  • Kazuki Suruga
  • Takashi Miki
  • Masashi Yoshida
  • Koji Nakagawa
  • Hironobu Toda
  • Kazufumi Nakamura
  • Hiroshi Morita
  • Hiroshi Ito
  • 全て表示

21
8
開始ページ
72
終了ページ
72
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s11886-019-1170-4

PURPOSE OF REVIEW: To summarize the current status of coronary computed tomography angiography (CTA) in the assessment of coronary plaques and discuss the ability of serial coronary CTA to quantitatively measure changes in the plaque burden in response to lipid-lowering therapy. RECENT FINDINGS: Recent advances in coronary CTA have allowed identification of high-risk coronary features in acute coronary syndrome and measurement of changes in the coronary plaque burden with good reproducibility. Statin therapy may delay plaque progression and change some plaque features. However, the clinical relevance of quantitative changes in coronary plaques and the optimal methods to reduce the plaque burden remain unclear. Despite guideline-directed lipid-lowering therapy, adverse events still occur in substantial numbers of patients receiving statins. Coronary CTA is noninvasive and has high diagnostic performance in patients with coronary artery disease, making change in the plaque burden an applicable biomarker for individualized assessment of future risk.

リンク情報
DOI
https://doi.org/10.1007/s11886-019-1170-4
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31228004
ID情報
  • DOI : 10.1007/s11886-019-1170-4
  • PubMed ID : 31228004

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