論文

査読有り
2022年11月

Paediatric lung transplantation: the impact of age on the survival.

Surgery today
  • Shinji Otani
  • Haruchika Yamamoto
  • Shin Tanaka
  • Yasuaki Tomioka
  • Kei Matsubara
  • Dai Shimizu
  • Toshio Shiotani
  • Ken Suzawa
  • Kentaroh Miyoshi
  • Hiromasa Yamamoto
  • Mikio Okazaki
  • Seiichiro Sugimoto
  • Masaomi Yamane
  • Shinichi Toyooka
  • 全て表示

52
11
開始ページ
1540
終了ページ
1550
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s00595-022-02492-w

OBJECTIVES: We herein review the outcomes of paediatric lung transplantation (LTx) and analyse subgroups divided by age. METHODS: We retrospectively reviewed 43 consecutive paediatric LTx recipients (< 18 years old: cadaveric LTx [n = 9], living-donor lobar LTx [n = 34]). We also analysed subgroups of patients 1-6 years old (n = 10) and 7-17 years old (n = 33). RESULTS: The 1-, 5- and 10-year overall survival (OS) rates in paediatric recipients were 93%, 82% and 67%, respectively. The 1-, 5- and 10-year graft dysfunction (GD)-free survival rates in paediatric recipients were 85%, 59% and 31%, respectively. The 1- and 5-year OS in the 1- to 6-year-old vs. 7- to 17-year-old groups were 70% vs. 100% and 48% vs. 93%, respectively (p < 0.0001). The 1- and 5-year GD-free survival rates in the 1- to 6-year-old vs. 7- to 17-year-old groups were 60% vs. 93% and 24% vs. 69%, respectively (p = 0.024). The 1- to 6-year-old group showed higher rates of non-standard LTx (p = 0.0001), interstitial pneumonia (p = 0.004) and ventilator dependency (p = 0.007) than the 7- to 17-year-old group. CONCLUSION: Paediatric recipients under 7 years old seemed to have a higher risk of mortality and GD than those 7 years old and older.

リンク情報
DOI
https://doi.org/10.1007/s00595-022-02492-w
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/35357572
ID情報
  • DOI : 10.1007/s00595-022-02492-w
  • PubMed ID : 35357572

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