論文

査読有り 本文へのリンクあり
2017年2月13日

Pitfalls of invasive blood pressure monitoring using the caudal ventral artery in rats

Scientific Reports
  • Hiroki Ohta
  • ,
  • Takao Ohki
  • ,
  • Yuji Kanaoka
  • ,
  • Makoto Koizumi
  • ,
  • Hirotaka J. Okano

7
開始ページ
41907
終了ページ
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/srep41907
出版者・発行元
NATURE PUBLISHING GROUP

© The Author(s) 2017. During rodent experiments, the caudal ventral artery (CVA) is useful for blood pressure (BP) measurement. However, CVA measurements may not reflect the true BP. This study was performed to verify the site-specific accuracy of invasive arterial BP monitoring during surgery in rats. Invasive arterial BP was simultaneously measured in rats via the CVA and the common carotid artery (CCA). The BP values were analysed while the rats were subjected to cooling of the head or tail. Additionally, the rats underwent digital subtraction angiography and histological examination of these arteries. The pressure difference was more significant in the tail cooling group than in the head cooling group. Digital subtraction angiography revealed that angiospasms occurred more frequently in the CVA than in the CCA upon cooling. This phenomenon was supported by histological analysis, which showed that the tunica media area was significantly larger in the CVA than in the CCA. CVA pressure is susceptible to environmental changes and may not accurately reflect the true BP without a strictly controlled laboratory environment. Therefore, understanding the pitfalls of this method is necessary to avoid cooling of the tail during BP measurement.

Web of Science ® 被引用回数 : 1

リンク情報
DOI
https://doi.org/10.1038/srep41907
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28198822
Scopus
https://www.scopus.com/record/display.uri?eid=2-s2.0-85012289376&origin=inward
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000393802300001&DestApp=WOS_CPL
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85012289376&origin=inward 本文へのリンクあり
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85012289376&origin=inward

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