In one-cell-frequency-reuse Orthogonal Frequency Division Multiple Access based Time Division Multiple Access (OF/TDMA) systems, communication is blocked by interference from adjacent cells. The most promising solution would be an adaptive modulation and coding scheme that is controlled by estimating the signal-to-interference ratio (SIR). However, there has so far been no way to accurately estimate the SIR using the spreading codes for OF/TDMA systems, because of the asynchronous fast Fourier transform (FFT). In this paper, we propose a novel SIR estimation method that uses a spread pulse-wave symbol and carrier interferometry. Moreover, to introduce multi- input multi-output systems, we modify the proposed method by allocating a different spreading code to each cell. Computer simulation confirmed that the SIR is estimated accurately even if the FFT is asynchronous. On cell boundaries, the average estimation errors that are a ratio between accurate and estimated propagation characteristics are less than 2 dB.