Hiroshi Kimura

J-GLOBAL         Last updated: Nov 1, 2019 at 21:37
 
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Name
Hiroshi Kimura
E-mail
hkimurabio.titech.ac.jp
URL
http://kimura-lab.bio.titech.ac.jp/
Affiliation
Tokyo Institute of Technology
Section
Cell Biology Center, Institute of Innovative Research
Job title
Professor
Degree
PhD(Hokkaido University)
Research funding number
30241392
Twitter ID
Cell_Tokyo_Tech
ORCID ID
0000-0003-0854-083X

Research Areas

 
 

Education

 
Apr 1987
 - 
Oct 1991
Department of Chemistry II, Graduate School of Science, Hokkaido University
 
Apr 1984
 - 
Mar 1987
Department of Chemistry II, Faculty of Science, Hokkaido University
 

Awards & Honors

 
Aug 2015
Robert Feulgen Prize, The Society for Histochemisty
 

Published Papers

 
Ohka F, Shinjo K, Deguchi S, Matsui Y, Okuno Y, Katsushima K, Suzuki M, Kato A, Ogiso N, Yamamichi A, Aoki K, Suzuki H, Sato S, Arul Rayan N, Prabhakar S, Göke J, Shimamura T, Maruyama R, Takahashi S, Suzumura A, Kimura H, Wakabayashi T, Zong H, Natsume A, Kondo Y
Cancer research   79(19) 4814-4827   Oct 2019   [Refereed]
Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska EA, Peyronnet R, Seyfferth J, Chen HR, de Leeuw R, Herquel B, Kimura H, Mittler G, Kohl P, Medalia O, Korbel JO, Akhtar A
Nature cell biology   21(10) 1248-1260   Oct 2019   [Refereed]
Suda K, Muraoka Y, Ortega-Yáñez A, Yoshida H, Kizu F, Hochin T, Kimura H, Yamaguchi M
Experimental cell research   111673   Oct 2019   [Refereed]
Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew TL, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Kimura H
Development (Cambridge, England)   146(19)    Sep 2019   [Refereed]
Horikoshi N, Kujirai T, Sato K, Kimura H, Kurumizaka H
Biochemical and biophysical research communications   515(4) 719-724   Aug 2019   [Refereed]
Zhao N, Kamijo K, Fox PD, Oda H, Morisaki T, Sato Y, Kimura H, Stasevich TJ
Nature communications   10(1) 2947   Jul 2019   [Refereed]
Chung CI, Sato Y, Ohmuro-Matsuyama Y, Machida S, Kurumizaka H, Kimura H, Ueda H
Scientific reports   9(1) 10188   Jul 2019   [Refereed]
Yamauchi S, Kobashigawa Y, Fukuda N, Teramoto M, Toyota Y, Liu C, Ikeguchi Y, Sato T, Sato Y, Kimura H, Masuda T, Ohtsuki S, Noi K, Ogura T, Morioka H
Molecules (Basel, Switzerland)   24(14)    Jul 2019   [Refereed]
Hayashi-Takanaka Y, Kina Y, Nakamura F, Yamazaki S, Harata M, Soest RWMV, Kimura H, Nakao Y
Scientific reports   9(1) 7540   May 2019   [Refereed]
Nagashima R, Hibino K, Ashwin SS, Babokhov M, Fujishiro S, Imai R, Nozaki T, Tamura S, Tani T, Kimura H, Shribak M, Kanemaki MT, Sasai M, Maeshima K
The Journal of cell biology   218(5) 1511-1530   Mar 2019   [Refereed]
Yamagata K, Nagai K, Miyamoto H, Anzai M, Kato H, Miyamoto K, Kurosaka S, Azuma R, Kolodeznikov II, Protopopov AV, Plotnikov VV, Kobayashi H, Kawahara-Miki R, Kono T, Uchida M, Shibata Y, Handa T, Kimura H, Hosoi Y, Mitani T, Matsumoto K, Iritani A
Scientific reports   9(1) 4050   Mar 2019   [Refereed]
Harada A, Maehara K, Handa T, Arimura Y, Nogami J, Hayashi-Takanaka Y, Shirahige K, Kurumizaka H, Kimura H, Ohkawa Y
Nature cell biology   21(2) 287-296   Feb 2019   [Refereed]
Matsuda T, Irie T, Katsurabayashi S, Hayashi Y, Nagai T, Hamazaki N, Adefuin AMD, Miura F, Ito T, Kimura H, Shirahige K, Takeda T, Iwasaki K, Imamura T, Nakashima K
Neuron   101(3) 472-485.e7   Feb 2019   [Refereed]
Shimi T, Kimura H
The Journal of cell biology   218(2) 385-386   Feb 2019   [Refereed]
Arimura Y, Tachiwana H, Takagi H, Hori T, Kimura H, Fukagawa T, Kurumizaka H
Nature communications   10(1) 576   Feb 2019   [Refereed]
Murashima A, Shinjo K, Katsushima K, Onuki T, Kondoh Y, Osada H, Kagaya N, Shinya K, Kimura H, Yoshida M, Murakami S, Kondo Y
Journal of biochemistry   166(1) 41-50   Jan 2019   [Refereed]
Okita AK, Zafar F, Su J, Weerasekara D, Kajitani T, Takahashi TS, Kimura H, Murakami Y, Masukata H, Nakagawa T
Communications biology   2 17   2019   [Refereed]
Arimura Y, Ikura M, Fujita R, Noda M, Kobayashi W, Horikoshi N, Sun J, Shi L, Kusakabe M, Harata M, Ohkawa Y, Tashiro S, Kimura H, Ikura T, Kurumizaka H
Nucleic acids research   46(19) 10007-10018   Nov 2018   [Refereed]
Azuma Y, Imai H, Kawaguchi Y, Nakase I, Kimura H, Futaki S
Angewandte Chemie (International ed. in English)   57(39) 12771-12774   Sep 2018   [Refereed]
Higgs MR, Sato K, Reynolds JJ, Begum S, Bayley R, Goula A, Vernet A, Paquin KL, Skalnik DG, Kobayashi W, Takata M, Howlett NG, Kurumizaka H, Kimura H, Stewart GS
Molecular cell   71(1) 25-41.e6   Jul 2018   [Refereed]
Arai E, Miura F, Totoki Y, Yamashita S, Tian Y, Gotoh M, Ojima H, Nakagawa H, Takahashi Y, Nakamura H, Hama N, Kato M, Kimura H, Suzuki Y, Ito T, Shibata T, Kanai Y
Epigenomics   10(7) 955-979   Jul 2018   [Refereed]
Takeuchi A, Iida K, Tsubota T, Hosokawa M, Denawa M, Brown JB, Ninomiya K, Ito M, Kimura H, Abe T, Kiyonari H, Ohno K, Hagiwara M
Cell reports   23(5) 1326-1341   May 2018   [Refereed]
Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith S, Tomimatsu K, Mannion E, Smith A, D'Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA, Narita M
Nature communications   9(1) 1840   May 2018   [Refereed]
Harada A, Maehara K, Ono Y, Taguchi H, Yoshioka K, Kitajima Y, Xie Y, Sato Y, Iwasaki T, Nogami J, Okada S, Komatsu T, Semba Y, Takemoto T, Kimura H, Kurumizaka H, Ohkawa Y
Nature communications   9(1) 1400   Apr 2018   [Refereed]
Abe Y, Fujiwara Y, Takahashi H, Matsumura Y, Sawada T, Jiang S, Nakaki R, Uchida A, Nagao N, Naito M, Kajimura S, Kimura H, Osborne TF, Aburatani H, Kodama T, Inagaki T, Sakai J
Nature communications   9(1) 1566   Apr 2018   [Refereed]
Kuroki S, Nakai Y, Maeda R, Okashita N, Akiyoshi M, Yamaguchi Y, Kitano S, Miyachi H, Nakato R, Ichiyanagi K, Shirahige K, Kimura H, Shinkai Y, Tachibana M
Stem cell reports   10(4) 1340-1354   Apr 2018   [Refereed]
Ruppert JG, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash AA, Ohta S, Earnshaw WC
The EMBO journal   37(6)    Mar 2018   [Refereed]
Chen CCL, Goyal P, Karimi MM, Abildgaard MH, Kimura H, Lorincz MC
Genome research   28(1) 37-51   Jan 2018   [Refereed]
Jenness C, Giunta S, Müller MM, Kimura H, Muir TW, Funabiki H
Proceedings of the National Academy of Sciences of the United States of America   115(5) E876-E885   Jan 2018   [Refereed]
Handoko L, Kaczkowski B, Hon CC, Lizio M, Wakamori M, Matsuda T, Ito T, Jeyamohan P, Sato Y, Sakamoto K, Yokoyama S, Kimura H, Minoda A, Umehara T
Epigenetics   13(4) 410-431   2018   [Refereed]
Sato Y, Stasevich TJ, Kimura H
Methods in molecular biology (Clifton, N.J.)   1861 91-102   2018   [Refereed]
Kajitani T, Kato H, Chikashige Y, Tsutsumi C, Hiraoka Y, Kimura H, Ohkawa Y, Obuse C, Hermand D, Murakami Y
Proceedings of the National Academy of Sciences of the United States of America   114(52) E11208-E11217   Dec 2017   [Refereed]
Imre L, Simándi Z, Horváth A, Fenyőfalvi G, Nánási P, Niaki EF, Hegedüs É, Bacsó Z, Weyemi U, Mauser R, Ausio J, Jeltsch A, Bonner W, Nagy L, Kimura H, Szabó G
Scientific reports   7(1) 12734   Oct 2017   [Refereed]
Shirai A, Kawaguchi T, Shimojo H, Muramatsu D, Ishida-Yonetani M, Nishimura Y, Kimura H, Nakayama JI, Shinkai Y
eLife   6    Sep 2017   [Refereed]
An PNT, Shimaji K, Tanaka R, Yoshida H, Kimura H, Fukusaki E, Yamaguchi M
Scientific reports   7(1) 7343   Aug 2017   [Refereed]
Shirai A, Kawaguchi T, Shimojo H, Muramatsu D, Ishida-Yonetani M, Nishimura Y, Kimura H, Nakayama JI, Shinkai Y
eLife   6    Aug 2017   [Refereed]
Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A
Experimental cell research   357(2) 202-210   Aug 2017   [Refereed]
Isobe SY, Nagao K, Nozaki N, Kimura H, Obuse C
Cell reports   20(2) 297-307   Jul 2017   [Refereed]
Arai R, Sugawara T, Sato Y, Minakuchi Y, Toyoda A, Nabeshima K, Kimura H, Kimura A
Scientific reports   7(1) 3631   Jun 2017   [Refereed]
Kurita K, Sakamoto T, Yagi N, Sakamoto Y, Ito A, Nishino N, Sako K, Yoshida M, Kimura H, Seki M, Matsunaga S
Scientific reports   7 45894   Apr 2017   [Refereed]
Taguchi H, Xie Y, Horikoshi N, Maehara K, Harada A, Nogami J, Sato K, Arimura Y, Osakabe A, Kujirai T, Iwasaki T, Semba Y, Tachibana T, Kimura H, Ohkawa Y, Kurumizaka H
Biochemistry   56(16) 2184-2196   Apr 2017   [Refereed]
Kujirai T, Horikoshi N, Sato K, Maehara K, Machida S, Osakabe A, Kimura H, Ohkawa Y, Kurumizaka H
Nucleic acids research   45(6) 3612   Apr 2017   [Refereed]
Kakumu E, Nakanishi S, Shiratori HM, Kato A, Kobayashi W, Machida S, Yasuda T, Adachi N, Saito N, Ikura T, Kurumizaka H, Kimura H, Yokoi M, Sakai W, Sugasawa K
Genes to cells : devoted to molecular & cellular mechanisms   22(3) 310-327   Mar 2017   [Refereed]
Shishido Y, Baba T, Sato T, Shima Y, Miyabayashi K, Inoue M, Akiyama H, Kimura H, Kanai Y, Ishihara Y, Haraguchi S, Miyazaki A, Rozman D, Yamazaki T, Choi MH, Ohkawa Y, Suyama M, Morohashi KI
Scientific reports   7 41912   Feb 2017   [Refereed]
Shiomi T, Muto A, Hozumi S, Kimura H, Kikuchi Y
Zoological science   34(1) 64-71   Feb 2017   [Refereed]
Ueda J, Harada A, Urahama T, Machida S, Maehara K, Hada M, Makino Y, Nogami J, Horikoshi N, Osakabe A, Taguchi H, Tanaka H, Tachiwana H, Yao T, Yamada M, Iwamoto T, Isotani A, Ikawa M, Tachibana T, Okada Y, Kimura H, Ohkawa Y, Kurumizaka H, Yamagata K
Cell reports   18(3) 593-600   Jan 2017   [Refereed]
Yamazaki T, Hatano Y, Handa T, Kato S, Hoida K, Yamamura R, Fukuyama T, Uematsu T, Kobayashi N, Kimura H, Yamagata K
PloS one   12(5) e0177764   2017   [Refereed]
Partolina M, Thoms HC, MacLeod KG, Rodriguez-Blanco G, Clarke MN, Venkatasubramani AV, Beesoo R, Larionov V, Neergheen-Bhujun VS, Serrels B, Kimura H, Carragher NO, Kagansky A
Cell death discovery   3 16077   2017   [Refereed]
Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, Sato S, Takahashi S, Kimura H, Totoki Y, Shibata T, Naito M, Kim HJ, Miyata K, Kataoka K, Kondo Y
Nature communications   7 13616   Dec 2016   [Refereed]
Muramatsu D, Kimura H, Kotoshiba K, Tachibana M, Shinkai Y
Cell structure and function   41(2) 145-152   Dec 2016   [Refereed]

Misc

 
木村宏
Dojin News   (166) 1‐5   Sep 2018
木村宏
バイオイメージング   27(2) 64   Aug 2018
佐藤 優子, 木村 宏
化學工業   69(8) 589-594   Aug 2018
TASHIRO Satoshi, KIMURA Hiroshi
Seibutsu Butsuri   58(4) 221-222   2018
木村 宏
生体の科学   68(3) 199-203   May 2017
KIMURA Hiroshi, SATO Yuko
Journal of Information Processing and Management   60(8) 555-563   2017
<p>The genetic information of a living organism is encoded on the genomic DNA. To fully understand the phenomenon of life, it is critical to elucidate how genes are expressed as required. In addition to the regulation by transcription factors that...
木村宏, 佐藤優子
遺伝子医学MOOK   (25) 247-253,11   Aug 2013
KIMURA Hiroshi, SATO Yuko, HAYASHI TAKANAKA Yoko
Seibutsu Butsuri   52(5) 234-235   Sep 2012
木村 宏, 林 陽子
医学のあゆみ   235(10) 995-1000   Dec 2010
Kim Jong-Myong, To Taiko Kim, Kawashima Makiko, Morosawa Taeko, Kimura Hiroshi, Shinozaki Kazuo, Seki Motoaki
Plant and Cell Physiology Supplement   2008(0) 465-465   2008
Modulation of histone N-tail modifications correlates with transcriptional activation and repression in eukaryote. In plant, histone modifications are altered in vernalization process. However, no clear correlations between the status of histone m...
木村宏, 竹安邦夫, 米田悦啓
   2004   [Refereed]
木村宏
   2003   [Refereed]
木村宏
   2003   [Refereed]
木村宏
   2002   [Refereed]
木村宏
   2002   [Refereed]

Conference Activities & Talks

 
A chromatin integration labeling method enables epigenomic profiling with lower input
Tetsuya Handa, Akihito Harada, Kazumitsu Maehara, Yasuhiro Arimura, Jumpei Nogami, Yoko Hayashi-Takanaka, Katsuhiko Shirahige, Hitoshi Kurumizaka, Yasuyuki Ohkawa and Hiroshi Kimura
3R&3C Symposium   12 Nov 2018   
Sensing Histone Modification and Transcription Dynamics in Living Cells [Invited]
Hiroshi Kimura
2nd Epigenetics and Bioengineering Conference   6 Oct 2018   
Chromatin Modification Dynamics in Living Cells [Invited]
Hiroshi Kimura
Gordon Research Conference "Chromatin Structure and Function"   22 Jul 2018   
Chromatin modification dynamics [Invited]
Hiroshi Kimura
Joint Annual Meeting of JSDB 51st and JSCB 70th   5 Jun 2018   
Chromatin modification dynamics during gene activation and inactivation in living cells [Invited]
Hiroshi Kimura
CSHL Meeting "Nuclear Organization & Function"   1 May 2018   
木村宏
日本蛋白質科学会年会プログラム・要旨集   26 May 2014   
上運天太一, 島田明美, 出野尚, 中村芳樹, 木村宏, 立花誠, 中島和久, 二藤彰
日本骨代謝学会学術集会プログラム抄録集   2014   
佐藤優子, 木村宏
がん研究分野の特性等を踏まえた支援活動公開シンポジウムプログラム・抄録集 平成25年度   2014   
木村宏
金沢大学がん進展制御研究所がんの転移・薬剤耐性に関わる先導的研究拠点   2014   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2007 - 2009    Investigator(s): Hiroshi KIMURA
To understand the structure and dynamics of specialized chromatin harboring distinct histone modifications, we employed chromatin immunoprecipitation followed by mass spectrometry analysis and live cell imaging by using modification-specific monoc...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(特定領域研究)
Project Year: 2004 - 2008    Investigator(s): Hiroshi KIMURA
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2003 - 2005    Investigator(s): Hiroshi KIMURA
In eukaryotic nuclei, DNA is wrapped around an octamer containing two copies of core histones, H2A, H2B, H3, and H4, making nucleosomes, the fundamental units of chromatin. Lines of evidence indicate that nucleosomes in living cells are not static...