Tomomi Hishinuma

Profile Information

Affiliation: Juntendo University

Degree: 医学博士(順天堂大学)

J-GLOBAL ID: 201801014839642945
researchmap Member ID: B000316265

Research Interests

Research Areas

Life sciences / Bacteriology /

Papers

Klebsiella pneumoniae co-harbouring bla NDM-1 , armA and mcr-10 isolated from blood samples in Myanmar.

Tatsuya Tada, Satoshi Oshiro, Shin Watanabe, Mari Tohya, Tomomi Hishinuma, Thi Thi Htoon, Htay Htay Tin, Teruo Kirikae

Journal of medical microbiology, 72(9), Sep, 2023
Emergence of colistin-resistant Acinetobacter modestus harbouring the intrinsic phosphoethanolamine transferase EptA.

Masafumi Sakuma, Masahito Hashimoto, Kanako Nishi, Mari Tohya, Tomomi Hishinuma, Masahiro Shimojima, Tatsuya Tada, Teruo Kirikae

Journal of global antimicrobial resistance, 33 101-108, Mar 9, 2023
Emergence of carbapenem-resistant Pseudomonas alcaligenes and Pseudomonas paralcaligenes clinical isolates with plasmids harbouring bla IMP-1 in Japan.

Emi Ono, Mari Tohya, Tatsuya Tada, Tomomi Hishinuma, Shin Watanabe, Kyoko Kuwahara-Arai, Teruo Kirikae

Journal of medical microbiology, 72(3), Mar, 2023
Correction for Tohya et al., "Whole-Genome Sequencing-Based Re-Identification of Pseudomonas putida/fluorescens Clinical Isolates Identified by Biochemical Bacterial Identification Systems".

Mari Tohya, Kanae Teramoto, Shin Watanabe, Tomomi Hishinuma, Masahito Shimojima, Miho Ogawa, Tatsuya Tada, Yoko Tabe, Teruo Kirikae

Microbiology spectrum, 11(2) e0430522, Feb 21, 2023
CID12261165, a flavonoid compound as antibacterial agents against quinolone-resistant Staphylococcus aureus.

Yuh Morimoto, Yoshifumi Aiba, Kazuhiko Miyanaga, Tomomi Hishinuma, Longzhu Cui, Tadashi Baba, Keiichi Hiramatsu

Scientific reports, 13(1) 1725-1725, Jan 31, 2023
Modified Drug-Susceptibility Testing and Screening Culture Agar for Colistin-Susceptible Enterobacteriaceae Isolates Harboring a Mobilized Colistin Resistance Gene mcr-9.

Pegah Kananizadeh, Tatsuya Tada, Satoshi Oshiro, Tomomi Hishinuma, Mari Tohya, Yuki Uehara, Yumi Kumagai, Isao Nagaoka, Kanako Nishi, Masahito Hashimoto …

Journal of clinical microbiology, 60(12) e0139922, Dec 21, 2022
Plasmids Harboring a Tandem Duplicate of bla_VIM-24 in Carbapenem-Resistant ST1816 Pseudomonas aeruginosa in Japan

Tomomi Hishinuma, Tatsuya Tada, Mari Tohya, Masaki Shintani, Masato Suzuki, Masahiro Shimojima, Teruo Kirikae

Microbial Drug Resistance, Nov 15, 2022
Stenotrophomonas maltophilia from Nepal Producing Two Novel Antibiotic Inactivating Enzymes, a Class A β-Lactamase KBL-1 and an Aminoglycoside 6'-N-Acetyltransferase AAC(6')-Iap.

Ryota Kawauchi, Tatsuya Tada, Jatan B Sherchan, Shovita Shrestha, Mari Tohya, Tomomi Hishinuma, Teruo Kirikae, Jeevan B Sherchand

Microbiology spectrum, 10(4) e0114322, Jul 7, 2022
Whole-Genome Sequencing-Based Re-Identification of Pseudomonas putida/fluorescens Clinical Isolates Identified by Biochemical Bacterial Identification Systems.

Mari Tohya, Kanae Teramoto, Shin Watanabe, Tomomi Hishinuma, Masahito Shimojima, Miho Ogawa, Tatsuya Tada, Yoko Tabe, Teruo Kirikae

Microbiology spectrum, 10(2) e0249121, Apr 27, 2022
Emergence of a highly colistin-resistant Aeromonas jandaei clinical isolate harbouring four genes encoding phosphoethanolamine transferases in Nepal.

Tomoki Komeda, Shovita Shrestha, Jatan B Sherchan, Mari Tohya, Tomomi Hishinuma, Jeevan B Sherchand, Tatsuya Tada, Teruo Kirikae

International journal of antimicrobial agents, 59(4) 106544-106544, Apr, 2022
Molecular characterisation of carbapenem-resistant Pseudomonas aeruginosa clinical isolates in Nepal.

Toshihiro Takahashi, Tatsuya Tada, Shovita Shrestha, Tomomi Hishinuma, Jatan B Sherchan, Mari Tohya, Teruo Kirikae, Jeevan B Sherchand

Journal of global antimicrobial resistance, 26 279-284, Sep, 2021
Three novel species of the Bacillus cereus group isolated from clinical samples in Japan.

Mari Tohya, Tomomi Hishinuma, Shin Watanabe, Masahito Shimojima, Miho Ogawa, Tatsuya Tada, Teruo Kirikae

International journal of systematic and evolutionary microbiology, 71(9), Sep, 2021
Development of an immunochromatographic kit to detect severe acute respiratory syndrome coronavirus 2.

Satoshi Oshiro, Yoko Tabe, Keiji Funatogawa, Kaori Saito, Tatsuya Tada, Tomomi Hishinuma, Naeko Mizutani, Makoto Akiwa, Jun-Ichiro Sekiguchi, Takashi Miida …

Journal of virological methods, 294 114183-114183, Aug, 2021
Emergence of clinical isolates of Pseudomonas asiatica and Pseudomonas monteilii from Japan harbouring an acquired gene encoding a carbapenemase VIM-2.

Mari Tohya, Kohei Uechi, Tatsuya Tada, Tomomi Hishinuma, Takeshi Kinjo, Takeya Ohshiro, Shiro Maeda, Teruo Kirikae, Jiro Fujita

Journal of medical microbiology, 70(1), Jan, 2021
Emergence and spread of VIM-type metallo-β-lactamase-producing Pseudomonas aeruginosa clinical isolates in Japan.

Tomomi Hishinuma, Hiroki Uchida, Mari Tohya, Masahiro Shimojima, Tatsuya Tada, Teruo Kirikae

Journal of global antimicrobial resistance, 23 265-268, Dec, 2020
Emergence of Carbapenem-Resistant Providencia rettgeri and Providencia stuartii Producing IMP-Type Metallo-β-Lactamase in Japan.

Shu Iwata, Tatsuya Tada, Tomomi Hishinuma, Mari Tohya, Satoshi Oshiro, Kyoko Kuwahara-Arai, Miho Ogawa, Masahiro Shimojima, Teruo Kirikae

Antimicrobial agents and chemotherapy, 64(11), Oct 20, 2020
RNA Sequencing Identifies a Common Physiology in Vancomycin- and Ciprofloxacin-Tolerant Staphylococcus aureus Induced by ileS Mutations.

Madhuri Singh, Miki Matsuo, Takashi Sasaki, Tomomi Hishinuma, Norio Yamamoto, Yuh Morimoto, Teruo Kirikae, Keiichi Hiramatsu

Antimicrobial agents and chemotherapy, 64(10), Sep 21, 2020
Molecular epidemiology of multidrug-resistant Acinetobacter baumannii isolates from hospitals in Myanmar.

Tatsuya Tada, Hiroki Uchida, Tomomi Hishinuma, Shin Watanabe, Mari Tohya, Kyoko Kuwahara-Arai, San Mya, Khin Nyein Zan, Teruo Kirikae, Htay Htay Tin

Journal of global antimicrobial resistance, 22 122-125, Sep, 2020
Pseudomonas izuensis sp. nov., a novel species isolated from Izu Oshima, Japan.

Yu Jie Lu, Yuh Morimoto, Mari Tohya, Tomomi Hishinuma, Keiichi Hiramatsu, Teruo Kirikae, Tadashi Baba

International journal of systematic and evolutionary microbiology, 70(7) 4212-4216, Jul, 2020
Highly multidrug-resistant Morganella morganii clinical isolates from Nepal co-producing NDM-type metallo-β-lactamases and the 16S rRNA methylase ArmA.

Shovita Shrestha, Tatsuya Tada, Jatan B Sherchan, Hiroki Uchida, Tomomi Hishinuma, Satoshi Oshiro, Shinichiro Morioka, Hari Kattel, Teruo Kirikae, Jeevan B Sherchand

Journal of medical microbiology, 69(4) 572-575, Apr, 2020

Misc.

ミャンマーの医療施設で分離された多剤耐性緑膿菌の分子疫学解析(Molecular epidemiology of multidrug-resistant Pseudomonas aeruginosa clinical isolates in Myanmar)

多田達哉, 内田大貴, 菱沼知美, Mya San, Tin Htay Htay, 切替照雄

日本細菌学雑誌, 74(1) 128-128, Mar, 2019
日本の医療施設で分離されたGES‐5カルバペネマーゼ産生MDRPの分子疫学解析

菱沼知美, 多田達哉, 島田佳世, 霜島正浩, 切替照雄

緑膿菌感染症研究会講演記録, 52nd 79‐81-81, Oct, 2018
黄色ブドウ球菌のキノロン系薬トレランス株の解析

平松未悠, 菱沼知美, 森本ゆふ, 平松啓一, 佐々木崇

日本化学療法学会雑誌, 64(Suppl.A) 182-182, May, 2016
バンコマイシン中間耐性MRSA(VISA)の耐性機構と復帰抗生物質

平松啓一, 森本ゆふ, 馬場理, 佐々木崇, 菱沼知美, 片山由紀, 松尾美記, 桑原京子, 上原由紀, 五十嵐雅之

日本化学療法学会雑誌, 64(3) 503-512, May, 2016
難治性MRSA感染症の再燃に関与しているslow-VISA(バンコマイシン中間耐性黄色ブドウ球菌)について

片山由紀, 菱沼知美, 松尾美記, 相羽由詞, 平松啓一, 佐々木崇, 関根美和

日本化学療法学会雑誌, 64(3) 591-591, May, 2016
MRSA反復感染と関連があると考えられる'slow-VISA'におけるバンコマイシン耐性メカニズム(The Mechanism of Resistance to Vancomycin in 'slow-VISA Possibly Responsible for Recurrent MRSA Infection)

片山由紀, 相羽由詞, 関根美和, 松尾美記, 菱沼知美, 平松啓一

日本化学療法学会雑誌, 64(Suppl.A) 181-181, May, 2016
薬剤耐性の基礎研究難治性MRSA感染症の再燃に寄与するslow-VISAのバンコマイシン耐性化機構について(Basic Researches in Bacterial Drug Resistances Mechanism of Resistance to Vancomycin in 'slow-VISA Responsible for a Recurrent MRSA Infection)

片山由紀, 相羽由詞, 関根美和, 松尾美記, 菱沼知美, 平松啓一

日本細菌学雑誌, 71(1) 48-48, Feb, 2016
RNAポリメラーゼβ'サブユニット(RpoC)の変異はヘテロ中間耐性黄色ブドウ球菌(hVISA)を"slow VISA"に変換する

松尾美記, 菱沼知美, 片山由紀, 平松啓一

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回 [2P1202]-[2P1202], Dec, 2015
Staphylococcus aureusにおいてバンコマイシン抵抗性を持つslow VISA表現型の特徴(Characterization of slow VISA Phenotype of Vancomycin Resistance in Staphylococcus aureus)

片山由紀, 菱沼知美, 岩本昭, 相羽由詞, 佐々木崇, 松尾美記, 平松啓一

日本化学療法学会雑誌, 63(Suppl.A) 171-171, May, 2015
新規バンコマイシン耐性の表現型であるslow-VISAの耐性化機構について(Characterization of slow VISA , A Novel Phenotype of Vancomycin Resistance in Staphylococcus aureus)

片山由紀, 菱沼知美, 岩本昭, 相羽由詞, 佐々木崇, 松尾美記, 平松啓一

日本細菌学雑誌, 70(1) 194-194, Feb, 2015
rpoC変異を有するhVISAにおけるバンコマイシン耐性の獲得と損失(Acquisition and loss of vancomycin resistance in hVISA with rpoC mutaion)

松尾美記, 菱沼知美, 片山由紀, 平松啓一

日本細菌学雑誌, 70(1) 195-195, Feb, 2015
黄色ブドウ球菌のrpoB変異による種々の薬剤感受性への影響

相羽由詞, 片山由紀, 菱沼知美, 佐々木崇, 桑原京子, 平松啓一

日本細菌学雑誌, 70(1) 195-195, Feb, 2015
なぜ難治性MRSA感染症は再燃するのか

片山由紀, 菱沼知美, 松尾美記, 相羽由詞, 佐々木崇, 関根美和, 平松啓一

Pharmaco-Hematologyシンポジウム講演要旨集, 16th, 2015
難治性MRSA感染症の克服

片山由紀, 菱沼知美, 松尾美記, 相羽由詞, 佐々木崇, 関根美和, 平松啓一

日本ブドウ球菌研究会プログラム・講演要旨集, 60th, 2015
hVISA株のMu3系統に由来するVISAの表現型の新分類である「低速増殖VISA(slow VISA)」の特性分析(Characterization of a novel class of VISA phenotype 'slow VISA' derived from hVISA strain Mu3)

片山由紀, 齋藤充恵, 菱沼知美, 岩本昭, 平松啓一

日本細菌学雑誌, 69(1) 197-197, Feb, 2014
rpoB遺伝子の単一アミノ酸置換は、Mu3株のhVISA低速増殖VISA(slow VISA)への転換を促進する(A single amino-acid substitution of rpoB gene promotes conversion of hVISA-to-slow VISA in Mu3)

齋藤充恵, 片山由紀, 菱沼知美, 桑原京子, 相羽由詞, 平松啓一

日本細菌学雑誌, 69(1) 197-197, Feb, 2014
Staphylococcus aureus株におけるバンコマイシン中等度耐性の完全再構成(Complete reconstitution of vancomycin-intermediate resistance in a Staphylococcus aureus strain)

片山由紀, 菱沼知美, 松尾美記, 平松啓一

日本細菌学雑誌, 67(1) 137-137, Feb, 2012
Staphylococcus aureusにおいてrpoB遺伝子変異はβラクタム系抗生物質耐性に関与する(A mutation of rpoB gene contributes to β-lactam antibiotic resistance in Staphylococcus aureus)

相羽由詞, 片山由紀, 菱沼知美, 崔龍洙, 平松啓一

日本細菌学雑誌, 67(1) 138-138, Feb, 2012
毒素遺伝子の転写産物と翻訳産物によるメチシリン耐性黄色ブドウ球菌の病原性制御

垣内力, 齋藤祐樹, 長野源太郎, 幾尾真理子, 大前陽輔, 花田雄一, 韓笑, 桑原京子, 菱沼知美, 馬場理 …

生体膜と薬物の相互作用シンポジウム講演要旨集, 32nd 53-54, Nov 29, 2010
種々の抗生物質暴露によるhVISA(Heterogeneous Vancomycin-Intermediate Staphylococcus.aureus)の出現

片山由紀, 渡辺由季子, 松尾美記, 菱沼知美, 平松啓一, 山川潤

日本化学療法学会雑誌, 58(Suppl.A) 266-266, Apr, 2010

Research Projects

日本の多剤耐性緑膿菌が産生するカルバペネマーゼの進化様式の解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2020 - Mar, 2023

菱沼知美

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