hitoshi okazawa

J-GLOBAL         Last updated: Apr 8, 2019 at 11:07
 
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Name
hitoshi okazawa
Affiliation
Tokyo Medical and Dental University
Section
Neuropathology
Job title
Professor and Chairman
Degree
M.D., Ph.D.

Profile

Neurologist and Neuroscientist. 1984: MD, graduated from The University of Tokyo, School of Medicine. After becoming the staff member of Department of Neurology, The University of Tokyo, got PhD degree in 1991 by discovery of Oct-3/4:Oct-4:Oct-3 (Okazawa et al., Cell1990; EMBO J 1991), which is now well known as a key regulator of ES cell and the most important factor for generating iPS cell. After working at Max-Planck Institute for Psychiatry as a staff scientist, assigned to assistant professor (Department of Neurology, The University of Tokyo) and started the research of neurodegenerative diseases, and discovered polyglutamine binding protein-1 in polyglutamine disease pathology (PQBP1) (Hum Mol Genet 1999; Neuron 2002), and intracellular accumulation of amyloid beta and JNK activation in Alzheimer's disease pathology (Mol Brain Res 2000). Expanded the research also to mental retardation and microcephaly after discovery of PQBP1. 2001: Head, Tokyo Metropolitan Institute for Neuroscience, 2003: Professor and Chairman, Neuropathology, Tokyo Medical and Dental University. 2014: Director, Center for Brain Integration Research, Tokyo Medical and Dental University.

Awards & Honors

 
May 2011
Narabayashi Prize, Japanese Society of Neurology
 

Published Papers

 
Rahman SK, Okazawa H, Chen YW
Journal of structural biology      Apr 2019   [Refereed]
Bannai T, Mano T, Chen X, Ohtomo G, Ohtomo R, Tsuchida T, Koshi-Mano K, Hashimoto T, Okazawa H, Iwatsubo T, Tsuji S, Toda T, Iwata A
Scientific reports   9(1) 2827   Feb 2019   [Refereed]
Inoue S, Hayashi K, Fujita K, Tagawa K, Okazawa H, Kubo KI, Nakajima K
The Journal of neuroscience : the official journal of the Society for Neuroscience   39(4) 678-691   Jan 2019   [Refereed]
Chen X, Kondo K, Okazawa H
Methods in molecular biology (Clifton, N.J.)   1880 529-534   2019   [Refereed]
Tanaka H, Kondo K, Chen X, Homma H, Tagawa K, Kerever A, Aoki S, Saito T, Saido T, Muramatsu SI, Fujita K, Okazawa H
Molecular psychiatry      Oct 2018   [Refereed]
Furotani K, Kamimura K, Yajima T, Nakayama M, Enomoto R, Tamura T, Okazawa H, Sone M
PloS one   13(9) e0204048   2018   [Refereed]
Fujita K, Homma H, Kondo K, Ikuno M, Yamakado H, Tagawa K, Murayama S, Takahashi R, Okazawa H
eNeuro   5(4)    Jul 2018   [Refereed]
Okazawa H
ACS chemical neuroscience      Mar 2018   [Refereed]
Kawahori K, Hashimoto K, Yuan X, Tsujimoto K, Hanzawa N, Hamaguchi M, Kase S, Fujita K, Tagawa K, Okazawa H, Nakajima Y, Shibusawa N, Yamada M, Ogawa Y
Thyroid : official journal of the American Thyroid Association      Feb 2018   [Refereed]
Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, Imoto S, Akatsu H, Hashizume Y, Kaibuchi K, Miyano S, Okazawa H
Nature communications   9(1) 433   Jan 2018   [Refereed]
Irie R, Kamagata K, Kerever A, Ueda R, Yokosawa S, Otake Y, Ochi H, Yoshizawa H, Hayashi A, Tagawa K, Okazawa H, Takahashi K, Sato K, Hori M, Arikawa-Hirasawa E, Aoki S
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine      Dec 2017   [Refereed]
Fujita K, Mao Y, Uchida S, Chen X, Shiwaku H, Tamura T, Ito H, Watase K, Homma H, Tagawa K, Sudol M, Okazawa H
Nature communications   8(1) 1864   Nov 2017   [Refereed]
Sato K, Kerever A, Kamagata K, Tsuruta K, Irie R, Tagawa K, Okazawa H, Arikawa-Hirasawa E, Nitta N, Aoki I, Aoki S
Acta radiologica open   6(4) 2058460117703816   Apr 2017   [Refereed]
Yamanishi E, Hasegawa K, Fujita K, Ichinose S, Yagishita S, Murata M, Tagawa K, Akashi T, Eishi Y, Okazawa H
Acta neuropathologica communications   5(1) 19   Mar 2017   [Refereed]
Okazawa H
Proceedings of the Japan Academy. Series B, Physical and biological sciences   93(6) 361-377   2017   [Refereed]
Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, Kaye J, Finkbeiner S, Okazawa H
Scientific reports   6 33861   Sep 2016   [Refereed]
Mao Y, Chen X, Xu M, Fujita K, Motoki K, Sasabe T, Homma H, Murata M, Tagawa K, Tamura T, Kaye J, Finkbeiner S, Blandino G, Sudol M, Okazawa H
Human molecular genetics      Sep 2016   [Refereed]
Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, Homma H, Tamura T, Watanabe H, Katsuno M, Matsumi C, Kajikawa M, Saito T, Saido T, Sobue G, Miyawaki A, Okazawa H
Scientific reports   6 31895   Aug 2016   [Refereed]
Taniguchi JB, Kondo K, Fujita K, Chen X, Homma H, Sudo T, Mao Y, Watase K, Tanaka T, Tagawa K, Tamura T, Muramatsu SI, Okazawa H
Human molecular genetics      Aug 2016   [Refereed]