論文

査読有り 国際誌
2019年2月18日

Hepatic hypertrophy and hemodynamics of portal venous flow after percutaneous transhepatic portal embolization.

BMC surgery
  • Shingo Shimada
  • ,
  • Toshiya Kamiyama
  • ,
  • Hideki Yokoo
  • ,
  • Tatsuya Orimo
  • ,
  • Kenji Wakayama
  • ,
  • Akihisa Nagatsu
  • ,
  • Tatsuhiko Kakisaka
  • ,
  • Hirofumi Kamachi
  • ,
  • Daisuke Abo
  • ,
  • Yusuke Sakuhara
  • ,
  • Akinobu Taketomi

19
1
開始ページ
23
終了ページ
23
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1186/s12893-019-0486-8

BACKGROUND: Percutaneous transhepatic portal embolization (PTPE) is useful for safe major hepatectomy. This study investigated the correlation between hepatic hypertrophy and hemodynamics of portal venous flow by ultrasound sonography after PTPE. METHODS: We analyzed 58 patients with PTPE, excluding those who underwent recanalization (n = 10). Using CT volumetry results 2 weeks after PTPE, the patients were stratified into a considerable hypertrophy group (CH; n = 15) with an increase rate of remnant liver volume (IR-RLV) ≥ 40% and a minimal hypertrophy group (MH; n = 33) with an IR-RLV < 40%. We investigated the hemodynamics of portal venous flow after PTPE and the favorable factors for hepatic hypertrophy. RESULTS: Univariate and multivariate analysis identified the indocyanine green retention rate at 15 min (ICGR15) and increase rate of portal venous flow volume (IR-pFV) at the non-embolized lobe on day 3 after PTPE as independent favorable factors of IR-RLV. Patients with IR-pFV on day 3 after PTPE ≥100% and ICGR15 ≤ 15% (n = 13) exhibited significantly increased IR-RLV compared with others (n = 35). CONCLUSIONS: Cases with high IR-pFV on day 3 after PTPE exhibited better hepatic hypertrophy. Preserved liver function and increased portal venous flow on day 3 were important.

リンク情報
DOI
https://doi.org/10.1186/s12893-019-0486-8
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30777042
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379972

エクスポート
BibTeX RIS