MANO Hiroshi

J-GLOBAL         Last updated: Nov 25, 2019 at 14:03
 
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Name
MANO Hiroshi
Affiliation
Josai University
Section
Faculty of Pharmaceutical Sciences, Department of Clinical Dietetics and Human Nutrition, Laboratay of Food Science
Job title
Associate Professor
Degree
(BLANK)
Research funding number
20265359

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
2001
   
 
- Josai University, Faculty of Pharmacutical Sciences
 
1998
 - 
2001
Tokyo University of Agriculture
 
1994
 - 
1998
Meikai University
 

Education

 
 
 - 
1994
Graduate School, Division of Agriculture, Tokyo University of Agriculture
 
 
 - 
1989
Faculty of Agriculture, Tokyo University of Agriculture
 

Published Papers

 
1. The effects of collagen peptide supplementation -A double-blind, placebo-controlled, randomized trial in healthy university students belonging to a running club-
Yoshifumi Kimira, Masafumi Saito, Seiji Kushibe, Kaho Nmomura, Yoshihiro Osawa, Yusuke Sekiguchi,Jun Shimizu, Sachie Nakatani, Seiko Koizumi, Naoki Inoue, Yoshihisa Mori, Jun Kobayashi, Hiroshi Mano
Jpn. Pharmacol. Ther.   47(9) 1455-1462   2019   [Refereed]
Collagen-derived dipeptide prolyl hydroxyproline directly binds to Foxg1 to change its conformation and inhibit the interaction with Runx2.
Nomura Kaho, Yoshifumi Kimira, Yoshihiro Osawa Y1, Jun Shimizu, Aya Kataoka-Matsushita, Hiroshi Mano
Biosci. Biotechnol. Biochem.   83(11) 2027-2033   2019   [Refereed]
Collagen-derived dipeptide prolyl-hydroxyproline promotes osteogenic differentiation through Foxg1.
Yoshifumi Kimira, Haruka Odaira, Kaho Nomura, Yuri Taniuchi, Naoki Inoue, Sachie Nakatani, Jun Shimizu, Masahiro Wada, Hiroshi Mano
Cell. Mol. Biol. Lett.   22(27) doi: 10.1186/s11658-017-0060-2   Dec 2017   [Refereed]
Takahiro Yoshizaki, Yoshifumi Kimira, Hiroshi Mano, Masako Ota, Ken Iwatsuki, Yuichi Oishi, Takumi Yamane
J Nutr. Sci. Vitaminol   62 15-20   2017   [Refereed]
Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation.
YUUSUKE SEKIGUCHI, HIROSHI MANO, SACHIE NAKATANI, JUN SHIMIZU, AYA KATAOKA, KANA OGURA, YOSHIFUMI KIMIRA, MIDORI EBATA and MASAHIRO WADA
MOLECULAR MEDICINE REPORTS   doi: 10.3892/mmr.2017.6752(2) 1328-1332   Jun 2017   [Refereed]
Takahiro SHIGA, Yoshifumi KIMIRA, Hiroshi MANO, Tetsunori KAWATA, Tadahiro TADOKORO, Tsukasa SUZUKI, Yuji YAMAMOTO
Bioscience, Biotechnology, and Biochemistry   80 510-513   2016   [Refereed]
Hironobu Asai, Sachie Nakatani, Takuya Kato, Tatsuo Shimizu, Hiroshi Mano, Kenji Kobata, and Masahiro Wada
Biol. Pharm. Bull.   39 1035-1041   2016   [Refereed]
iroshi Mano, Sachie Nakatani, Yoshifumi Kimira, Mikiko Mano, Yuusuke Sekiguchi,Ryang-Hyock Ima, Jun Shimizu, Masahiro Wada
Bioscience, Biotechnology, and Biochemistry   10.1080/09168451.2015.1008976    2015   [Refereed]
Jun Shimizu, Naoto Asami, Aya Kataoka, Fumihito Sugihara, Naoki Inoue, Yoshifumi Kimira, Masahiro Wada, Hiroshi Mano
Biochem. Biophys. Res. Commun.   456 626-630   2015   [Refereed]
Yoshifumi Kimira, Kana Ogura, Yuri Taniuchi, Aya Kataoka, Naoki Inoue, Fumihito Sugihara, Sachie Nakatani, Jun Shimizu, Masahiro Wada, Hiroshi Mano
Biochem. Biophys. Res. Commun.   453 498-501   2015   [Refereed]
Functional Food on Bone and Cartilage
KIMIRA Yoshifumi and MANO Hiroshi
CLINICAL CALCIUM   25(7) 59-66   2015   [Invited]
Yoshifumi Kimira , Yuri Taniuchi , Sachie Nakatani , Yuusuke Sekiguchi , Hyoun Ju Kim , Jun Shimizu , Midori Ebata , Masahiro Wada , Akiyo Matsumoto , Hiroshi Mano
Phytomedicine   22 1120-1124   2015   [Refereed]
Jun Shimizu, Naoto Asami, Aya Kataoka, Fumihito Sugihara, Naoki Inoue, Yoshifumi Kimira, Masahiro Wada, Hiroshi Mano
Biochem. Biophys. Res. Commun.      2014   [Refereed]
Yoshifumi Kimira, Kana Ogura, Yuri Taniuchi, Aya Kataoka, Naoki Inoue, Fumihito Sugihara, Sachie Nakatani, Jun Shimizu, Masahiro Wada, Hiroshi Mano
Biochem. Biophys. Res. Commun.      2014   [Refereed]
Oral administration of N-acetyl Glucosamine alters the mRNA expression profile of hyaluronan-related genes in mouse skin.
Sachie Nakatani, Hiroshi Mano, Hiroto Nakajima, Tun Shimizu, Kenji Kobata and Masahiro Wada
Chitin and Chitosan Research   18 14-24   2012   [Refereed]
Yuusuke Sekiguchi, Hiroshi Mano, Sachie Nakatani, Jun Shimizu, Kobata Kobata , Masahiro Wada
BMC Res Notes   5 198   2012   [Refereed]
コラーゲンペプチド摂取の意義と効果的な活用法 
MANO Hiroshi
Health Science   28 68-71   2012   [Refereed]

Misc

 
Biochem, Biophys, Res, Commun   297, 323-328    2002
Hiroshi Mano, Yoshiyuki Hakeda, Masayoshi Kumegawa
Cytotechnology   35(1) 17-23   2001
Endogenous production of TGF-β is essential for osteoclastgenesis induced by a combination of receptor activator of NF-KB ligand and macrophage-colony-stimulating factor.
J. immunol.   165 4254-4263   2000
Effects of various bone metabolism-related factors on a pure population of mature osteoclasts
Dentistry in Japan   33 169-173   1999
Biochem. Biophys. Res. Commun   245(2) 419-422   1998
Prostaglandin F2α stimulates tyrosine phosphorylation and mitogen-activated protein kinage in osteoblastic MC3T3-E1 cells ria protein kinase C activation
Endocrinology   138 1821   1997
Down-Regulation of Gap Junctional Intercellular Communication Between Osteoblastic MC3T3-E1 Cells by Basic Fibrolast Growth Factor and a Phorbol Ester (12-O-Tetradecanoylphorbol-13-Acetate)
J. Bone Miner. Res.   12 1165-1173   1997
Yuji YAMAMOTO, Tatsuya YOSHIZAWA, Hiroshi MANO, Shoichi MASUSHIGE, Shigeaki KATO
J. Nutr. Sci. Vitaminol.   42(4) 257-266   1996
Biochem. Biophys. Res. Commun   223(3) 637-642   1996
Biochem. Biophys. Res. Commun   220(3) 515-519   1996
Retinoic acid directly stimulates osteoclastic bone resorption and gene expression of cathepsin K/OC2
Biochem. J   309 721   1995
Formation and function of osteoclasts
27 32   1995
In vivo isomerization of retinoic acids ; Rapid isomer exchange and gene expression
J. Biol. Chem.   269 32700   1995
Shigeaki KATO, Hikaru MORINO, Hiroshi MANO, Shoichi MASUSHIGE
J. Nutr. Sci. Vitaminol   40(1) 1-10   1994
Positive and negative regulation of retinoid X receptor gene expression by thyroid hormone in the rat ; Transcriptional and post-transcriptional controls by thyroid hormone
J. Biol. Chem.   269 1591   1994
Gene expression of retinoid receptors
Abstracts XV international congress of nutrition Adelaide   1 386   1993
Shigeaki KATO, Ken-ichi TAKEYAMA, Ryotaro KOJIMA, Yukihiro YOSHIZAWA, Tadasu FURUSHO, Hiroshi MANO, Shoichi MASUSHIGE
J. Nutr. Sci. Vitaminol.   39(6) 545-554   1993
Biochem. Biophys. Res. Commun.   191(3) 943-949   1993
Retinoid status and RARs expression
Proceedings of the 1st international congress on vitamins and biotactors in lite science   447    1992
Effect of retinoid status on α, β, and γ retinoic acid receptor mRNA levels in various rat tissues
Biochem. J.   286 755   1992

Research Grants & Projects

 
Study on Bone Cell Biology
Study on Swallowing
Study on Cell Differentiation

Patents

 
特願US2012/0258919 : COLLAGEN PEPIDE, DIPEPTIDE AND MALADY INHIBITOR
特願PCT/JP2008071164 : COLLAGEN PEPTIDE, DIPEPTIDE, AND AGENT FOR PREVENTION OF DISEASE