Hiroyuki Nodera

J-GLOBAL         Last updated: Aug 9, 2019 at 17:52
 
Avatar
Name
Hiroyuki Nodera
Affiliation
Kanazawa Medical University
Section
School of Medicine

Research Areas

 
 
  • Clinical internal medicine / Neurology / 

Awards & Honors

 
2017
優秀教員, 優秀教員賞, Graduate School of Medicine
 
Nov 2013
臨床神経生理学の研究, 第三回奨励賞, 日本臨床神経生理学会
 

Published Papers

 
Nodera H, Osaki Y, Yamazaki H, Mori A, Izumi Y, Kaji R
Muscle & nerve   59(2) 224-228   Feb 2019   [Refereed]
Fujita K, Matsubara T, Miyamoto R, Sumikura H, Takeuchi T, Maruyama Saladini K, Kawarai T, Nodera H, Udaka F, Kume K, Morino H, Kawakami H, Hasegawa M, Kaji R, Murayama S, Izumi Y
BMC neurology   19(1) 168   Jul 2019   [Refereed]
Kawarai T, Yamazaki H, Miyamoto R, Takamatsu N, Mori A, Osaki Y, Orlacchio A, Nodera H, Hashiguchi A, Higuchi Y, Yoshimura A, Takashima H, Kaji R
Neuromuscular disorders : NMD   29(6) 422-426   Jun 2019   [Refereed]
Suzuki N, Mori-Yoshimura M, Yamashita S, Nakano S, Murata KY, Mori M, Inamori Y, Matsui N, Kimura E, Kusaka H, Kondo T, Ito H, Higuchi I, Hashiguchi A, Nodera H, Kaji R, Tateyama M, Izumi R, Ono H, Kato M, Warita H, Takahashi T, Nishino I, Aoki M
Orphanet journal of rare diseases   14(1) 155   Jun 2019   [Refereed]
Nodera H
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology   130(2) 303-304   Feb 2019   [Refereed]
Nodera H
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology      Jun 2019   [Refereed]
Oki R, Izumi Y, Nodera H, Sato Y, Nokihara H, Kanai K, Sonoo M, Urushitani M, Nishinaka K, Atsuta N, Kohara N, Shimizu T, Kikuchi H, Oda M, Ikeda K, Nagai M, Komai K, Kojima Y, Kuzume D, Isose S, Shimohama S, Abe K, Ito H, Noda K, Ishihara T, Morita M, Shimohata T, Teramukai S, Kagimura T, Noma K, Yanagawa H, Kuwabara S, Kaji R, JETALS.
JMIR research protocols   7(12) e12046   Dec 2018   [Refereed]
Nodera H, Osaki Y, Yamazaki H, Mori A, Izumi Y, Kaji R
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology   130(5) 617-623   May 2019   [Refereed]
Visualization of Dorsal Root Ganglionitis with Three-Tesla Magnetic Resonance Neurography in Sensory Ataxic Neuropathy Associated with Sjogren's Syndrome
Yoshida Takeshi, Sueyoshi Takeshi, Kinjo Mitsuyo, Suwazono Shugo, Nodera Hiroyuki
ARTHRITIS & RHEUMATOLOGY   70    Sep 2018   [Refereed]
Nodera H, Sogawa K, Takamatsu N, Mori A, Yamazaki H, Izumi Y, Kaji R
The journal of medical investigation : JMI   65(3.4) 274-279   2018   [Refereed]
Kuwabara S, Misawa S, Mori M, Iwai Y, Ochi K, Suzuki H, Nodera H, Tamaoka A, Iijima M, Toda T, Yoshikawa H, Kanda T, Sakamoto K, Kusunoki S, Sobue G, Kaji R, Glovenin-I MMN Study Group.
Journal of the peripheral nervous system : JPNS   23(2) 115-119   Jun 2018   [Refereed]
Misawa Sonoko, Kuwabara Satoshi, Sato Yasunori, Yamaguchi Nobuko, Nagashima Kengo, Katayama Kanako, Sekiguchi Yukari, Iwai Yuta, Amino Hiroshi, Suichi Tomoki, Yokota Takanori, Nishida Yoichiro, Kanouchi Tadashi, Kohara Nobuo, Kawamoto Michi, Ishii Junko, Kuwabara Motoi, Suzuki Hidekazu, Hirata Koichi, Kokubun Norito, Masuda Ray, Kaneko Juntaro, Yabe Ichiro, Sasaki Hidenao, Kaida Ken-ichi, Takazaki Hiroshi, Suzuki Norihiro, Suzuki Shigeaki, Hiroyuki Nodera, Naoko Matsui, Tsuji Shoji, Koike Haruki, Yamasaki Ryo, Kusunki Susumu
The Lancet Neurology   Vol.17(No.6) 519-529   Apr 2018   [Refereed]
Despite the introduction of plasmapheresis and immunoglobulin therapy, many patients with Guillain-Barr? syndrome still have an incomplete recovery. Evidence from pathogenesis studies suggests the involvement of complement-mediated peripheral nerv...
Izumi Y, Miyamoto R, Fujita K, Yamamoto Y, Yamada H, Matsubara T, Unai Y, Tsukamoto A, Takamatsu N, Nodera H, Hayashi S, Oda M, Mori A, Nishida Y, Watanabe S, Ogawa H, Uehara H, Murayama S, Sata M, Kaji R
Frontiers in neurology   9 1099   Dec 2018   [Refereed]
Naoko Matsui, Hiroyuki Nodera, D Kuzume, N Iwasa, Y Unai, W Sakai, Y Miyazaki, H Yamazaki, Yusuke Osaki, A Mori, T Furukawa, A Tsukamoto-Miyashiro, Y Shimatani, M Yamasaki, Yuishin Izumi, S Kusunoki, Kokichi Arisawa, Ryuji Kaji
European Journal of Neurology   Vol.25(No.5) 718-724   May 2018   [Refereed]
Many epidemiological studies of Guillain-Barr? syndrome (GBS) and Fisher syndrome (FS) have been conducted in Europe and America. In contrast, epidemiological studies are rare in Asia where the GBS subtypes differ from those in Western countries. ...
Sogawa K, Nodera H, Takamatsu N, Mori A, Yamazaki H, Shimatani Y, Izumi Y, Kaji R
Radiology   283(2) 492-498   May 2017   [Refereed]
Yamamoto Y, Matsui N, Hiramatsu Y, Miyazaki Y, Nodera H, Izumi Y, Takashima H, Kaji R
Rinsho shinkeigaku = Clinical neurology   57(2) 82-87   Feb 2017   [Refereed]
シャルコー・マリー・トウース病に類似した三頭酵素欠損症の成人例
Yuki Yamamoto, Naoko Matsui, 平松 有, Yoshimichi Miyazaki, Hiroyuki Nodera, Yuishin Izumi, 高嶋 博, Ryuji Kaji
Clinical Neurology   Vol.57(No.2) 82-87   Feb 2017   [Refereed]
Banzrai C, Nodera H, Okada R, Higashi S, Osaki Y, Kaji R
The journal of medical investigation : JMI   64(1.2) 30-38   2017   [Refereed]
山下 雄也, Hiroki Yamazaki, Naoko Matsui, Yoshimichi Miyazaki, 塚本 愛, 西野 一三, 鈴木 重明, 西田 善彦, Hiroyuki Nodera, Yuishin Izumi, Ryuji Kaji
The Journal of the Japanese Society of Internal Medicine   Vol.105(No.8) 1443-1450   Aug 2016   [Refereed]
<p>症例は60歳代,男性.全身倦怠感,四肢脱力を主訴に受診.筋炎としステロイド単独で治療を開始したが,反応性は乏しく,筋病理・抗体検査にて抗SRP抗体陽性壊死性ミオパチー(anti-signal recognition particle immune-mediated necrotizing myopathy:anti-SRP iNM)と診断し,免疫グロブリン大量静注療法,免疫抑制薬を併用したところ,症状の改善を得た.積極的に自己抗体の測定を行うことが壊死性ミオパチー(immune-me...
Toshitaka Kawarai, Kanto Yamasaki, Atsuko Mori, Naoko Takamatsu, Yusuke Osaki, Chimeglkham Banzrai, Chimeglkham Banzrai, Ryosuke Miyamoto, Ryosuke Oki, Lucia Pedace, Antonio Orlacchio, Hiroyuki Nodera, Akihiro Hashiguchi, Yujiro Higuchi, Hiroshi Takashima, Yoshihiko Nishida, Yuishin Izumi, Ryuji Kaji
Journal of Neurology, Neurosurgery, and Psychiatry      Jun 2016   [Refereed]
Kaji Seiji, Toshitaka Kawarai, Miyamoto Ryosuke, Hiroyuki Nodera, Pedace Lucia, Orlacchio Antonio, Yuishin Izumi, Takahashi Ryosuke, Ryuji Kaji
Journal of the Neurological Sciences   Vol.364 45-49   Mar 2016   [Refereed]
Pathogenic mutations in the KIF5A-SPG10 gene, encoding the kinesin HC5A, can be associated with autosomal dominant hereditary spastic paraplegia (ADHSP). It accounts for about 10% of the complicated forms of ADHSP. Peripheral neuropathy, distal up...
Chimeglkham Banzrai, Hiroyuki Nodera, Toshitaka Kawarai, Saki Higashi, Ryo Okada, Atsuko Mori, Yoshimitsu Shimatani, Yusuke Osaki, Ryuji Kaji
Frontiers in Physiology   Vol.7(No.364) 45-49   Feb 2016   [Refereed]
This study aimed to characterize the excitability changes in peripheral motor axons caused by hindlimb unloading (HLU), which is a model of disuse neuromuscular atrophy. HLU was performed in normal 8-week-old male mice by fixing the proximal tail ...
Yoshimitsu Shimatani, Yuta Nakano, Naoko Tsuyama, Shigeo Murayama, Ryosuke Oki, Ryosuke Miyamoto, Nagahisa Murakami, Koji Fujita, Syunsuke Watanabe, Hisanori Uehara, Takashi Abe, Hiroyuki Nodera, Toshitaka Kawarai, Yuishin Izumi, Ryuji Kaji
Neuropathology      Jan 2016   [Refereed]
Among the many potential etiologies for rapidly progressive dementia (RPD), primary central nervous system extranodal NK/T-cell lymphoma, nasal-type (ENKL) is a rare entity. We present the first reported case of autopsy-proven RPD due to ENKL with...
Hiroyuki Nodera, Naoko Takamatsu, Naoko Matsui, Atsuko Mori, Yuka Terasawa, Yoshimitsu Shimatani, Yusuke Osaki, Keiko Maruyama, Yuishin Izumi, Ryuji Kaji
European Journal of Neurology   Vol.23(No.3) 588-596   2016   [Refereed]
Differential diagnosis of sporadic inclusion body myositis (s-IBM) and polymyositis (PM)/dermatomyositis (DM) is difficult and can affect proper disease management. Detection of heterogeneous muscular involvement in s-IBM by muscle sonography coul...
Takahiro Furukawa, Naoko Matsui, Koji Fujita, Hiroyuki Nodera, Fumitaka Shimizu, Katsuichi Miyamoto, Yukitoshi Takahashi, Takashi Kanda, Susumu Kusunoki, Yuishin Izumi, Ryuji Kaji
Neurology? Neuroimmunology & Neuroinflammation   Vol.2(No.5) e138-e138   Aug 2015   [Refereed]
The CSF cytokine profile of patients with MMN is distinct from that of patients with PMA and ALS. The similarity of the cytokine profiles between patients with PMA and ALS suggests that PMA shares common immunologic features with ALS in the CNS, e...
Yusuke Osaki, Naoko Takamatsu, Yoshimitsu Shimatani, Atsuko Mori, Keiko Maruyama, Yoshimichi Miyazaki, Hiroyuki Nodera, Ryuji Kaji
Clinical Neurophysiology   Vol.126(No.8) 1638-1639   Nov 2014   [Refereed]
Yoshimitsu Shimatani, Hiroyuki Nodera, Yoshiko Shibuta, Yoshimichi Miyazaki, Sonoko Misawa, Satoshi Kuwabara, Ryuji Kaji
Clinical Neurophysiology   Vol.126(No.6) 1246-1254   Sep 2014   [Refereed]
Cramp-fasciculation syndrome (CFS) is a heterogeneous condition with multiple underlying causes. Although dysfunction of slow K(+) channels has been reported in patients with CFS, testing all potential candidates for this problem using conventiona...
Takahiro Furukawa, Naoko Matsui, Koji Fujita, Ai Miyashiro, Hiroyuki Nodera, Yuishin Izumi, Fumitaka Shimizu, Katsuichi Miyamoto, Yukitoshi Takahashi, Takashi Kanda, Susumu Kusunoki, Ryuji Kaji
Journal of the Neurological Sciences   Vol.346(No.1-2) 75-79   Aug 2014   [Refereed]
Proinflammatory cytokines may contribute to peripheral nerve demyelination in MMN.
Ai Miyashiro, Naoko Matsui, Yoshimitsu Shimatani, Hiroyuki Nodera, Yuishin Izumi, Satoshi Kawabata, Tomihiro Imai, Masayuki Baba, Tetsuo Komori, Masahiro Sonoo, Takahiro Maezaki, Jun Kawamata, Takefumi Hitomi, Nobuo Kohara, Kimiyoshi Arimura, Shuji Hashimoto, Kokichi Arisawa, Susumu Kusunoki, Ryuji Kaji
Muscle & Nerve   Vol.49(No.3) 357-361   Mar 2014   [Refereed]
Our objective was to do an epidemiologic survey of patients with multifocal motor neuropathy (MMN) in comparison with those with amyotrophic lateral sclerosis (ALS) in Japan. In this retrospective study, we examined 46 patients with MMN and 1,051 ...
Hiroyuki Nodera, Naoko Takamatsu, Yoshimitsu Shimatani, Atsuko Mori, Kenta Sato, Masaya Oda, Yuka Terasawa, Yuishin Izumi, Ryuji Kaji
Clinical Neurophysiology   Vol.125(No.9) 1906-1911   Feb 2014   [Refereed]
Sonographic evaluation of nerve roots and peripheral nerves may be a useful disease marker in ALS to confirm the diagnosis and to potentially monitor the disease progression.
Yohei Mukai, Yoshimitsu Shimatani, Wataru Sako, Kotaro Asanuma, Hiroyuki Nodera, Takashi Sakamoto, Yuishin Izumi, Tomoko Kohda, Shunji Kozaki, Ryuji Kaji
Toxicon   Vol.81 32-36   Feb 2014   [Refereed]
Botulinum neurotoxin type A1 (BoNTs/A1) and type B (BoNT/B) have been used for treating hyperactive muscle contractions. In the present study, we compared the effect of botulinum neurotoxin subtype A2 (6.5 mouse LD50 units A2 neurotoxin, A2NTX) an...
Naoko Matsui, Ai Miyashiro, Yoshimitsu Shimatani, Hiroyuki Nodera, Yuishin Izumi, Satoshi Kuwabara, Masayuki Baba, Tetsuo Komori, Masahiro Sonoo, Takahiro Mezaki, Jun Kawamata, Takefumi Hitomi, Tomihiro Imai, Nobuo Kohara, Kimiyoshi Arimura, Kokichi Arisawa, Susumu Kusunoki, Ryuji Kaji
Clinical & Experimental Neuroimmunology   Vol.4(No.2) 210-215   2013   [Refereed]
Hiroyuki Nodera, B Seward Rutkove
Neuroscience Letters   Vol.518(No.2) 111-116   May 2012   [Refereed]
Peripheral motor nerves have revealed variability in excitability by hyperpolarizing current at specific target response levels, likely reflecting differences in the hyperpolarization-activated current (Ih). Whether such variability in Ih exists i...
Hiroyuki Nodera, B Seward Rutkove
Neuroscience Letters   Vol.518(No.1) 36-40   May 2012   [Refereed]
Persistent Na(+) current (Na(p)) in the peripheral axons play an important functional role in controlling the axonal excitability. Abnormal Na(p) is believed to contribute to neurodegeneration and neuropathic pain, and thus it is an attractive the...
Mamede Carvalho de, Reinhard Dengler, Andrew Eisen, D John England, Ryuji Kaji, Jun Kimura, Kerry Mills, Hiroshi Mitsumoto, Hiroyuki Nodera, Jeremy Shefner, Michael Swash
Muscle & Nerve   Vol.44(No.3) 456-457   Sep 2011   [Refereed]
Yoshiko Shibuta, Hiroyuki Nodera, Atsuko Mori, Takahiro Okita, Ryuji Kaji
Journal of Clinical Neurophysiology   Vol.27(No.5) 350-357   Oct 2010   [Refereed]
Threshold tracking testing has provided novel insights of peripheral nerve excitability in normal and pathologic conditions. However, little has been known on the nerve excitability properties of axons with different stimulation thresholds and the...
Yoshiko Shibuta, Hiroyuki Nodera, Atsuko Nodera, Takahiro Okita, Kotaro Asanuma, Yuishin Izumi, Ryuji Kaji
Clinical Neurophysiology   Vol.121(No.12) 2117-2120   Jun 2010   [Refereed]
Slow potassium current (I(Ks)) is important in controlling nerve excitability and its impairment is known in various neurological diseases, including amyotrophic lateral sclerosis (ALS). I(Ks) gives rise to the late subexcitability phase of the re...
Atsuko Mori, Hiroyuki Nodera, Syunya Nakane, Ryuji Kaji
Clinical Neurology and Neurosurgery   Vol.112(No.8) 713-716   May 2010   [Refereed]
Antiphospholipid antibody syndrome (APS) has been widely recognized to be associated with various neurological complications. In addition to the classical notion of APS as a thrombotic disorder, APS has been suggested to be an autoinflammatory dis...
Hirofumi Maruyama, Hiroyuki Morino, Hidefumi Ito, Yuishin Izumi, Hidemasa Kato, Yasuhito Watanabe, Yoshimi Kinoshita, Masaki Kamada, Hiroyuki Nodera, Hidenori Suzuki, Osamu Komure, Shinya Matsuura, Keitaro Kobatake, Nobutoshi Morimoto, Koji Abe, Naoki Suzuki, Masashi Aoki, Akihiro Kawata, Takeshi Hirai, Takeo Kato, Kazumasa Ogasawara, Asao Hirano, Toru Takumi, Hirofumi Kusaka, Koichi Hagiwara, Ryuji Kaji, Hideshi Kawakami
Nature   Vol.465(No.7295) 223-226   Apr 2010   [Refereed]
Amyotrophic lateral sclerosis (ALS) has its onset in middle age and is a progressive disorder characterized by degeneration of motor neurons of the primary motor cortex, brainstem and spinal cord. Most cases of ALS are sporadic, but about 10% are ...
Atsuko Mori, Hiroyuki Nodera, Yoshiko Shibuta, Takahiro Okita, Hugh Bostock, Ryuji Kaji
Neuroscience Letters   Vol.468(No.3) 248-253   Nov 2009   [Refereed]
Various factors, including maturity, have been shown to influence peripheral nerve excitability measures, but little is known about differences in these properties between axons with different stimulation thresholds. Multiple nerve excitability te...
de Carvalho Mamede, Dengler Reinhard, Eisen Andrew, England John D., Kaji Ryuji, Kimura Jun, Mills Kerry, Mitsumoto Hiroshi, Nodera Hiroyuki, Shefner Jeremy, Swash Michael
CLINICAL NEUROPHYSIOLOGY   119(3) 497-503   Mar 2008   [Refereed]
Maeda Kouji, Kaji Ryuji, Yasuno Katsuhito, Jambaldorj Jamiyansuren, Nodera Hiroyuki, Takashima Hiroshi, Nakagawa Masanori, Makino Satoshi, Tamiya Gen
JOURNAL OF HUMAN GENETICS   52(11) 907-914   Nov 2007   [Refereed]
Hitomi Takefumi, Kaji Ryuji, Murase Nagako, Kohara Nobuo, Mezaki Takahiro, Nodera Hiroyuki, Kawamura Takashi, Ikeda Akio, Shibasaki Hiroshi
CLINICAL NEUROPHYSIOLOGY   118(4) 741-750   Apr 2007   [Refereed]
Nodera Hiroyuki, Takao Shoichiro, Kaji Ryuji
NEUROLOGY   68(5) 383   Jan 2007   [Refereed]
Nodera Hiroyuki, Sato Kenta, Terasawa Yuka, Takamatsu Naoko, Kaji Ryuji
MUSCLE & NERVE   34(3) 380-381   Sep 2006   [Refereed]
Nodera Hiroyuki, Kaji Ryuji
CLINICAL NEUROPHYSIOLOGY   117(9) 1902-1916   Sep 2006   [Refereed]

Misc

 
野寺裕之
末梢神経   29(2) 221‐223   Dec 2018
野寺裕之
末梢神経   29(2) 218‐220   Dec 2018
野寺裕之
日本末梢神経学会学術集会プログラム・抄録   29th 65   Jul 2018
野寺裕之
日本末梢神経学会学術集会プログラム・抄録   29th 64   Jul 2018

Conference Activities & Talks

 
Effectiveness of the medical English course taught by an all-Japanese clinician team
Yamada Yoshiko, Yada Keigo, Hiroyuki Nodera, Koichi Sairyo, Masashi Akaike, Akiyoshi Nishimura
第21回日本医学英語教育学会   28 Jul 2018   
当施設における封入体筋炎のアップデート
Naoko Matsui, Hiroyuki Nodera, 高松 直子, Yuishin Izumi, Ryuji Kaji
稀少難治性筋疾患に関する調査研究班「IBM分科会」(平成29年度)   2 Feb 2018   
Guillain-Barre syndrome in a local area in Japan, 2006-2015: An epidemiological and clinical study of 108 patients
Hanada Kenta, Naoko Matsui, Hiroyuki Nodera, Kuzume Daisuke, Kenta Sato, Iwasa Naoki, Unai Yuki, Saka Waka, Yoshimichi Miyazaki, Yamazaki Hiroki, Yusuke Osaki, Takahiro Furukawa, Yamasaki Masahiro, Yuishin Izumi, Kusunoki Susumu, Kokichi Arisawa, Ryuji Kaji
XX World Congress of Neurology   18 Sep 2017   
テクスチャ解析による筋エコーでのIBM類似疾患との鑑別
Ryuji Kaji, Hiroyuki Nodera, 十川 和樹, 高松 直子, Naoko Matsui
稀少難治性筋疾患に関する調査研究班「IBM分科会」(平成28年度)   17 Feb 2017   
軸索型のギラン・バレー症候群とフィッシャー症候群は春から夏にかけて発症しやすい
Naoko Matsui, 岩佐 直毅, Yoshimichi Miyazaki, Waka Sakai, Takahiro Furukawa, 垂髪 祐樹, Hiroki Yamazaki, Yusuke Ohsaki, Hiroyuki Nodera, 葛目 大輔, 山崎 正博, 楠 進, Ryuji Kaji
第28回日本神経免疫学会学術集会   30 Sep 2016   

Research Grants & Projects

 
Grants-in-Aid for Scientific Research
Project Year: Apr 2017 - Mar 2020    Investigator(s): 野寺 裕之
Grants-in-Aid for Scientific Research
Project Year: Apr 2013 - Mar 2016    Investigator(s): NODERA Hiroyuki
Grants-in-Aid for Scientific Research
Project Year: Apr 2013 - Mar 2015    Investigator(s): OSAKI Yusuke
Grants-in-Aid for Scientific Research
Project Year: Apr 2004 - Mar 2007    Investigator(s): 野寺 裕之
Grants-in-Aid for Scientific Research
Project Year: Apr 2003 - Mar 2005    Investigator(s): KAJI Ryuji