片野いくみ (Katano Ikumi) - マイポータル

基本情報

学位: 博士（医学）(2016年3月慶應義塾大学)

J-GLOBAL ID: 201801020192645440
researchmap会員ID: B000317013

論文

Multiomics analysis reveals the genetic and epigenetic features of high-risk NK cell-type chronic active EBV infection

Ryo Akazawa, Takashi Mikami, Masaki Yamada, Itaru Kato, Hirohito Kubota, Satoshi Saida, Yoshinori Uchihara, Yuriko Ishikawa, Tatsuya Kamitori, Keiji Tasaka …

Blood Journal 2025年7月30日
Efficient differentiation of human neutrophils with recapitulation of emergency granulopoiesis in human G-CSF knockin humanized mice.

Ito R, Katano I, Kwok IWH, Ng LG, Ida-Tanaka M, Ohno Y, Mu Y, Morita H, Nishinaka E, Nishime C …

Cell reports 2022年12月1日
Development of a novel humanized mouse model for improved evaluation of in vivo anti-cancer effects of anti-PD-1 antibody.

Ikumi Katano, Asami Hanazawa, Iyo Otsuka, Takuya Yamaguchi, Misa Mochizuki, Kenji Kawai, Ryoji Ito, Motohito Goto, Takahiro Kagawa, Takeshi Takahashi

Scientific reports 11(1) 21087-21087 2021年10月26日
Bovine β-lactoglobulin-induced passive systemic anaphylaxis model using humanized NOG hIL-3/hGM-CSF transgenic mice.

Ryoji Ito, Ikumi Katano, Iyo Otsuka, Takeshi Takahashi, Hiroshi Suemizu, Mamoru Ito, Peter J Simons

International immunology 33(3) 183-189 2021年3月1日査読有り
Generation of Novel Human Red Blood Cell-Bearing Humanized Mouse Models Based on C3-Deficient NOG Mice.

Takuya Yamaguchi, Ikumi Katano, Iyo Otsuka, Ryoji Ito, Misa Mochizuki, Motohito Goto, Takeshi Takahashi

Frontiers in immunology 12 671648-671648 2021年
Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9.

Yuyo Ka, Ikumi Katano, Eiko Nishinaka, Jochen Welcker, Misa Mochizuki, Kenji Kawai, Motohito Goto, Kayo Tomiyama, Tomoyuki Ogura, Taichi Yamamoto …

Immunology letters 229 55-61 2021年1月
Report of the use of patient-derived xenograft models in the development of anticancer drugs in Japan.

Ryo Tsumura, Yoshikatsu Koga, Akinobu Hamada, Takeshi Kuwata, Hiroki Sasaki, Toshihiko Doi, Katsuji Aikawa, Akihiro Ohashi, Ikumi Katano, Yoshinori Ikarashi …

Cancer science 111(9) 3386-3394 2020年9月査読有り
Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse.

Ikumi Katano, Ryoji Ito, Kenji Kawai, Takeshi Takahashi

Frontiers in immunology 11 532684-532684 2020年査読有り
Exacerbation of pathogenic Th17-cell-mediated cutaneous graft-versus-host-disease in human IL-1β and IL-23 transgenic humanized mice.

Ito R, Katano I, Otsuka I, Hanazawa A, Takahashi T, Kawai K, Yagoto M, Goto M, Ogura T, Takahashi R …

Biochemical and biophysical research communications 516(2) 480-485 2019年8月20日査読有り
Recent Advances in Allergy Research Using Humanized Mice.

Ryoji Ito, Shuichiro Maruoka, Yasuhiro Gon, Ikumi Katano, Takeshi Takahashi, Mamoru Ito, Kenji Izuhara, Satoshi Nunomura

International journal of molecular sciences 20(11) 2019年6月4日査読有り
Human Interleukin-34 facilitates microglia-like cell differentiation and persistent HIV-1 infection in humanized mice.

Saumi Mathews, Amanda Branch Woods, Ikumi Katano, Edward Makarov, Midhun B Thomas, Howard E Gendelman, Larisa Y Poluektova, Mamoru Ito, Santhi Gorantla

Molecular neurodegeneration 14(1) 12-12 2019年3月5日査読有り
A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis.

Ryoji Ito, Shuichiro Maruoka, Kaori Soda, Ikumi Katano, Kenji Kawai, Mika Yagoto, Asami Hanazawa, Takeshi Takahashi, Tomoyuki Ogura, Motohito Goto …

JCI insight 3(21) 2018年11月2日査読有り
Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses.

Tomonori Yaguchi, Asuka Kobayashi, Takashi Inozume, Kenji Morii, Haruna Nagumo, Hiroshi Nishio, Takashi Iwata, Yuyo Ka, Ikumi Katano, Ryoji Ito …

Cellular & molecular immunology 15(11) 953-962 2018年11月査読有り
Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice.

Asami Hanazawa, Ryoji Ito, Ikumi Katano, Kenji Kawai, Motohito Goto, Hiroshi Suemizu, Yutaka Kawakami, Mamoru Ito, Takeshi Takahashi

Frontiers in immunology 9 152-152 2018年査読有り
Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse.

Ikumi Katano, Chiyoko Nishime, Ryoji Ito, Tsutomu Kamisako, Takuma Mizusawa, Yuyo Ka, Tomoyuki Ogura, Hiroshi Suemizu, Yutaka Kawakami, Mamoru Ito …

Scientific reports 7(1) 17230-17230 2017年12月8日査読有り
A novel in vivo model for predicting myelotoxicity of chemotherapeutic agents using IL-3/GM-CSF transgenic humanized mice

R. Ito, D. Nagai, N. Igo, Y. Okuda, K. Sekine, E. Ichimura, I. Katano, T. Mizushima, M. Goto, Y. Ohnishi …

TOXICOLOGY LETTERS 281 152-157 2017年11月査読有り
A Novel Xenogeneic Graft-Versus-Host Disease Model for Investigating the Pathological Role of Human CD4(+) or CD8(+) T Cells Using Immunodeficient NOG Mice

R. Ito, I. Katano, K. Kawai, M. Yagoto, T. Takahashi, Y. Ka, T. Ogura, R. Takahashi, M. Ito

AMERICAN JOURNAL OF TRANSPLANTATION 17(5) 1216-1228 2017年5月査読有り
Antitumor Effect of Programmed Death-1 (PD-1) Blockade in Humanized the NOG-MHC Double Knockout Mouse.

Tadashi Ashizawa, Akira Iizuka, Chizu Nonomura, Ryota Kondou, Chie Maeda, Haruo Miyata, Takashi Sugino, Koichi Mitsuya, Nakamasa Hayashi, Yoko Nakasu …

Clinical cancer research : an official journal of the American Association for Cancer Research 23(1) 149-158 2017年1月1日査読有り
NOG-hIL-4-Tg, a new humanized mouse model for producing tumor antigen-specific IgG antibody by peptide vaccination.

Yoshie Kametani, Ikumi Katano, Asuka Miyamoto, Yusuke Kikuchi, Ryoji Ito, Yukari Muguruma, Banri Tsuda, Sonoko Habu, Yutaka Tokuda, Kiyoshi Ando …

PloS one 12(6) e0179239 2017年査読有り
Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis.

Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Motohito Goto, Hayato Abe, Seiya Mizuno, Kenji Kawai, Fumihiro Sugiyama, Mamoru Ito

Frontiers in immunology 8 2017-2017 2017年査読有り

もっとみる

MISC

The specific antibody production against HER2 peptide CH401MAP in NOG-IL4-Tg mice

A. Miyamoto, Katano, I, Y. Kikuchi, B. Tsuda, Y. Tokuda, M. Ito, S. Habu, Y. Kametani

EUROPEAN JOURNAL OF IMMUNOLOGY 46 1218-1218 2016年8月
Pharmacodynamic evaluation of ADCC mediated effects in humanized IL2 or IL15 NOG mice models

Caroline Mignard, Jean-Francois Mirjolet, Olivier Duchamp, Yasuyuki Ohnishi, Ikumi Katano, Mamoru Ito

CANCER RESEARCH 74(19) 2014年10月
In vivo ADCC-mediated antitumor activity study with new preclinical humanized models

Caroline Mignard, Olivier Duchamp, Jean-Francois Mirjolet, Yasuyuki Ohnishi, Ikumi Katano, Mamoru Ito

MOLECULAR CANCER THERAPEUTICS 12(11) 2013年11月

共同研究・競争的資金等の研究課題

ヒトミクログリアが自然発生するヒト化マウスを用いた無菌環境での脳恒常性破綻の解明

日本学術振興会科学研究費助成事業基盤研究(C) 2022年4月 - 2025年3月

片野いくみ
ヒト成熟NK細胞を長期間維持できるヒト化マウスを用いた生体内細胞傷害検証系の開発

日本学術振興会科学研究費助成事業若手研究(B) 2016年4月 - 2019年3月

片野いくみ
ヒトNK細胞が増殖する新規ヒト化マウスによるin vivo細胞傷害性試験系の開発

日本学術振興会科学研究費助成事業若手研究(B) 2013年4月 - 2016年3月

片野いくみ
ヒト化ＮＯＧマウスを基盤とした個別医療に対応するヒト型実験システムの開発

日本学術振興会科学研究費助成事業基盤研究(S) 2010年4月 - 2015年3月

伊藤守, 安藤潔, 小柳義夫, 亀谷美恵, 高橋武司, 中畑龍俊, 八幡崇, 末水洋志, 江藤智生, 伊藤亮治, 片野いくみ

片野いくみ

基本情報

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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