Jun Hatakeyama

J-GLOBAL         Last updated: Dec 10, 2019 at 16:54
Jun Hatakeyama
Kumamoto University

Research Interests


Research Areas


Published Papers

Hatakeyama J, Shimamura K
Cerebral cortex (New York, N.Y. : 1991)   29(9) 3725-3737   Aug 2019   [Refereed]
Hatakeyama J, Sato H, Shimamura K
Development, growth & differentiation   59(4) 286-301   May 2017   [Refereed]
Ha T, Moon KH, Dai L, Hatakeyama J, Yoon K, Park HS, Kong YY, Shimamura K, Kim JW
Cell reports   19(2) 351-363   Apr 2017   [Refereed]
Kameyama H, Kudoh S, Hatakeyama J, Matuo A, Ito T
Acta histochemica et cytochemica   50(1) 1-9   Feb 2017   [Refereed]
Hatakeyama J, Wakamatsu Y, Nagafuchi A, Kageyama R, Shigemoto R, Shimamura K
Development (Cambridge, England)   141 1671-1682   Apr 2014   [Refereed]
Zhang J, Hatakeyama J, Eto K, Abe SI
General and comparative endocrinology      Apr 2014   [Refereed]
Guiu J, Shimizu R, D'Altri T, Fraser ST, Hatakeyama J, Bresnick EH, Kageyama R, Dzierzak E, Yamamoto M, Espinosa L, Bigas A
The Journal of experimental medicine   210(1) 71-84   Jan 2013   [Refereed]
Hatakeyama J, Shimamura K
Development, growth & differentiation   50 449-452   Aug 2008   [Refereed]
Hirata H, Watanabe T, Hatakeyama J, Sprague SM, Saint-Amant L, Nagashima A, Cui WW, Zhou W, Kuwada JY
Development (Cambridge, England)   134(15) 2771-2781   Aug 2007   [Refereed]
Baek JH, Hatakeyama J, Sakamoto S, Ohtsuka T, Kageyama R
Development (Cambridge, England)   133(13) 2467-2476   Jul 2006   [Refereed]
Hatakeyama J, Kageyama R
Cerebral cortex (New York, N.Y. : 1991)   16 Suppl 1 i132-7   Jul 2006   [Refereed]
Hatakeyama J, Sakamoto S, Kageyama R
Developmental neuroscience   28 92-101   2006   [Refereed]
Kageyama R, Ohtsuka T, Hatakeyama J, Ohsawa R
Experimental cell research   306(2) 343-348   Jun 2005   [Refereed]
Hatakeyama J, Bessho Y, Katoh K, Ookawara S, Fujioka M, Guillemot F, Kageyama R
Development (Cambridge, England)   131(22) 5539-5550   Nov 2004   [Refereed]
Takatsuka K, Hatakeyama J, Bessho Y, Kageyama R
Brain research   1004 148-155   Apr 2004   [Refereed]
Hatakeyama J, Kageyama R
Seminars in cell & developmental biology   15 83-89   Feb 2004   [Refereed]
Kageyama R, Hirata H, Hatakeyama J
International review of neurobiology   55 123-147   2003   [Refereed]
Hatakeyama J, Kageyama R
Methods (San Diego, Calif.)   28 387-395   Dec 2002   [Refereed]
Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice.
Hide T, Hatakeyama J, Kimura-Yoshida C, Tian E, Takeda N, Ushio Y, Shiroishi T, Aizawa S, Matsuo I
Development (Cambridge, England)   129 4347-4357   Sep 2002   [Refereed]
Roles of homeobox and bHLH genes in specification of a retinal cell type.
Hatakeyama J, Tomita K, Inoue T, Kageyama R
Development (Cambridge, England)   128 1313-1322   Apr 2001   [Refereed]

Conference Activities & Talks

Roles of cerebrospinal fluid for embryonic neural progenitor cells [Invited]
Jun Hatakeyama
Joint annual meeting of 71st JSCB & 19th PSSJ   24 Jun 2019   
A novel role of Fgf signaling for the roof plate formation in chick hindbrain
Jun Hatakeyama
52nd annual meeting of the Japanese society of developmental biologists   15 May 2019   
Novel roles of Fgf8 which is expressed in ventral region of the developing chick hindbrain
Jun Hatakeyama
16 Mar 2015   
A mechanism that controls "the pace of neurogenesis" through Notch signaling in the developing cerebral cortex
Hatakeyama J, Shimamura K.
Neuroscience2014   11 Sep 2014   
Pace control of neurogenesis regulated by transient retention of the apical end foot of differentiating cells via Notch signaling
Shimamura K, Hatakeyama J, Sato-Takemoto H
Cortical Development, Crete, Greece   23 May 2014   
A novel boundary in the developing central nervous system
Hatakeyama J, Lumsden A, Kageyama R, Shimamura K
Exciting Biologies 2013   17 Oct 2013   
The role of the adherens junction for regulation of neurogenesis via Notch signaling
Hatakeyama J
Institute of Science and Technology (IST), Klosterneuburg, Austria   11 Oct 2013   
Hatakeyama J, Wakamatsu Y, Shigemoto R, Nagafuchi A, Shimamura K
Neuro2013   22 Jun 2013   
The apical endfoot of nascent neuron controls the pace of neurogenesis through the regulation of Notch signaling.
Jun Hatakeyama
CDB symposium 2013   Mar 2013   
Retention of adherens junctions in nascent neurons controls the pace of neurogenesis through Notch signaling.
Hatakeyama J
National Institute for Medical Research,  London, UK   29 Nov 2012   
The pace of neurogenesis is controlled by cellular microstructure.
Hatakeyama J
Institute of Jacques Monod, Paris, France   22 Nov 2012   
Regulation of Notch signaling through the adherens junction in neurogenesis and somitogenesis
Jun Hatakeyama
Joint Meeting of JSDB 45th & JSCB 64th   May 2012   
Pace control of neurogenesis by the apical endfeet of neurons in the cortical  development
Jun Hatakeyama
Mar 2012   
How is the pace of neurogenesis controlled?
Hatakeyama J
IMEG, Kumamoto University   20 Feb 2012   
The adherens junction serve as a switch for neurogenesis by facilitating Notch-Delta interaction in the vertebrate
Jun Hatakeyama
Sep 2011   
The adherens junction serves as a switch for neurogenesis via Notch signaling
Jun Hatakeyama
Notch Meeting:Notch and Stem Cells   Oct 2010   
The adherens junction serves as a switch for neurogenesis
Jun Hatakeyama
Jun 2010   
Role of the adherens junction in neurogenesis
Jun Hatakeyama
16th International Society of Developmental Biologists Congress 2009   Sep 2009   
A novel boundary in the developing central nervous system
Jun Hatakeyama
Mar 2009   
Nobel boundary cells in the developing central nervous system
Jun Hatakeyama
Boundary cells in the developing central nervous system
Jun Hatakeyama
1st Young Embryologist Meeting   24 Nov 2008   
The adherens junction is required for the regulation of neural differentiation
Jun Hatakeyama
Sep 2008   
Morphological features of the apical surface of the neuroepithelium
Jun Hatakeyama
Where does Notch interact with its ligand in the neuroepithelia?
Jun Hatakeyama
Hes genes regulate formation of the central nervous system by control of the timing of neural stem cell differentiation and formation of the cranial and spinal nervous systems
Jun Hatakeyama
15th International Society of Developmental Biologists Congress 2005   Sep 2005   
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation.
Jun Hatakeyama
The role of progenitor cells in neural tube morphogenesis
Jun Hatakeyama
CDB Symposium 2003   Mar 2003   
The role of radial glial cells in neural tube morphogenesis
Jun Hatakeyama
Roles of homeobox and bHLH genes in specification of a retinal cell type
Jun Hatakeyama
The 14th International Congress of Developmental Biology   2001   

Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(スタートアップ), 研究活動スタート支援)
Project Year: 2009 - 2010    Investigator(s): Jun HATAKEYAMA
Development of the central nervous system (CNS) requires an exquisite balance between proliferation and differentiation of the neural progenitors. The balance must be important for forming regional histogenesis. However the mechanisms remain poorl...