Hitoshi Takano

J-GLOBAL         Last updated: Nov 22, 2019 at 11:09
 
Avatar
Name
Hitoshi Takano
E-mail
htakanonms.ac.jp
Affiliation
Nippon Medical School
Research funding number
90277533
ORCID ID
0000-0002-8821-4884

Research Interests

 
 

Research Areas

 
 

Academic & Professional Experience

 
 
   
 
Nippon Medical School 
 
Apr 2012
 - 
Today
Assistant Professor, Nippon Medical School Faculty of Medicine, Department of Medicine
 
Nov 1996
 - 
Nov 1999
Research Fellow, Division of Cardiology, University of Louisville
 

Awards & Honors

 
Nov 2006
Scientific Award Clinical Session, 2006 Scientific Sessions of the American Heart Association
 
Oct 2006
Datascope Scholarship Award, TCT2006
 
Feb 1998
Young Investigator Award in the meeting of Vascular and Myocardial Aspects of Ischemic Heart Disease, American Heart Association
 
Jul 1998
Fellowship Award, American Heart Association Kentucky Affiliate
 

Published Papers

 
Biolè C, Huczek Z, Nuñez-Gil I, Boccuzzi G, Autelli M, Montefusco A, Trabattoni D, Ryan N, Venuti G, Imori Y, Takano H, Matsuda J, Shimizu W, Muscoli S, Montabone A, Wojakowski W, Rognoni A, Helft G, Gallo D, Parma R, De Luca L, Figini F, Mitomo S, Pennone M, Mattesini A, Templin C, Quadri G, Wańha W, Cerrato E, Smolka G, Protasiewicz M, Kuliczkowski W, Rolfo C, Cortese B, Capodanno D, Chieffo A, Morbiducci U, Iannaccone M, Gili S, di Mario C, D'Amico M, Romeo F, Lüscher TF, Sheiban I, Escaned J, Varbella F, D'Ascenzo F
International journal of cardiology   290 64-69   Sep 2019   [Refereed]
Hayashi H, Iwasaki YK, Hachisuka M, Mimuro R, Maru Y, Fujimoto Y, Oka E, Noma S, Sangen H, Yamamoto T, Tokita Y, Yodogawa K, Takano M, Takano H, Shimizu W
JACC. Clinical electrophysiology   5(3) 401-403   Mar 2019   [Refereed]
Imori Y, Iwasaki YK, Takano H, Shimizu W
BMJ case reports   2018    Oct 2018   [Refereed]
Kubota Y, Yamamoto T, Tara S, Tokita Y, Yodogawa K, Iwasaki Y, Takano H, Tsukada Y, Asai K, Miyamoto M, Miyauchi Y, Kodani E, Sato N, Tanabe J, Shimizu W
Diabetes therapy : research, treatment and education of diabetes and related disorders   9(5) 2107-2116   Oct 2018   [Refereed]
Sangen H, Imori Y, Tara S, Yamamoto T, Takano H, Shimizu W
European heart journal   39(22) 2118   Jun 2018   [Refereed]
Amano Y, Kitamura M, Takano H, Yanagisawa F, Tachi M, Suzuki Y, Kumita S, Takayama M
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine   17(2) 120-131   Apr 2018   [Refereed]
Matsuda J, Kitamura M, Takayama M, Imori Y, Shibuya J, Kubota Y, Sangen H, Nakamura S, Takano H, Asai K, Shimizu W
Heart and vessels   33(3) 246-254   Mar 2018   [Refereed]
Kiriyama T, Fukushima Y, Hayashi H, Takano H, Kumita SI
Annals of nuclear medicine   32(1) 22-33   Jan 2018   [Refereed]
Sugihara Y, Fukushima Y, Kumita SI, Takano H, Shimizu W
European journal of hybrid imaging   2(1) 5   2018   [Refereed]
Furuse E, Takano H, Yamamoto T, Kubota Y, Yoshizane T, Kitamura M, Miyachi H, Hosokawa Y, Shimizu W
Heart and vessels   32(12) 1432-1438   Dec 2017   [Refereed]
Sangen H, Tara S, Tanaka T, Takano H, Tanaka K, Shimizu W
Journal of vascular surgery cases and innovative techniques   3(4) 236-239   Dec 2017   [Refereed]
Kitamura M, Amano Y, Takayama M, Shibuya J, Matsuda J, Sangen H, Nakamura S, Takano H, Asai K, Kumita S, Shimizu W
The American journal of cardiology   120(1) 124-130   Jul 2017   [Refereed]
Aoyama R, Takano H, Suzuki K, Kubota Y, Inui K, Tokita Y, Shimizu W
Coronary artery disease   28(3) 225-231   May 2017   [Refereed]
Aoyama R, Takano H, Kobayashi Y, Kitamura M, Asai K, Amano Y, Kumita SI, Shimizu W
PloS one   12(11) e0188479-e0188494   Nov 2017   [Refereed]
Komiyama H, Takano H, Nakamura S, Takano M, Hata N, Yasushi M, Seino Y, Mizuno K, Shimizu W
Cardiovascular ultrasound   14(1) 47   Nov 2016   [Refereed]
Inui K, Tachi M, Saito T, Kubota Y, Murai K, Kato K, Takano H, Amano Y, Asai K, Shimizu W
Magnetic resonance imaging   34(8) 1141-1145   Oct 2016   [Refereed]
Kimura Y, Tanaka N, Okura H, Yoshida K, Akabane M, Takayama T, Hirayama A, Tada T, Kimura T, Takano H, Mizuno K, Inami T, Yoshino H, Yamashina A
Cardiovascular intervention and therapeutics   31(1) 29-37   Jan 2016   [Refereed]
Saito T, Asai K, Sato S, Hayashi M, Adachi A, Sasaki Y, Takano H, Mizuno K, Shimizu W
Autophagy   12(3) 579-587   2016   [Refereed]
Suzuki K, Takano H, Kubota Y, Inui K, Nakamura S, Tokita Y, Kato K, Asai K, Shimizu W
PloS one   11(12) e0167645-e0167655   Dec 2016   [Refereed]
Tomiyama T, Ishihara K, Suda M, Kanaya K, Sakurai M, Takahashi N, Takano H, Nitta K, Hakozaki K, Kumita S
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology   22(5) 998-1007   Oct 2015   [Refereed]
Shibuya J, Nakamura S, Komiyama H, Kato K, Inami S, Takano H, Mizuno K, Shimizu W
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology   11(6) e1   Oct 2015   [Refereed]
Miyake K, Akimoto T, Hanada Y, Nagoya H, Kodaka Y, Ueki N, Kusunoki M, Kawagoe T, Futagami S, Takahashi Y, Takano H, Sakamoto C
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver   47(9) 757-762   Sep 2015   [Refereed]
Kitamura M, Takayama M, Matsuda J, Kubota Y, Nakamura S, Takano H, Asai K, Shimizu W
The American journal of cardiology   116(6) 945-951   Sep 2015   [Refereed]
Sangen H, Tanabe J, Takano H, Shimizu W
BMJ case reports   2015    Sep 2015   [Refereed]
Shiomura R, Nakamura S, Takano H, Kato K, Inui K, Kubota Y, Komiyama H, Murai K, Asai K, Shimizu W
The American journal of cardiology   116(4) 515-519   Aug 2015   [Refereed]
Tomiyama T, Kumita S, Ishihara K, Suda M, Sakurai M, Hakozaki K, Hashimoto H, Takahashi N, Takano H, Kobayashi Y, Kiriyama T, Fukushima Y, Shimizu W
The international journal of cardiovascular imaging   31(5) 1089-1095   Jun 2015   [Refereed]
Koen M, Nakamura S, Takano H, Shimizu W
BMJ case reports   2015    Jun 2015   [Refereed]
Saito T, Asai K, Sato S, Takano H, Mizuno K, Shimizu W
European heart journal   36(12) 724-732   Mar 2015   [Refereed]
Nakamura S, Asai K, Kubota Y, Murai K, Takano H, Tsukada YT, Shimizu W
Clinical research in cardiology : official journal of the German Cardiac Society   104(3) 208-216   Mar 2015   [Refereed]
Nakamura S, Inami S, Murai K, Takano M, Takano H, Asai K, Yasutake M, Shimizu W, Mizuno K
Clinical research in cardiology : official journal of the German Cardiac Society   103(12) 1015-1021   Dec 2014   [Refereed]
Nakamura S, Takano H, Matsuda J, Chinen D, Kitamura M, Murai K, Asai K, Yasutake M, Takayama M, Shimizu W
BMJ open   4(9) e005968   Sep 2014   [Refereed]
Nakamura S, Takano H, Kubota Y, Asai K, Shimizu W
Journal of thrombosis and haemostasis : JTH   12(7) 1086-1095   Jul 2014   [Refereed]
Kitamura M, Kubota Y, Takano H, Takayama M
European heart journal   35(4) 241   Jan 2014   [Refereed]
Ikeda T, Saito T, Takagi G, Sato S, Takano H, Hosokawa Y, Hayashi M, Asai K, Yasutake M, Mizuno K
Circulation   128(25) 2811-2812   Dec 2013   [Refereed]
Saito T, Asai K, Sato S, Takano H, Adach A, Sasaki Y, Namimatsu S, Mizuno K
International journal of cardiology   168(5) 4843-4844   Oct 2013   [Refereed]
Saito T, Asai K, Sato S, Takagi G, Takano H, Takahashi H, Yasutake M, Mizuno K
International journal of cardiology   168(1) 144-150   Sep 2013   [Refereed]
Yoshida A, Takano H, Asai K, Yasutake M, Amano Y, Kumita S, Shimizu W, Mizuno K
Journal of cardiac failure   19(7) 445-453   Jul 2013   [Refereed]
Takano H, Ohba T, Yamamoto E, Miyachi H, Inui K, Kawanaka H, Kamiya M, Kikuchi A, Takahashi Y, Tanabe J, Inami S, Takagi G, Asai K, Yasutake M, Ibuki C, Tanaka K, Kusama Y, Seino Y, Munakata K, Mizuno K, PRIMITIVE Study Investigators.
The American journal of cardiology   111(12) 1688-1693   Jun 2013   [Refereed]
Hosokawa Y, Yamamoto T, Yabuno Y, Hara K, Aokage T, Nakazato K, Suzuki H, Suzuki M, Ueno A, Munakata R, Tokita Y, Yamamoto E, Akutsu K, Takano H, Sato N, Takayama M, Tanaka K, Mizuno K
International journal of cardiology   158(1) e20-1   Jun 2012   [Refereed]
Disruption of atherosclerotic neointima seven years after bare metal stent deployment.
Inami S, Takano M, Kato K, Yoshida A, Nakamura S, Murai K, Tokita Y, Takagi G, Takano H, Asai K, Yasutake M, Mizuno K
International heart journal   53(4) 261-262   2012   [Refereed]
Takagi G, Miyamoto M, Tara S, Takagi I, Takano H, Yasutake M, Tabata Y, Mizuno K
Tissue engineering. Part A   17(21-22) 2787-2794   Nov 2011   [Refereed]
Tara S, Takagi G, Miyamoto M, Kirinoki-Ichikawa S, Yamamoto T, Takano H, Takagi I, Yasutake M, Tabata Y, Mizuno K
Geriatrics & gerontology international   11(4) 527-530   Oct 2011   [Refereed]
Mizuno K, Wang Z, Inami S, Takano M, Yasutake M, Asai K, Takano H
Cardiovascular intervention and therapeutics   26(2) 89-97   May 2011   [Refereed]
Aoki S, Nakagomi A, Asai K, Takano H, Yasutake M, Seino Y, Mizuno K
Journal of cardiology   57(2) 202-207   Mar 2011   [Refereed]
Aoki A, Ozaki K, Sato H, Takahashi A, Kubo M, Sakata Y, Onouchi Y, Kawaguchi T, Lin TH, Takano H, Yasutake M, Hsu PC, Ikegawa S, Kamatani N, Tsunoda T, Juo SH, Hori M, Komuro I, Mizuno K, Nakamura Y, Tanaka T
Journal of human genetics   56(1) 47-51   Jan 2011   [Refereed]
Tara S, Miyamoto M, Takagi G, Fukushima Y, Kirinoki-Ichikawa S, Takano H, Takagi I, Mizuno H, Yasutake M, Kumita S, Mizuno K
Annals of vascular diseases   4(1) 24-31   2011   [Refereed]
Kiriyama T, Toba M, Fukushima Y, Hayashi H, Takano H, Mizuno K, Kumita S
Circulation journal : official journal of the Japanese Circulation Society   75(7) 1670-1677   2011   [Refereed]
Nakagomi A, Kodani E, Takano H, Uchida T, Sato N, Ibuki C, Kusama Y, Seino Y, Munakata K, Mizuno K, Takano T
Circulation journal : official journal of the Japanese Circulation Society   75(7) 1696-1705   2011   [Refereed]
Takano M, Yamamoto M, Murakami D, Takano H, Asai K, Yasutake M, Seino Y, Mizuno K
International journal of cardiology   141(3) e51-3   Jun 2010   [Refereed]
Kawanaka H, Takagi G, Miyamoto M, Tara S, Takagi I, Takano H, Yasutake M, Tabata Y, Mizuno K
The American journal of the medical sciences   338(4) 341-342   Oct 2009   [Refereed]
Ogano M, Iwasaki YK, Takano H, Takayama M, Takano T, Fukuda Y
Internal medicine (Tokyo, Japan)   45(6) 355-358   2006   [Refereed]
Ogano M, Takano H, Fukuma N, Takayama M, Takano T, Miyagi Y, Ochi M, Shimizu K, Kitamura H
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi   72(5) 285-289   Oct 2005   [Refereed]
Yoshida H, Kusama Y, Kodani E, Yasutake M, Takano H, Atarashi H, Kishida H, Takano T
International heart journal   46(5) 877-887   Sep 2005   [Refereed]
Therapeutic angiogenesis by autologous bone marrow cell implantation for refractory chronic peripheral arterial disease using assessment of neovascularization by 99mTc-tetrofosmin (TF) perfusion scintigraphy.
Miyamoto M, Yasutake M, Takano H, Takagi H, Takagi G, Mizuno H, Kumita S, Takano T
Cell transplantation   13(4) 429-437   2004   [Refereed]
Kodani E, Xuan YT, Shinmura K, Takano H, Tang XL, Bolli R
American journal of physiology. Heart and circulatory physiology   283(5) H1943-57   Nov 2002   [Refereed]
Kojima S, Shida M, Takano H, Inami S, Yodogawa K, Yokoyama H, Kuramochi M
Hypertension research : official journal of the Japanese Society of Hypertension   24(5) 595-598   Sep 2001   [Refereed]
Kodani E, Shinmura K, Xuan YT, Takano H, Auchampach JA, Tang XL, Bolli R
American journal of physiology. Heart and circulatory physiology   281(2) H959-68   Aug 2001   [Refereed]
Kojima S, Shida M, Tanaka K, Takano H, Yokoyama H, Kuramochi M
American journal of hypertension   14(6 Pt 1) 516-523   Jun 2001   [Refereed]
Kojima S, Shida M, Tanaka K, Takano H, Yokoyama H, Kuramochi M
Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis   5(1) 2-6   Feb 2001   [Refereed]
Hitoshi Takano, Xian Liang Tang, Eitaro Kodani, Roberto Bolli, Roberto Bolli
American Journal of Physiology - Heart and Circulatory Physiology   279(5) H2372-2381   Dec 2000   [Refereed]
H. Takano, X. L. Tang, R. Bolli
Nippon Medical School   279(5) H2350-2359   Dec 2000   [Refereed]
Xuan YT, Tang XL, Qiu Y, Banerjee S, Takano H, Han H, Bolli R
American journal of physiology. Heart and circulatory physiology   279(5) H2360-71   Nov 2000   [Refereed]
Shinmura K, Tang XL, Takano H, Hill M, Bolli R
The American journal of physiology   277(6) H2495-503   Dec 1999   [Refereed]
Banerjee S, Tang XL, Qiu Y, Takano H, Manchikalapudi S, Dawn B, Shirk G, Bolli R
The American journal of physiology   277(6) H2488-94   Dec 1999   [Refereed]
Bifunctional role of protein tyrosine kinases in late preconditioning against myocardial stunning in conscious rabbits.
Dawn B, Xuan YT, Qiu Y, Takano H, Tang XL, Ping P, Banerjee S, Hill M, Bolli R
Circulation research   85(12) 1154-1163   Dec 1999   [Refereed]
Demonstration of selective protein kinase C-dependent activation of Src and Lck tyrosine kinases during ischemic preconditioning in conscious rabbits.
Ping P, Zhang J, Zheng YT, Li RC, Dawn B, Tang XL, Takano H, Balafanova Z, Bolli R
Circulation research   85(6) 542-550   Sep 1999   [Refereed]
Jones WK, Flaherty MP, Tang XL, Takano H, Qiu Y, Banerjee S, Smith T, Bolli R.
J Mol Cell Cardiol   31(8) 1469-1481   Aug 1999   [Refereed]
Increased protein synthesis is necessary for the development of late preconditioning against myocardial stunning.
Rizvi A, Tang XL, Qiu Y, Xuan YT, Takano H, Jadoon AK, Bolli R
The American journal of physiology   277(3 Pt 2) H874-84   Sep 1999   [Refereed]
Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits.
Xuan YT, Tang XL, Banerjee S, Takano H, Li RC, Han H, Qiu Y, Li JJ, Bolli R.
Circ Res   84(9) 1095-1109   May 1999   [Refereed]
Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning.
Ping P, Takano H, Zhang J, Tang XL, Qiu Y, Li RC, Banerjee S, Dawn B, Balafonova Z, Bolli R.
Circ Res   84(5) 587-604   Mar 1999   [Refereed]
Bolli R, Dawn B, Tang XL, Qiu Y, Ping P, Xuan YT, Jones WK, Takano H, Guo Y, Zhang J
Basic research in cardiology   93(5) 325-338   Oct 1998   [Refereed]
Nitric oxide synthase is the mediator of late preconditioning against myocardial infarction in conscious rabbits.
Takano H, Manchikalapudi S, Tang XL, Qiu Y, Rizvi A, Jadoon AK, Zhang Q, Bolli R
Circulation   98(5) 441-449   Aug 1998   [Refereed]
Nitric oxide donors induce late preconditioning against myocardial stunning and infarction in conscious rabbits via an antioxidant-sensitive mechanism.
Takano H, Tang XL, Qiu Y, Guo Y, French BA, Bolli R.
Circ Res   83(1) 73-84   Jul 1998   [Refereed]
Qiu Y, Ping P, Tang XL, Manchikalapudi S, Rizvi A, Zhang J, Takano H, Wu WJ, Teschner S, Bolli R.
J Clin Invest   101(10) 2182-2198   May 1998   [Refereed]
Nitric oxide triggers late preconditioning against myocardial infarction in conscious rabbits.
Qiu Y, Rizvi A, Tang XL, Manchikalapudi S, Takano H, Jadoon AK, Wu WJ, Bolli R
The American journal of physiology   273(6 Pt 2) H2931-6   Dec 1997   [Refereed]
The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning.
Bolli R, Manchikalapudi S, Tang XL, Takano H, Qiu Y, Guo Y, Zhang Q, Jadoon AK.
Circ Res   81(6) 1094-1107   Dec 1997   [Refereed]
Extensive calcification in infarcted myocardium: diagnostic value of ultrafast computed tomography. Cardiology.
Takano H, Endo T, Saito T, Hayakawa H.
Cardiology   81 258-261   1992   [Refereed]

Misc

 
Radionuclide determination of therapeutic angiogenesis. Study from critical limb ischemia patients
Takagi Gen, Miyamoto Masaaki, Yasutake Masahiro, Fukushima Yoshimitsu, Kumita Shinichiro, Mizuno Hiroshi, Tara Shuhei, Takano Hitoshi, Kato Koji, Takagi Ikuyo, Mizuno Kyoichi
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   51(10) A168-A169   Mar 2008   [Refereed]
Evidence for the causative role of oxidative stress in the development of contrast-induced nephropathy in patients with chronic kidney disease
Yamamoto Eisei, Takano Hitoshi, Kawashima Shuji, Kawanaka Hidekazu, Takahashi Yasuhiro, Takagi Gen, Fujita Nobuhiko, Aoki Satoshi, Asai Kuniya, Yasutake Masahiro, Takayama Morimasa, Mizuno Kyoichi
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   51(10) A368   Mar 2008   [Refereed]
Renal artery angioplasty improves diastolic cardiac function in patients with heart failure possessing renal artery stenosis
Yamamoto Eisei, Takano Hitoshi, Tajima Hiroyuki, Tanabe Jun, Kawanaka Hdekazu, Tara Shuhei, Takahashi Yasuhiro, Fujita Nobuhiko, Takagi Gen, Aoki Satoshi, Asai Kuniya, Yasutake Masahiro, Takayama Morimasa, Mizuno Kyochi
CIRCULATION   116(16) 379   Oct 2007   [Refereed]
Tara Shuhei, Takagi Gen, Kato Koji, Takano Hitoshi, Takagi Ikuyo, Yasutake Masahiro, Miyamoto Masaaki, Takano Teruo
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY   42 S101   Jun 2007   [Refereed]
Yamamoto Eisei, Takano Hitoshi, Yasutake Masahiro, Aoki Satoshi, Asai Kuniya, Kusama Yoshiki, Takayama Morimasa
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY   42 S172   Jun 2007   [Refereed]
Reduced coronary flow reserve is a predictor of cardiac events in patients with non-ischemic cardiomyopathy as well as in those with cardiac amyloidosis
Takano Hitoshi, Takayama Morimasa, Yamamoto Elsei, Kawashima Shuji, Fujita Nobuhiko, Takagi Gen, Aoki Satoshi, Asai Kuniya, Yasutake Masahiro, Takano Teruo
CIRCULATION   114(18) 766-767   Oct 2006   [Refereed]
[
Nihon rinsho. Japanese journal of clinical medicine   61 Suppl 5 758-766   May 2003   [Invited]
Differential role of KATP channels in late preconditioning against myocardial stunning and infarction in conscious rabbits.
Hitoshi Takano
   Mar 2002

Books etc

 
Delayed preconditioning and adaptive cardioprotection
Bolli R, Dawn B, Tang X, Qiu Y, Ping P, Zhang J, Takano H. (Part:Contributor, Delayed preconditioning against myocardial stunning.)
Kluwer academic publishers,   1998   

Research Grants & Projects

 
Mechanism of Ischemic Preconditioning
Project Year: 2008 - 2010